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Medicinal composition for treating infertility as well as preparation method and application of medicinal composition

A technology of composition and medicine, which is applied in the field of pharmaceutical composition for treating infertility and its preparation and use, can solve the problems of obvious toxic and side effects, serious physical damage, etc., and achieve the effects of low toxic and side effects, improving immunity and definite curative effect

Inactive Publication Date: 2014-07-30
SICHUAN SAINTHOOD BIOTECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] It is difficult to treat female infertility clinically. The current treatment methods are mainly Western medicine, usually supplementing estrogen drugs or surgery. Although there is a certain effect, it is harmful to the body and has obvious side effects

Method used

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  • Medicinal composition for treating infertility as well as preparation method and application of medicinal composition
  • Medicinal composition for treating infertility as well as preparation method and application of medicinal composition
  • Medicinal composition for treating infertility as well as preparation method and application of medicinal composition

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0034] The preparation method of embodiment 1 pharmaceutical composition of the present invention

[0035] prescription:

[0036] Rehmannia glutinosa 15kg, white peony 15kg, dogwood 15kg, yam 15kg, poria cocos 15kg, astragalus 20kg, codonopsis 20kg, epimedium 15kg, jujube 15kg.

[0037] Preparation:

[0038] Take various raw materials respectively, add water and decoct three times independently. Add water 6 times its weight for the first time, soak for 1 hour, then decoct for 2 hours; add water 5 times its weight for the second time, decoct for 1 hour; add water 4 times its weight for the third time, decoct After 1 hour, filter, combine the filtrates, heat and concentrate to a relative density of 1.09-1.12 at 60-65°C; spray the above-mentioned concentrated solution through a high-speed centrifugal spray dryer, and prepare dry powders of various raw materials of 80-120 mesh. Extract powder.

[0039] Various dry extract powders are mixed, and appropriate amount of filler is ...

Embodiment 2

[0040] Embodiment 2 The preparation method of pharmaceutical composition of the present invention

[0041]prescription:

[0042] Rehmannia glutinosa 15kg, white peony 15kg, dogwood 15kg, yam 15kg, poria cocos 15kg, astragalus 20kg, codonopsis 20kg, epimedium 15kg, jujube 15kg.

[0043] Preparation:

[0044] Take various raw materials, mix them, add water and decoct three times. Add water 6 times its weight for the first time, soak for 1 hour, then decoct for 2 hours; add water 5 times its weight for the second time, decoct for 1 hour; add water 4 times its weight for the third time, decoct After 1 hour, filter, combine the filtrates, heat and concentrate to a relative density of 1.09-1.12 at 60-65°C; spray-dry the above-mentioned concentrated solution by a high-speed centrifugal spray dryer, and prepare a dry extract powder of 80-120 mesh. The dry extract powder is added with an appropriate amount of filler to prepare capsules.

Embodiment 3

[0045] Embodiment 3 The preparation method of pharmaceutical composition of the present invention

[0046] prescription:

[0047] Rehmannia glutinosa 20kg, white peony root 10kg, dogwood 10kg, yam 10kg, poria cocos 10kg, astragalus 15kg, codonopsis 15kg, epimedium 10kg, jujube 10kg.

[0048] Preparation:

[0049] Various raw materials are taken, mixed, impregnated and extracted with 55-65% v / v ethanol, the extract is recovered from ethanol, concentrated, and appropriate amount of auxiliary materials are added to prepare tablets.

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Abstract

The invention provides a medicinal composition for treating infertility. The medicinal composition is prepared from the following raw medicinal materials in parts by weight: 10-20 parts of prepared rehmannia, 10-20 parts of radix paeoniae alba, 10-20 parts of dogwood, 10-20 parts of yam, 10-20 parts of poria, 15-25 parts of astragalus membranaceus, 15-25 parts of codonopsis pilosula, 10-20 parts of epimedium and 10-20 parts of Chinese date. The medicinal composition is precise and appropriate in compatibility and exact in curative effect. Experiments indicate that the composition is safe and reliable, and low in toxic and side effects, has remarkably improving effect on female infertility caused by androgen, oviduct inflammation, fallopian tube jam and other factors, can be used for remarkably increasing the pregnancy success rate of patients, improving immunity, and strengthening body fatigue resistance and anoxia resistance, thus providing a novel safe and reliable choice to clinical administration.

Description

technical field [0001] The invention relates to a pharmaceutical composition for treating infertility, its preparation method and application. Background technique [0002] In recent years, due to the influence of psychological, environmental, social and other factors, the fertility of couples of childbearing age in the world has been declining year by year, and most of the reasons are caused by the decline of female fertility. Female infertility is mainly caused by the following aspects: [0003] 1. Long-term endocrine disorders. Female endocrine disorders often manifest as symptoms such as amenorrhea, dysmenorrhea, low estrogen, menstrual cycle disorders, ovulation bleeding, and metabolic dysfunction. Behind this series of symptoms lie ovulation disorders, polycystic ovary syndrome, hyperprolactinemia, luteal phase insufficiency, ovarian insufficiency, premature ovarian failure and other diseases, which are important factors leading to infertility; [0004] Second, long...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8945A61P15/08A61P39/00A61P37/04
CPCA61K9/2068A61K9/4875A61K36/076A61K36/296A61K36/344A61K36/40A61K36/481A61K36/64A61K36/65A61K36/71A61K36/72A61K36/725A61K36/804A61K36/8945A61K2236/33A61K2236/331A61K2236/39A61P5/28A61P5/30A61P15/08A61P37/04A61P39/00A61K2300/00
Inventor 罗明锋郭小雪李改丽
Owner SICHUAN SAINTHOOD BIOTECH
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