Evidence-based Screening Method for Prognostic Molecular Markers in Gastric Cancer
A molecular marker and screening method technology, applied in the fields of electrical digital data processing, special data processing applications, instruments, etc., can solve the problems of the research and application process of biomarkers affecting the prognosis of gastric cancer, knowledge accumulation and huge time consumption, etc. The effect of improving application value, reducing human and financial resources, and lowering professional thresholds
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[0034] Embodiment 1. An evidence-based screening method for gastric cancer prognostic molecular markers, the following steps are performed in sequence:
[0035] 1. Formulate inclusion criteria for research evidence: (1) The research population is gastric cancer patients; (2) Evaluate the relationship between biomarkers and clinical effect indicators, and the clinical effect indicators must be overall survival (OS), progression-free survival ( One or more of PFS), chemotherapeutic drug sensitivity, recurrence, toxic side effects, clinicopathological features, etc.; (3) biomarkers include gene mutation, gene polymorphism, mRNA expression level, protein expression level, microRNA and One or several types of microsatellites; (4) provide clear biomarker detection methods; (5) the research design must be randomized controlled trials, cross-sectional studies, cohort studies or systematic reviews (meeting at least one of the above), divided For prospective research and retrospective r...
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