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Oil-in-water skin external preparation

A skin external preparation, oil-in-water type technology, applied in the field of oil-in-water type skin external preparation, can solve the problem of detrimental stability over time, separation of pulp, no means of stabilizing oil-in-water emulsion composition, etc. problem, to achieve the effects of excellent thick feeling, suppression of the occurrence of pulp separation, and excellent stability over time

Active Publication Date: 2015-08-05
SHISEIDO CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, if high-molecular-weight polyethylene glycol is blended in an oil-in-water emulsified composition, the feeling of richness will be improved, but the stability over time will be impaired, and segregation will occur.
So far, no means have been proposed for stabilizing oil-in-water emulsion compositions containing high molecular weight polyethylene glycol

Method used

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  • Oil-in-water skin external preparation
  • Oil-in-water skin external preparation
  • Oil-in-water skin external preparation

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1～2 and comparative example 1～7

[0071] An oil-in-water external preparation for skin having a composition shown in the following Table 1 was prepared, used as a sample, and evaluated for usability and stability over time according to the above-mentioned evaluation criteria. The results are shown in Table 1 together.

[0072] (preparation method)

[0073] Completely dissolve the oil phase part ((7)-(18)) and the water phase part ((1)-(6) and (19)-(21)) respectively at 70°C, and add the oil phase part to the water phase Stirring and emulsification at 70° C., after that, adjustment of emulsified particle size using a homomixer at 65° C., cooling to room temperature, and obtaining cream.

[0074] [Table 1]

[0075]

[0076] As can be seen from the results shown in Table 1, the oil-in-water type containing all substances in high molecular weight polyethylene glycol, higher alcohol, N-stearyl-N-methyl taurate sodium and nonionic surfactant The skin external preparation (Example 1) showed excellent results in...

Embodiment 3 and comparative example 8～10

[0080] An oil-in-water external preparation for skin having a composition shown in Table 2 below was prepared in the same manner as above, and was used as a sample, and usability and stability over time were evaluated in accordance with the above-mentioned evaluation criteria. The results are shown in Table 2 together.

[0081] [Table 2]

[0082]

[0083] As can be seen from the results shown in Table 2, even if an equivalent amount of sodium palmitoyl methyl taurate (comparative example 8) having a structure similar thereto was blended instead of N-stearyl-N-methyl taurate sodium, Sodium cocoyl methyl taurate (comparative example 9) and sodium laurate methyl taurate (comparative example 10) did not obtain sufficient temporal stability either.

Embodiment 4～5 and comparative example 11

[0085] An oil-in-water external preparation for skin having a composition shown in Table 3 below was prepared in the same manner as above, and was used as a sample, and usability and stability over time were evaluated in accordance with the above-mentioned evaluation criteria. The results are shown in Table 3 together.

[0086] [table 3]

[0087]

[0088] As can be seen from the results shown in Table 3, if the compounding amount of N-stearyl-N-methyl taurate is too much, the sticky, greasy, impair usability.

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Abstract

Provided is an oil-in-water-type external preparation for the skin, which contains a high-molecular-weight polyethylene glycol, and has excellent rich texture, excellent long-term stability in a broad environmental temperature range from a lower temperature to a higher temperature and a good sensation upon application. The oil-in-water-type external preparation for the skin is characterized by comprising (a) a high-molecular-weight polyethylene glycol, (b) a higher alcohol, (c) sodium N-stearoyl-N-methyltaurine in an amount of less than 2.0 mass%, and (d) a nonionic surfactant. The high-molecular-weight polyethylene glycol is preferably polyethylene glycol 20000, and the nonionic surfactant (d) is preferably contained in an amount of 1.0 to 10.0 mass% relative to the total amount of the oil-in-water-type external preparation for the skin.

Description

technical field [0001] The present invention relates to an oil-in-water external preparation for skin, and more specifically, relates to an oil-in-water external preparation for skin that has excellent richness and excellent stability over time in a wide range of ambient temperatures from low to high temperatures. Background technique [0002] The oil-in-water emulsion composition has a moist and refreshing feeling, so it is suitable for skin cosmetics such as skin creams. However, in general, an emulsified composition is obtained by forcibly dispersing an inherently immiscible water phase and an oil phase with an emulsifier, and thus is remarkably unstable due to the blended components, causing phase separation (syringe). [0003] For example, various electrolytes such as organic acid salts and inorganic acid salts are formulated for the purpose of imparting moisturizing, astringent, and keratolytic effects to the skin, or polar oils are formulated for the purpose of impart...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K8/34A61K8/06A61K8/46A61K8/86A61Q19/00
CPCA61K8/466A61K8/86A61Q19/00A61K8/342A61K8/062
Inventor 松浦有宇子大村孝之大平光
Owner SHISEIDO CO LTD
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