Anti-influenza drug and preparation method thereof

A technology for influenza and medicine is applied in the field of medicine for cold and its preparation, which can solve the problems of large dosage, inconvenience to carry, and difficulty of Western medicine to play an ideal role, and achieves the effects of reducing mortality and prolonging survival days.

Active Publication Date: 2014-03-26
XINJIANG INST OF MATERIA MEDICA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] The present invention provides an anti-influenza drug and its preparation method, which overcomes the above-mentioned deficiencies in the prior art, and can effectively solve the problem that western medicine is difficult to exert an ideal effect. And traditional Chinese medicine decoctions have a great impact on clinical efficacy, large dosage and inconvenient to carry

Method used

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  • Anti-influenza drug and preparation method thereof
  • Anti-influenza drug and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0023] Example 1, the anti -epidemic cold drug, the raw material is forming 1 to 3 artemisia, 1 to 3 parts of Banlangen, 1 to 3 copies of the golden lotus.

Embodiment 2

[0024] Example 2, the anti -epidemic cold drug, the raw material is forming 1 or 3 parts or 3 parts, 1 or 3 parts of Banlangen, 1 or 3 copies of the golden lotus.

Embodiment 3

[0025] Example 3: The anti -influenza drug obtained by the preparation method. The first step is to crush the required volume of the panel blue root rough powder, and add 6 times to 10 times to 10 times to 10 times the linked pink powder.Soak for 24h to 48h, the return extract 2 to 4 times, the temperature of each return extract is 80 ° C to 110 ° C, the time of each return extract is 0.5h to 1.5h, and the filtering of water extraction solution and medicine after each return extract is extracted.Slag, and then add 6 times to 10 times the water of the Banlang root thick powder to the next extraction to the filtering medicine residue. After the return extract 2 to 4 times, the water extraction solution obtained each time is merged together to get the water to get the water to get the water to get the water to get the water to get the water to get the waterLifting the mixture, concentrate the hybrid hybrid hybrid fluid to get a density at a temperature of 1.22 to 1.25 at a temperatur...

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Abstract

The invention relates to the technical field of cold drugs and preparation methods thereof and in particular relates to an anti-influenza drug and a preparation method thereof. The anti-influenza drug is prepared from the raw materials in parts by weight: 1-3 parts of Artemisia rupestris, 1-3 parts of isatidis root and 1-3 parts of globeflower. With the adoption of the anti-influenza drug, average IC50 (Half Maximal Inhibitory Concentration) of the anti-influenza drug to an influenza A virus and an influenza B virus are respectively 115.86 micrograms/ml and 132.28 micrograms/ml, and average TI (Therapeutic Index) of the anti-influenza drug to the influenza A virus and the influenza B virus are respectively 8.8 and 7.7; a 0.2g/kg dosage group of the anti-influenza drug is capable of obviously prolonging survival days of a mice which is infected by the influenza A virus, and the death rate is lowered; a 0.1g/kg dosage group and the 0.2g/kg dosage group are capable of obviously inhibiting a lung exponential value, and average inhibition ratios are respectively 19.4 percent and 28.0 percent. The anti-influenza drug has certain actions of preventing the influenza virus in vivo and in vitro and provides the pharmacology basis for treating influenza.

Description

Technical field [0001] The invention involves the technical field of cold drugs and its preparation methods, which is a kind of anti -influenza drug and its preparation method. Background technique [0002] Popular cold (referred to as influenza) is an acute respiratory infectious disease caused by Influenza Virus (IFV), which can cause myocarditis, pneumonia, bronchitis and other complications.It is usually manifested as the symptoms of upper respiratory tract infections such as headache, sore throat, cough and other symptoms of headache, sore throat, cough.It has the characteristics of high incidence, rapid onset, rapid spread, wide popularity, large variability, strong infectious power, and accompanied by certain mortality. [0003] Influenza is an acute respiratory infectious disease that is caused by influenza virus that endangers human health, which often causes seasonal global or local regions."Spanish flu" in 1918 caused more than 20 million people in the world.Subsequent...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/71A61P31/16
Inventor 邢建国何承辉古丽斯坦·阿吾提姜雯
Owner XINJIANG INST OF MATERIA MEDICA
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