Riemerella anatipestifer (RA) and application thereof

Abstract

The invention relates to riemerella anatipestifer (RA). The collection number of the RA is CGMCC No.6832. The RA is used for preparing an RA inactivated vaccine. The prepared vaccine can prevent occurrence of infectious serositis of duck characterized by neurological symptom, fibrinous pericarditis, perihepatitis and air sacculitis. The number of RA 6832 in the inactivated vaccine is not less than 1*10<8>CFU / mL. The RA obtained by screening has high pathogenicity. The vaccine prepared from the RA can prevent occurrence of infectious serositis of duck characterized by neurological symptom, fibrinous pericarditis, perihepatitis and air sacculitis, and has good market promotion prospects.

Description

technical field [0001] The invention belongs to the technical field of veterinary biological products, and in particular relates to a Riemerella anatipestifer and its application, that is, a strain of bacteria that can cause duck neurological symptoms, fibrinous pericarditis, perihepatitis and air sac inflammation and its application . Background technique [0002] Duck infectious serositis, also known as Riemerella anatipestifer disease, pasteurella anatipestifer disease, new duck disease, etc., is caused by Riemerella anatipestifer (RA) in ducks, geese, An acute or chronic contagious disease of turkeys and other poultry and wild birds, mainly affecting ducklings aged 2 to 7 weeks, characterized by neurological symptoms and fibrinous pericarditis, perihepatitis and air sacculitis. The disease was first discovered in New York, U.S.A. in 1932. Kuang Ronglu et al. reported the existence of the disease in Guangzhou for the first time in 1975; Guo Yupu et al. (1982) first isola...

AI Technical Summary

Problems solved by technology

[0003] At present, the harm of Riemerella anatipestifer to the breeding industry not only directly causes animal disease and death, but also causes indirect economic losses caused by reduced feed conversion rate and stunted growth of ducks infected with Riemerella anatipestifer. Seriously, although Riemerella anatipestifer is sensitive to some antibacterial drugs, it is difficult to remove, especially after the bacteria invade the airbag, the drug is difficult to reach. The drug resistance rate is high and extensive, and at the same time, it causes certain problems such as drug residues

At present, the important way to prevent the disease is to inoculate the Riemerella anatipestifer vaccine, but there are very few commercial vaccines against the disease in China

Images