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Pharmaceutical composition for treating malignant tumor, preparation method and application

A technology for malignant tumors and compositions, which is applied in drug combinations, antineoplastic drugs, and pharmaceutical formulations, and can solve the problems of complex drug preparation process, expensive finished drug products, and low efficacy

Inactive Publication Date: 2013-12-25
SHANGHAI UNIV OF T C M
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, there are many traditional Chinese medicine preparations for the treatment of malignant tumors on the market. Some medicines have complicated preparation process and expensive finished medicines, which affect the popularization and use of medicines; while some medicines have unsatisfactory clinical efficacy, long treatment cycle and low effective rate. , high recurrence rate and other problems, and most of the traditional Chinese medicine preparations used in clinical treatment of tumors have complicated prescriptions, and some medicines also contain drugs with large toxic and side effects, which bring more adverse reactions to patients when used

Method used

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  • Pharmaceutical composition for treating malignant tumor, preparation method and application
  • Pharmaceutical composition for treating malignant tumor, preparation method and application
  • Pharmaceutical composition for treating malignant tumor, preparation method and application

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0028] Example 1 A pharmaceutical composition was prepared according to the raw material in the following parts by weight ratio,

[0029] 3 parts of Scrophulariae, 2 parts of Curcuma, 4 parts of Fritillaria, 2 parts of Fried Atractylodes, 10 parts of raw oysters, 10 parts of Vinegar Turtle Carapace,

[0030] (1) Take zedoary and stir-fry Atractylodes atractylodes in parts by weight, and extract the volatile oil for later use;

[0031] (2) Take curcuma and fried Atractylodes dregs in the above step (1), fry together with Scrophularia scrophulariae, Fritillaria, raw oysters, and vinegar turtle shells. The raw oysters and vinegar turtle shells are first fried for 30 minutes, and then add 8 -10 times the amount of water to decoct twice, the first decoction for 40-60 minutes, the second decoction for 25-30 minutes, combine the two liquid medicines, filter, discard the residue, and concentrate the filtrate for later use;

[0032] (3) Combine and mix the medicinal liquid concentrate...

Embodiment 2

[0035] Example 2 Prepare a pharmaceutical composition according to the raw material drug in the following parts by weight ratio,

[0036] 15 parts of Radix Scrophulariae, 20 parts of Curcuma, 20 parts of Fritillaria Fritillaria, 15 parts of fried Atractylodes macrocephala, 30 parts of raw oysters, 30 parts of vinegar turtle, the pharmaceutical composition is prepared by the following method:

[0037] (1) Take zedoary and stir-fry Atractylodes atractylodes in parts by weight, and extract the volatile oil for later use;

[0038] (2) Take curcuma and fried Atractylodes dregs in the above step (1), fry together with Scrophularia scrophulariae, Fritillaria, raw oysters, and vinegar turtle shells. The raw oysters and vinegar turtle shells are first fried for 30 minutes, and then add 8 -10 times the amount of water to decoct twice, the first decoction for 40-60 minutes, the second decoction for 25-30 minutes, combine the two liquid medicines, filter, discard the residue, and concentr...

Embodiment 3

[0041] Example 3 A pharmaceutical composition was prepared according to the following raw materials in proportions by weight,

[0042] 2 parts of Scrophulariae, 2 parts of Curcuma, 2 parts of Fritillaria, 1 part of Fried Atractylodes, 3 parts of Raw Oyster, 2 parts of Vinegar Turtle Carapace,

[0043] Prepare the described pharmaceutical composition by the following method, it comprises steps:

[0044] (1) Take zedoary and stir-fry Atractylodes atractylodes in parts by weight, and extract the volatile oil for later use;

[0045] (2) Take curcuma and fried Atractylodes dregs in the above step (1), fry together with Scrophularia scrophulariae, Fritillaria, raw oysters, and vinegar turtle shells. The raw oysters and vinegar turtle shells are first fried for 30 minutes, and then add 8 -10 times the amount of water to decoct twice, the first decoction for 40-60 minutes, the second decoction for 25-30 minutes, combine the two liquid medicines, filter, discard the residue, and concent...

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Abstract

The invention relates to the field of traditional Chinese medicines, and relates to a pharmaceutical composition for treating malignant tumor, a preparation method and an application. The pharmaceutical composition is prepared by radix scrophulariae, rhizoma curcumae, fritillary bulb, roasted rhizoma atractylodis macrocephalae, raw oyster shell and vinegar turtle. The pharmaceutical composition has the functions of softening hard lumps and dispelling nodes, strengthening body resistance and resisting cancer. In-vivo and in-vitro experimental results show that the pharmaceutical composition has significant effect for inhibiting the cancer, has good stability and small toxic and side effects, and has good treating effects for a plurality of malignant tumors such as stomach cancer, lung cancer, esophageal cancer, liver cancer, cervical cancer and breast cancer. The preparation method of the pharmaceutical composition is simple; and the pharmaceutical composition is high in safety and efficiency, low in cost and wide in clinical applications.

Description

technical field [0001] The invention belongs to the field of traditional Chinese medicine, and relates to a pharmaceutical composition for treating malignant tumors, and also relates to a preparation method of the composition and its application in medicine. Background technique [0002] Malignant tumor is a major disease that seriously endangers human life and health, and its mortality rate ranks first in the death toll of human diseases. According to statistics, the incidence and death of malignant tumors in the world have increased by about 22.0% in the past 10 years. It is estimated that by 2020, there will be nearly 20 million new cases per year, and the number of deaths will reach 12 million per year; and my country, as a developing country As a country with a large population, the situation is even more severe. According to statistics, in the past 20 years, the cancer mortality rate in my country has increased by 29%, and one out of every four or five deaths is due to ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/9066A61P35/00A61K35/56A61K35/586A61K35/618
Inventor 朱国福郭晨旭李文龙潘颖宜高玉琼
Owner SHANGHAI UNIV OF T C M
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