Soluble hemostatic gauze and its preparation method

Abstract

The invention relates to a hemostatic medicament and in particular relates to soluble stanching gauze and a preparation method thereof. The soluble stanching gauze comprises methylcellulose generated by reaction of absorbent gauze, sodium hydroxide and methyl chloride in an isopropanol solvent in a weight ratio of 1 to 1 to 1.2. The preparation method comprises the following steps: washing by water, alkalifying, etherifying, washing by hot water, neutralizing and drying to prepare a semi-finished product; checking to ensure that the semi-finished product is qualified; and weighing, cutting and packaging. The soluble stanching gauze provided by the invention is good in moisture absorptivity, quickly absorbs blood for expansion and dissolves the blood after meeting the blood and can form a covering together with blood clots, and dissolving methylcellulose is high in water-retention rate, so that the wettability of the surface of a wound is kept, the tissue healing speed can be increased, and the effects of quickly and effectively stopping bleeding and protecting the surface of a wound are achieved.

Description

technical field [0001] The invention relates to the field of medicine, in particular to a soluble hemostatic gauze and a preparation method thereof. Background technique [0002] At present, the hemostatic agents used in surgical operations and wound bleeding are usually injection and external application. The earlier hemostatic agents, Yunnan Baiyao and other external application hemostatic agents have a slow hemostatic speed and ineffective effect; in recent years, the hemostatic agents that use shrimp shells as raw materials Medicine can quickly stop bleeding, but the process is complicated and the cost is high. [0003] Hemostatic gauze is widely used in the medical and health field, but the gauze will stick to the wound during use, which is easy to cause secondary trauma, and the waste after use will pollute the environment. In response to the above problems, since the early 1990s, soluble hemostatic gauzes have come out one after another. For example, the invention p...

AI Technical Summary

Problems solved by technology

For example, the invention patents with Chinese patent numbers 91110511 and 9810676 provide soluble gauze that can fill and cover various wounds, promote platelet coagulation, and achieve the purpose of hemostasis. Solve the problem of postoperative adhesion

[0004] At the same time, the hemostatic gauze of these patents must use monochloroacetic acid as a raw material in the preparation process. Monochloroacetic acid is highly toxic, which not only requires high production and preparation equipment, but also brings harm to the health of operators.