Device and method for quantitative detection of spectral content distribution of oxygenated hemoglobin and deoxygenated hemoglobin

A technology of deoxygenated hemoglobin and hemoglobin, which is applied in the field of quantitative detection devices for the spectral content distribution of oxygenated hemoglobin and deoxygenated hemoglobin, which can solve the problems of increased pain for the tester, long detection cycle, and increased pain for the test object

Active Publication Date: 2016-03-30
SHANDONG UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

The existing quantitative analysis of these two physiological indicators can only be done through blood tests. The disadvantages are: long detection cycle, increased pain for the test object, etc., and cannot quantitatively describe the distribution of oxygenated hemoglobin and deoxygenated hemoglobin
[0009] However, at present, the quantitative analysis of the above two indicators is mainly through blood tests. The technical disadvantages are: there are disadvantages such as long detection period and increased pain for the testers, and it is impossible to analyze the content distribution of oxygenated hemoglobin and deoxygenated hemoglobin in human tissues. make a quantitative description

Method used

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  • Device and method for quantitative detection of spectral content distribution of oxygenated hemoglobin and deoxygenated hemoglobin
  • Device and method for quantitative detection of spectral content distribution of oxygenated hemoglobin and deoxygenated hemoglobin
  • Device and method for quantitative detection of spectral content distribution of oxygenated hemoglobin and deoxygenated hemoglobin

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Embodiment 1

[0049] Such as figure 1 shown.

[0050] A quantitative detection device for spectral content distribution of oxygenated hemoglobin and deoxygenated hemoglobin, including a light source module, an imaging module, an adjustment bracket, an image data transmission link, a control command transmission link and a computer;

[0051] The light source module includes a connected hyperspectral light source and a controller; the controller is connected to the computer through a control command transmission link; the luminescence band of the hyperspectral light source is 240nm-1550nm; the controller is used for Receive the control command of the computer through the control command transmission link, and then control the hyperspectral light source to start, shut down and select the lighting band of the hyperspectral light source;

[0052] The imaging module includes a lens, a spectrometer, and a hyperspectral imaging component connected in sequence; the hyperspectral imaging component i...

Embodiment 2

[0065] Such as Figure 2-4 shown.

[0066] A method for quantitatively detecting the spectral content distribution of oxygenated hemoglobin and deoxygenated hemoglobin by using the detection device as described in Example 1, comprising the following steps:

[0067] (1) After starting the quantitative detection device for the content distribution of oxygenated hemoglobin and deoxyhemoglobin, the system is initialized, the computer starts the light source module through the control command transmission link, the hyperspectral light source is irradiated on the area to be detected, and the position of the imaging module is adjusted by the adjustment bracket , and achieve lens focusing, hyperspectral image acquisition through the spectrometer hyperspectral imaging module, the hyperspectral image is transmitted to the computer through the image data transmission link, and the hyperspectral image is displayed through the display module;

[0068] (2) The data processing module perfor...

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Abstract

The invention relates to a device for quantitatively detecting the spectral content distribution of oxygenated hemoglobin and deoxygenated hemoglobin. The device comprises a light source module, an imaging module, an adjusting bracket, an image data transmission link, a control command transmission link and a computer. As a technical means of high spectral imaging is adopted, the full cover detection is realized in a detected region, and a characteristic spectrum of the oxygenated hemoglobin and the deoxygenated hemoglobin is extracted through using a spectral decomposition technology, the calculation is carried out by utilizing a regional oxygen saturation computational formula, and the device and the method have the characteristics of acquiring comprehensive information and being high in precision without any reagent.

Description

technical field [0001] The invention relates to a quantitative detection device and method for spectral content distribution of oxygenated hemoglobin and deoxygenated hemoglobin, belonging to the technical field of biomedical engineering. technical background [0002] Hemoglobin is an important part of blood cells that is responsible for transporting oxygen from the lungs to other tissues in the body. Oxygenated hemoglobin content and deoxygenated hemoglobin content are two important physiological indicators. Existing quantitative analysis of these two physiological indicators can only be done through blood tests. The disadvantages are: long detection cycle, increased pain to the test subjects, etc., and cannot quantitatively describe the distribution of oxygenated hemoglobin and deoxygenated hemoglobin. [0003] Oxygenated hemoglobin and deoxygenated hemoglobin have different absorption characteristics in the visible and near-infrared spectral ranges, deoxygenated hemoglob...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): G01N21/31
Inventor 刘治
Owner SHANDONG UNIV
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