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Traditional Chinese medicine extract for treating myasthenia gravis and preparation method thereof

A technology for myasthenia gravis and traditional Chinese medicine, which is applied in pharmaceutical formulations, medical preparations containing active ingredients, drug combinations, etc., can solve problems such as poor long-term effects and obvious side effects, and achieve consolidation of therapeutic effects, accurate curative effects, and improved life. quality effect

Active Publication Date: 2015-03-04
贵州中医药大学第二附属医院
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, Western medicine mainly adopts thymectomy, glucocorticoids, cholinesterase inhibitors and other treatments for its treatment. The short-term effect is acceptable, but the long-term effect is not good. However, Western medicine mostly uses oral hormone drugs for the treatment of myasthenia gravis. Stigmine, prednisone, etc., can only maintain or relieve the temporary status quo, and the side effects are obvious

Method used

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  • Traditional Chinese medicine extract for treating myasthenia gravis and preparation method thereof
  • Traditional Chinese medicine extract for treating myasthenia gravis and preparation method thereof
  • Traditional Chinese medicine extract for treating myasthenia gravis and preparation method thereof

Examples

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Effect test

Embodiment 1

[0144] Preparation method: The above 10 -flavored medicinal materials, add 7.5 times more water for the first time, soak for 0.5 hours, cook for 1 hour, and add 6 times of water each second and third.Liquid, filtering, filtering fluid concentrated to 1000 g, thick extract, 0.5 g hydroxybenzene -phenyl phenyl ester with 95%ethanol 5ml to dissolve and add to the cooling absorbing of the cooling.extract.

[0145] Usage and dosage: 3 times a day, 10g each time.

[0146] Example 2: Ingredients: Astragalus 800g, 300g of white attached tablets, 400g of Epimedium, 250g of Suoyang, 300g of Codonopsis, 300g of White Poria Poria, 150g of Brammer Stir -fried Atractylodes, 300g of Raw Land, 250g of Danshen, 120g of Chenpi.

Embodiment 2

[0147] Preparation method: The above 10 -flavored medicinal materials, add 7.5 times more water for the first time, soak for 0.5 hours, cook for 1 hour, and add 6 times of water each second and third.The solution, filtering, and the filtration liquid concentrated. The 0.5 g hydroxybenne ester is dissolved with 95%ethanol 5ml and adds it to the cooling thick extract.

[0148] Usage and dosage: 3 times a day, 10g each time.

[0149] Example 3: Raw materials: Astragalus 500g, white attached tablets 150g, Epimedium 200g, 100g of Suoyang, 150g of Codonopsis, 150g of white soil Poria, 70g of Bran Fried Atractylodes, 150g of raw land, 100g of wine Danshen, and 30g of Chenpi.

Embodiment 3

[0150] Preparation method: The above 10 -flavored medicinal materials, add 7.5 times more water for the first time, soak for 0.5 hours, cook for 1 hour, and add 6 times of water each second and third.Liquid, filtering, filter liquid concentrated extra ointment, adding 0.5 g hydroxyben phenylth ester (dissolved with 95%ethanol 5ml ethanol) after cooling, mix and fill it, which can treat traditional Chinese medicine extract that treats severe muscle weaknessEssence

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Abstract

The invention discloses a traditional Chinese medicine extract for treating myasthenia gravis and a preparation method thereof. The traditional Chinese medicine extract is prepared from astragalus mongholicus, prepared lateral radix of aconite, herba epimedii, cynomorium songaricum, codonopsis pilosula, rhizoma heterosmilacis japonicae, atractylodes lancea preparata, dried rhizome of rehmannia, salvia miltiorrhiza wine and pericarpium citri reticulatae. The traditional Chinese medicine extract disclosed by the invention is good in curative effect, safe and reliable, convenient to take, fast in medicine release, and accurate in curative effect, and can be used for effectively improving the symptom of a sufferer with myasthenia gravis. The traditional Chinese medicine extract expresses the traditional Chinese medicine characteristics, pays attention to complementing the spleen and stomach, pays attention to treating both symptoms and root causes, and is a safe and reliable traditional Chinese medicine extract for treating myasthenia gravis.

Description

Technical field [0001] The present invention involves the field of traditional Chinese medicine technology, especially Chinese medicine extracts and preparation methods that treat intensive muscle weakness. Background technique [0002] Severe muscle weakness (MG) is a kind of self -immune disease of neuromuscular connecting dysfunction.Its exact pathogenic mechanism is still unclear, but there are still many research on the disease. Among them, the most research is the relationship between the weakness of the intensive muscle weakness and the thymus, and the acetylcholine receptor antibodyStudies have found that the number of acetylcholine receptors (ACHR) on the post -syndrome of the neuro muscles of severe muscle weakness is reduced, anti -Achr antibodies are presented in the receptor site, and IgG and C3 complexes are deposited on the synapses.It also proves that the decrease in the number of effective Achr caused by the increase in anti -Achr antibodies in serum and the depo...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/90A61K36/896A61P21/04
Inventor 况时祥
Owner 贵州中医药大学第二附属医院
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