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Compound niclosamide chewing tablet used for dogs and cats

A technology of compound niclosamide and niclosamide, applied in the field of compound niclosamide chewable tablets and its preparation, to achieve good taste, improve oral bioavailability, and increase compliance

Inactive Publication Date: 2014-06-25
QINGDAO VLAND BIOTECH INC
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Changshanone is a new broad-spectrum anticoccidial drug, no adverse reactions have been found so far, and there is no cross-resistance with other anticoccidial drugs

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0017] Prescription composition:

[0018] Niclosamide 10mg

[0019] Praziquantel 5mg

[0020] Pyrantel 15mg

[0021] Hemosanone 5mg

[0022] Microcrystalline Cellulose 23mg

[0023] Starch 30mg

[0024] Magnesium Stearate 2mg

[0025] Beef Flavor 10mg

[0026] Total 100mg per tablet

[0027] Preparation method: Pass praziquantel, pyrantel, niclosamide, fushenone, microcrystalline cellulose, and starch through a 100-mesh sieve and mix evenly, use an appropriate amount of alcohol to make a soft material, granulate with a 20-mesh sieve, dry, and use a 20-mesh sieve Sieve whole grains, add beef essence and magnesium stearate, mix well, and press into tablets to obtain.

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PUM

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Abstract

The invention discloses a compound niclosamide chewing tablet used for dogs and cats. The active components of the chewing tablet comprise praziquantel, pyrantel, niclosamide and halofuginone. The chewing tablet overcomes a disadvantage of poor palatability of traditional tablets, allows the dogs and the cats to fully chew the medicine, and guarantees full adsorption of the medicine and exertion of good medicine effects. The tablet provided by the invention comprises following components by weight: 10-20% of the niclosamide, 5-10% of the praziquantel, 15-25% of the pyrantel, 5-10% of the halofuginone, 30-50% of a filling agent, 0.5-3% of an adhesive and 5-15% of a corrigent. The chewing tablet is simple in preparation process, good in product taste, stable in product quality, and suitable for industrial production.

Description

technical field [0001] The invention relates to a compound niclosamide chewable tablet for expelling nematodes, tapeworms and protozoa in dogs and cats and a preparation method thereof. Background technique [0002] At present, there are many medicines for treating nematodes and tapeworms in dogs and cats in the pet market, but due to the serious mixed feeling of parasites in pets, there is currently a lack of antiparasitic medicines on the market that can treat nematodes, tapeworms and protozoa at the same time. Therefore, we have developed a highly efficient, comprehensive and safe antiparasitic drug. Its main ingredients include praziquantel (Praziquantel), pyrantel (Pyrantel), niclosamide (Febental) and halofuginone (Halofuginone). Praziquantel is clinically effective against Schistosomiasis japonicum, Taeniasis, Clonorchiasis, and Paragonimiasis. Pyrantel is mainly used clinically to drive away roundworms, hookworms, and pinworms. Niclosamide is a benzimidazole precu...

Claims

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Application Information

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IPC IPC(8): A61K31/517A61K31/506A61K31/4985A61K31/167A61K9/20A61P33/10A61P33/02A61P33/00
Inventor 张瑞丽邱梅
Owner QINGDAO VLAND BIOTECH INC