A kind of traditional Chinese medicine composition with antitumor activity

A technology of anti-tumor activity and composition, applied in the direction of anti-tumor drugs, drug combinations, medical preparations containing active ingredients, etc. Growth promotion, strong killing effect, wide application effect

Active Publication Date: 2017-06-23
NANJING UNIVERSITY OF TRADITIONAL CHINESE MEDICINE
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  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

Clinically, the current drugs for treating tumors mainly include chemical drugs. However, due to the high toxicity of chemotherapy drugs, they can not selectively kill white blood cells, lymphocytes and other human immune cells while killing tumor cells. As a result, patients often suffer from autoimmune diseases. Complicated infection due to low ability, large adverse reactions in patients, long course of treatment, high cost, and great limitations in clinical use

Method used

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  • A kind of traditional Chinese medicine composition with antitumor activity
  • A kind of traditional Chinese medicine composition with antitumor activity

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Experimental program
Comparison scheme
Effect test

Embodiment 1

[0029] 1. Composition of raw materials of traditional Chinese medicine composition with anti-tumor activity:

[0030] 30 parts of ginseng, 30 parts of Ophiopogon japonicus, 30 parts of Hedyotis diffusa, 30 parts of Banzhilian, 10 parts of Aracea, and 30 parts of Curcuma.

[0031] 2. The preparation method of the traditional Chinese medicine composition preparation with antitumor activity:

[0032] (1) Take 30 parts of ginseng, add 15 times the amount of water of medicinal materials, ultrasonically extract 3 times, each time for 3 hours, to obtain water extract, concentrate, extract with n-butanol to obtain n-butanol extract, put it on a macroporous resin column, Rinse with water, then elute with 20-50% ethanol to obtain ethanol eluent, dry in vacuum to obtain ginseng extract, and set aside;

[0033] (2) Take 30 parts of Ophiopogon japonicus, 30 parts of Hedyotis diffusa, 30 parts of Scutellaria barbata, 10 parts of Araceae, and 30 parts of Curcuma, add 10 times the concentrat...

Embodiment 2

[0036] 1. Composition of raw materials of traditional Chinese medicine composition with anti-tumor activity:

[0037] 45 parts of ginseng, 45 parts of Ophiopogon japonicus, 60 parts of Hedyotis diffusa, 60 parts of Banzhilian, 20 parts of Aracea, 45 parts of Curcuma.

[0038] 2. The preparation method of the traditional Chinese medicine composition preparation with antitumor activity:

[0039] (1) Take 45 parts of ginseng, add 8 times the amount of water of the medicinal material, extract by ultrasonic or decocting 3 times, each time for 2 hours, to obtain a water extract, concentrate, extract with n-butanol to obtain an extract with n-butanol, and apply the macropore Rinse the resin column with water, and then elute with 20-50% ethanol to obtain an ethanol eluent, dry it in vacuum to obtain ginseng extract, and set aside;

[0040] (2) Take 45 parts of Ophiopogon japonicus, 60 parts of Hedyotis diffusa, 60 parts of Scutellaria barbata, 20 parts of Araceae, and 45 parts of Cur...

Embodiment 3

[0043] 1. Composition of raw materials of traditional Chinese medicine composition with anti-tumor activity:

[0044] 40 parts of ginseng, 40 parts of Ophiopogon japonicus, 60 parts of Hedyotis diffusa, 60 parts of Banzhilian, 15 parts of Aracea, and 40 parts of Curcuma.

[0045] 2. The preparation method of the traditional Chinese medicine composition preparation with antitumor activity:

[0046] (1) Take 40 parts of ginseng, add 10 times the amount of water, ultrasonic or decoct to extract twice, each time for 3 hours, to obtain water extract, concentrate, extract with n-butanol to obtain n-butanol extract, and apply macropores Rinse the resin column with water, and then elute with 20-50% ethanol to obtain an ethanol eluent, dry it in vacuum to obtain ginseng extract, and set aside;

[0047] (2) Take 40 parts of Ophiopogon japonicus, 60 parts of Hedyotis diffusa, 60 parts of Banzhilian, 15 parts of Aracea, and 40 parts of Curcuma. Add 70% ethanol with 12 times the concentr...

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Abstract

The invention discloses a traditional Chinese medicine composition with antitumor activity, which is prepared from the following raw materials in parts by weight: 30-60 parts of ginseng, 20-40 parts of Radix Ophiopogon japonicus, 30-50 parts of Hedyotis diffusa, half Zhilian 10~40 parts, Aracea 10~20 parts, Curcuma 10~30 parts. According to the theory of traditional Chinese medicine, the present invention adopts the theory of syndrome differentiation and treatment to screen the prescriptions of traditional Chinese medicines, and the proportion of the Chinese medicine composition is scientific and reasonable. It has a strong killing effect on a variety of malignant tumor cells, and has a wide range of applications; it can significantly reduce the pain of tumor patients, prolong the survival period, and improve the quality of life of patients. Long-term experimental studies have shown that the present invention The provided traditional Chinese medicine composition has high safety, low toxicity and side effects, and can be developed into a new antitumor drug.

Description

technical field [0001] The invention relates to a traditional Chinese medicine composition, in particular to a traditional Chinese medicine composition with antitumor activity, and belongs to the technical field of medicine and pharmacy. Background technique [0002] Tumor has become the number one killer threatening human survival in the 21st century, with an average of more than 6 million people dying of various tumor diseases every year. China is one of the countries with a high incidence of cancer in the world, with more than 2 million new cancer patients every year, accounting for 20% of the global total. There are more than 4 million cancer patients, and there is a rapid growth trend every year. Clinically, the current drugs for treating tumors mainly include chemical drugs. However, due to the high toxicity of chemotherapy drugs, they can not selectively kill white blood cells, lymphocytes and other human immune cells while killing tumor cells. As a result, patients o...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/9066A61P35/00A61P35/02
Inventor 程海波沈卫星孙东东尚文斌周学平吴勉华周仲瑛
Owner NANJING UNIVERSITY OF TRADITIONAL CHINESE MEDICINE
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