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Hepatoprotective composition as well as preparation method and application thereof

A technology of composition and preparation, applied in the field of composition for liver protection, to achieve obvious therapeutic effect and preventive effect

Active Publication Date: 2014-01-01
WEST CHINA HOSPITAL SICHUAN UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0008] There is no report on the combination of proanthocyanidins, α-lipoic acid, and N-acetyl-L-cysteine ​​in milk thistle, green tea, and acai berry for liver protection

Method used

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  • Hepatoprotective composition as well as preparation method and application thereof
  • Hepatoprotective composition as well as preparation method and application thereof
  • Hepatoprotective composition as well as preparation method and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0040] The preparation of embodiment 1 microemulsion of the present invention

[0041] Composition ratio: (content per 100ml microemulsion)

[0042]

[0043]Add 100mL of PEG400 to 24g of the above ratio mixture, mix, add 200mL of soybean oil, stir and mix at a constant temperature of 70°C, then add 60mL of polysorbate 80, 50mL of glycerin, and 1500ml of water, and then stir at a constant temperature of 70°C Obtain the oil phase, then stir and drop the oil phase into an appropriate amount of water at a uniform speed, obtain a microemulsion preparation by emulsifying and dispersing, and add water to adjust the final volume to 2L. The particle size characterization of microemulsion preparations is as follows: figure 1 shown.

Embodiment 2

[0044] The preparation of embodiment 2 microemulsions of the present invention

[0045] Composition ratio: (content per 100ml microemulsion)

[0046]

[0047] The preparation method is the same as in Example 1.

Embodiment 3

[0048] The preparation of embodiment 3 microemulsions of the present invention

[0049] Composition ratio: (content per 100ml microemulsion)

[0050]

[0051]

[0052] The preparation method is the same as in Example 1.

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Abstract

The invention discloses hepatoprotective composition. The hepatoprotective composition is prepared from the following raw materials: a milk thistle extract, a green tea extract, an Acai berry extract, alpha-lipoic acid and N-acetyl-L-cysteine. The invention further discloses a preparation method and an application of the hepatoprotective composition. The hepatoprotective composition combines the milk thistle extract, the green tea extract, the Acai berry extract, the alpha-lipoic acid and the N-acetyl-L-cysteine for use, so that the hepatoprotective composition has a significant hepatoprotective function and can be used for treating and / or preserving acute liver injuries and chronic liver injuries.

Description

technical field [0001] The present invention relates to a composition for protecting the liver. Background technique [0002] The liver is an important detoxification organ of the body. Toxic substances absorbed by the gastrointestinal tract must be detoxified in the liver to become non-toxic substances, and then excreted through bile or urine. The "liver" as described in TCM is mainly responsible for storing blood and dredging. Storing blood is to store nutrients for the body, while dredging refers to the dredging and regulating (metabolism) function of the body. Unreasonable diet and living habits in daily life will cause mild or severe damage to the liver, so the protection of the liver is particularly important. [0003] Milk thistle, also known as large thistle and milk thistle, is the fruit of milk thistle, a plant of the Compositae family, and its main active ingredient is silymarin. Silymarin is the general term for compounds such as silybin, dehydrosilibinin, sil...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/889A61K36/82A61P1/16A23L1/305A61K31/385A61K31/198A23L33/105A23L33/15A23L33/17
Inventor 李涛杨倩张乃月冉晓红陈艳芳刘进
Owner WEST CHINA HOSPITAL SICHUAN UNIV
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