Medicament tablet for tonifying kidney and producing sperm and preparation method thereof

A tablet and traditional Chinese medicine technology, which is applied in the field of rapidly disintegrating traditional Chinese medicine composition tablets, can solve the problems of lack of clinical research trials, etc., and achieve the effects of improving semen quality, increasing body weight and hemoglobin content, and increasing plasma testosterone content

Inactive Publication Date: 2013-05-22
GUIZHOU LIANSHENG PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, empiric treatment is mostly used, and there is still a lack of complete clinical research trials

Method used

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  • Medicament tablet for tonifying kidney and producing sperm and preparation method thereof
  • Medicament tablet for tonifying kidney and producing sperm and preparation method thereof
  • Medicament tablet for tonifying kidney and producing sperm and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment l

[0025] Take pilose antler, ginseng, cordyceps sinensis, dodder seed, sealwort, psoralen, eucommia, medlar, sand garden seed, epimedium, mulberry, curculigo, golden cherry, raspberry, sage vine, verbena 46.4g each, Polygonum multiflorum , drynaria and ginkgo leaves are 92.8g each.

[0026] A. Crush antler, ginseng, cordyceps, dodder, sealwort, psoralen, and Eucommia to 80-180 mesh to obtain 324.8 g of fine powder.

[0027] B. Extract the remaining twelve medicines with water, add 10 times the weight of water and decoct three times, the soaking time is 30 minutes, the first decoction time is 1.5 hours, the second decoction time is 1 hour, and the third decoction time is 1 hour. The decoction time is 0.5 hours; after decoction and filtration, the filtrates are combined and concentrated into 426.1 g of liquid extract (solid content 17.86%) with a relative density of 1.25-1.30 at 60°C.

[0028]C. Add the fine powder in step A to the filler (sucrose + starch), dissolution-promoting...

Embodiment 2

[0042] Take pilose antler, ginseng, cordyceps sinensis, dodder seed, sealwort, psoralen, eucommia, medlar, sand garden seed, epimedium, mulberry, curculigo, golden cherry, raspberry, sage vine, verbena 37.12g each, fleece-flower root , drynaria and ginkgo leaves are 97.44g each.

[0043] The preparation method is the same as in Example 1, and the total weight of various auxiliary materials (excluding coating) accounts for 15% of the total weight of the drug.

[0044] Comparative method is the same as comparative example.

Embodiment 3

[0046] Take pilose antler, ginseng, cordyceps, dodder, sealwort, psoralen, eucommia, wolfberry, sand garden seed, epimedium, mulberry, curculigo, golden cherry, raspberry, sage vine, verbena 48.72g each, Polygonum multiflorum , drynaria and ginkgo leaves are 74.24g each.

[0047] The preparation method is the same as in Example 1, and the total weight of various auxiliary materials (excluding coating) accounts for 15% of the total weight of the drug.

[0048] Comparative method is the same as comparative example.

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PUM

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Abstract

The invention discloses a medicament tablet for tonifying kidney and producing sperm and a preparation method thereof. The medicament tablet is used for treating symptoms such as aspermia, oligospermia and sperm weakness resulted from insufficiency of the kidney yang. The medicament tablet takes antler, ginseng, cordyceps, psoralen, polygonum multiflorum, dodder, medlar, polygonatum kingianum, eucommia and the like as raw materials; a low temperature grinding method is combined with a water extracting technology, optimum dosages of functional excipients are optimized by using an orthogonal test method, and then the rapidly disintegrated tablets are prepared. The disintegration time is obviously shortened and the bioavailability is obviously improved.

Description

[technical field] [0001] The invention relates to a traditional Chinese medicine composition tablet for treating azoospermia, oligospermia and asthenospermia and a preparation method thereof. In particular, it relates to a rapidly disintegrating traditional Chinese medicine composition tablet for treating azoospermia, oligozoospermia and asthenospermia. [Background technique] [0002] With the acceleration of the pace of social life and the increasing pressure of life and work, infertility accounts for an increasing proportion of couples of childbearing age all over the world, with about 10% to 15% of infertile people. Report data show that the incidence rate fluctuates between 5% and 35%, of which male factors account for 50%. Since the 20th century, due to factors such as environmental pollution, the spread of sexually transmitted diseases, alcohol abuse, excessive smoking, drug abuse, hormone abuse, lifestyle changes, and excessive life pressure, male fertility has shown...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8969A61P15/08A61K35/32
Inventor 王超志
Owner GUIZHOU LIANSHENG PHARMA
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