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Veterinary traditional Chinese medicine composition for treating intestinal bacterial infection as well as preparation method and application thereof

A technology of intestinal bacteria and composition, applied in the field of veterinary traditional Chinese medicine composition for treating intestinal bacterial infection

Active Publication Date: 2013-10-09
CHENGDU QIANKUN VETERINARY PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] In summary, there is no report on the simultaneous use of purslane and poplar flower for the treatment of intestinal bacterial infection in piglets

Method used

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  • Veterinary traditional Chinese medicine composition for treating intestinal bacterial infection as well as preparation method and application thereof
  • Veterinary traditional Chinese medicine composition for treating intestinal bacterial infection as well as preparation method and application thereof
  • Veterinary traditional Chinese medicine composition for treating intestinal bacterial infection as well as preparation method and application thereof

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Experimental program
Comparison scheme
Effect test

Embodiment 1

[0024] The preparation of embodiment 1 oral liquid of the present invention and granule

[0025] 1 material

[0026] poplar flower purslane

[0027] 2 methods

[0028] 2.1 Extraction method

[0029] The extraction process of the two medicinal materials was optimized by orthogonal design: add 20 times the amount of water to Yangshuhua, decoct twice for 2 hours each time, filter, and concentrate to 1g / Ml equivalent to the original drug; add 20 times the amount of water to purslane , decocted once, 2h each time, filtered, and concentrated to 1g / Ml equivalent to the original drug.

[0030] 2.2 Preparation method of oral liquid

[0031] Mix the two liquids at a ratio of 1:1, adjust the pH value to 6.2, add the stabilizer dimethylformamide at a ratio of 10% of the total amount of the liquid medicine, and then add 0.1% of the antioxidant sodium metabisulfite, and the metal ion complexing agent EDTA -2Na0.05%, stir to dissolve. Put the prepared medicinal liquid in the refrigerat...

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Abstract

The invention provides a veterinary traditional Chinese medicine composition for treating intestinal bacterial infection. The composition is a preparation prepared from the following raw materials in parts by weight: 1 to 9 parts of poplar flower and 1 to 9 parts of purslane. The invention further provides a preparation method and an application of the veterinary traditional Chinese medicine composition. The pharmacodynamic test proves that poplar flower and purslane which are used together in a specific proportion have a synergistic interaction effect so that the composition has the functions of clearing heat, removing toxicity, cooling blood, dissipating dampness and stopping dysentery.

Description

technical field [0001] The invention relates to a veterinary traditional Chinese medicine composition for treating intestinal bacterial infection. Background technique [0002] Intestinal bacterial infection is a type of disease characterized by severe diarrhea and dehydration. The main pathogens are Escherichia coli and Salmonella. At present, drugs are mainly used to prevent and treat intestinal bacterial infection, and there are also vaccines on the market, but due to the large number of serotypes and the inconsistency of serotypes in different places, good control effects have not been achieved. Among the selected drugs, chemical drugs such as quinolones, aminoglycosides, nitrofurans, quinoxalines, and sulfonamides are still the main ones. Due to long-term non-standard drug use in veterinary clinics, a large number of clinical drug-resistant bacteria have been caused. These commonly used chemical drugs are less effective, and some even have 100% drug resistance, which b...

Claims

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Application Information

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IPC IPC(8): A61K36/76A61P1/00A61P31/04A61P1/12A61K133/00
Inventor 杨海涵李超徐莎李犹平吴学渊丁小刚房春林
Owner CHENGDU QIANKUN VETERINARY PHARMA
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