Application of traditional Chinese medicine composition in preparation of medicine for treating pneumoconiosis

A composition and technology of traditional Chinese medicine, applied in the application field of traditional Chinese medicine composition in the preparation of medicines for treating pneumoconiosis, can solve the problems of liver and kidney damage, single action and effect, etc., and achieve improvement of chest tightness, breathlessness, ventilation and heart The effect of the function

Active Publication Date: 2014-07-23
HEBEI YILING MEDICINE INST
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] In the 1970s, China actively carried out drug screening research and clinical new drug research for the treatment of pneumoconiosis, and new drugs for the treatment of pneumoconiosis also appeared one after another, such as: P204, Hanfang has A, aluminum citrate, etc. These drugs can effectively resist the fibrosis of pneumoconiosis, but the effect is relatively simple, and there is a certain degree of liver and kidney damage; in the 1980s, bronchoalveolar lavage was carried out to treat pneumoconiosis. Created a precedent for the etiological treatment of coal workers' pneumoconiosis, but it is prone to other respiratory complications, such as pneumonia; around the 1990s, small-volume lung lavage was used to treat pneumoconiosis. Compared with bronchoalveolar lavage, this method has improved Clinical effect: The Pneumoconiosis Rehabilitation Center of the State Coal Mine Safety Supervision and Supervision Bureau has carried out large-volume whole lung lavage in the treatment of coal workers' pneumoconiosis and other respiratory diseases since 1991, and has treated more than 2,480 patients with pneumoconiosis, all of which have achieved satisfactory results

Method used

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  • Application of traditional Chinese medicine composition in preparation of medicine for treating pneumoconiosis
  • Application of traditional Chinese medicine composition in preparation of medicine for treating pneumoconiosis

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0040] Embodiment 1: the preparation of pharmaceutical capsule of the present invention

[0041] prescription:

[0042] Astragalus 450g Aconite 112.5g Ginseng 225g Salvia miltiorrhiza 225g Tinglizi 150g

[0043] Xiangjia skin 180g Alisma 225g safflower 90g Polygonatum 75g Chenpi 75g Guizhi 90g

[0044] Preparation:

[0045] (1) Reflux extract astragalus, Tinglizi, Alisma, ginseng, and Xiangjia bark according to the above prescription plus 8 times the amount of 70% ethanol for 2 times, the first time for 3 hours, and the second time for 2 hours, combine the extracts, filter The filtrate was decompressed to recover ethanol, concentrated to a clear paste with a relative density of 1.25 during thermal measurement at 60°C, and set aside;

[0046] (2) Distill cinnamon sticks and tangerine peel to extract volatile oil according to the prescription, filter the aqueous solution after oil extraction, and set aside, add 8 times the amount of water to the residue and decoct for 1 hou...

Embodiment 2

[0049] Embodiment 2: the preparation of pharmaceutical tablet of the present invention

[0050] prescription:

[0051] Astragalus 150g Aconite 40g Ginseng 225g Salvia 225g Tinglizi 50g

[0052] Xiangjiapi 180g Alisma 75g Polygonatum 75g Guizhi 30g Safflower 90g Chenpi 25g

[0053] Preparation:

[0054] (1) Extract astragalus, Tinglizi, Alisma, ginseng, and Xiangjia bark according to the above prescription and add 7 times the amount of 70% ethanol to reflux twice, the first time for 3 hours, and the second time for 2 hours, combine the extracts, filter The filtrate was decompressed to recover ethanol, concentrated to a clear paste with a relative density of 1.30 during thermal measurement at 60°C, and set aside;

[0055] (2) Distill cinnamon sticks and tangerine peel to extract volatile oil according to the prescription amount, filter the aqueous solution after oil extraction, and set aside, add 6 times the amount of water to the residue and decoct for 1 hour, filter, comb...

Embodiment 3

[0058] Embodiment 3: the preparation of medicament oral liquid of the present invention

[0059] prescription:

[0060] Astragalus 250g Aconite 112.5g Codonopsis 200g Salvia 120g Tinglizi 135g

[0061] Nanwujiapi 150g Alisma 200g Polygonatum 60g Guizhi 75g Safflower 75g Chenpi 60g

[0062] Preparation:

[0063] (1) Reflux extract astragalus, Tinglizi, Alisma, ginseng, and Xiangjia bark according to the above prescription plus 8 times the amount of 70% ethanol for 2 times, the first time for 3 hours, and the second time for 2 hours, combine the extracts, filter The filtrate was decompressed to recover ethanol, concentrated to a clear paste with a relative density of 1.25 during thermal measurement at 60°C, and set aside;

[0064] (2) Distill cinnamon sticks and tangerine peel to extract volatile oil according to the prescription, filter the aqueous solution after oil extraction, and set aside, add 8 times the amount of water to the residue and decoct for 1 hour, filter, co...

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Abstract

The invention discloses an application of a traditional Chinese medicine composition in preparation of a medicine for treating pneumoconiosis, and belongs to the field of new uses of traditional Chinese medicines. The traditional Chinese medicine composition comprises radix astragali, aconite root, ginseng or radix codonopsitis, red sage root, semen lepidii, cortex periplocae or cortex acanthopanacis, rhizoma alismatis, radix polygonati officinalis, cassia twig, safflower and dried orange peel. The traditional Chinese medicine composition has a function of improving the pulmonary ventilation volume.

Description

technical field [0001] The invention relates to a new application of a traditional Chinese medicine composition, in particular to an application of a traditional Chinese medicine composition in preparing medicine for treating pneumoconiosis. Background technique [0002] Pneumoconiosis is a systemic disease mainly caused by diffuse fibrosis (scarring) of lung tissue caused by long-term inhalation of productive dust (dust) during occupational activities and retention in the lungs. According to the different types of dust inhaled, pneumoconiosis can be divided into inorganic pneumoconiosis and organic pneumoconiosis. Main symptoms: Cough, expectoration, chest pain, dyspnea. After the formation of pneumoconiosis lesions, the residual dust in the lungs continues to interact with alveolar macrophages, causing pneumoconiosis patients to continue to develop lesions even though they are out of dust operations. [0003] In the 1970s, my country actively carried out drug screening r...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8969A61P11/00
Inventor 李云鹏王永郑淑艳
Owner HEBEI YILING MEDICINE INST
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