Preparation of vaginal composite dressing and application thereof in treating gynecological diseases

A vaginal, uniform mixing technology, applied in the field of medical device manufacturing, to achieve the effect of improving vulva redness and inflammation

Inactive Publication Date: 2019-05-07
江西鼎中科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In the early stage of implantation, the vaginal composite dressing can guide the growth of probiotics and prevent the formation of pathogenic bacteria while inhibiting the formation; in the later stage of implantation, the vaginal composite dressing gradually degrades and covers the vaginal surface, ensuring the production of probiotics and inhibiting the growth of pathogenic bacteria. Function, there is no similar product on the market in the country at present

Method used

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  • Preparation of vaginal composite dressing and application thereof in treating gynecological diseases
  • Preparation of vaginal composite dressing and application thereof in treating gynecological diseases
  • Preparation of vaginal composite dressing and application thereof in treating gynecological diseases

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0030] A preparation method of a vaginal composite dressing, the specific preparation method comprising the following steps:

[0031] (1) Screening of raw and auxiliary materials: sieve lactose monohydrate, magnesium stearate, micronized silica gel, and povidone K30 respectively;

[0032] (2) Feeding: Feed according to the formula requirements according to the weight ratio;

[0033] (3) Mixing: The raw materials after feeding are mixed evenly in the stirring container;

[0034] (4) Granulation: The uniformly mixed powder is granulated by a granulator;

[0035] (5) Drying: the granules are dried with a dryer;

[0036] (6) Tablet compression: the dried granules are compressed with a tablet machine.

[0037] Further, in the step (1), the sieve used for sieving lactose monohydrate, magnesium stearate, micronized silica gel, and povidone K30 is 100 mesh;

[0038] Further, the parts by weight of each component fed in the step (2) are: 13 parts of lactose monohydrate, 83 parts of...

Embodiment 2

[0043] All the other are with embodiment 1,

[0044] Further, in the step (1), the sieve used for sieving lactose monohydrate, magnesium stearate, micronized silica gel, and povidone K30 is 120 mesh;

[0045] Further, the parts by weight of each component fed in the step (2) are: 11 parts of lactose monohydrate, 85 parts of magnesium stearate, 4 parts of micropowdered silica gel, and 4 parts of povidone K30;

[0046] Further, the mixing time in the step (3) is 40 min;

[0047] Further, the particles in the step (5) are dried to a moisture content of 4.0%;

[0048] Further, the weight of a single tablet after tableting in the step (6) is 0.9 g.

Embodiment 3

[0050] All the other are with embodiment 1,

[0051] Further, in the step (1), the sieve used for sieving lactose monohydrate, magnesium stearate, micronized silica gel, and povidone K30 is 80 mesh;

[0052] Further, the parts by weight of each component fed in the step (2) are: 12 parts of lactose monohydrate, 85 parts of magnesium stearate, 5 parts of micropowdered silica gel, and 2 parts of povidone K30;

[0053] Further, the mixing time in the step (3) is 50 min;

[0054] Further, the particles in the step (5) are dried to a moisture content of 3.0%;

[0055] Further, the weight of a single tablet after tableting in the step (6) is 0.6 g.

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PUM

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Abstract

The present invention discloses a preparation of a vaginal composite dressing and an application thereof in treating gynecological diseases. The preparation comprises the following technological processes: raw and auxiliary material screening, material feeding, mixing, granulating, drying, tableting, etc., and the product is obtained by the physical methods. Beneficial effects are as follows: theproduct produced by the manufacturing technology enables females to apply the dressing by a special treatment, thereby achieving a purpose of sustained release, keeping internal environment of vaginato be continuously constant and being conducive to growth of probiotics.

Description

technical field [0001] The invention relates to the field of medical device manufacturing, in particular to the preparation of a vaginal composite auxiliary material and its application in the treatment of gynecological diseases. Background technique [0002] The vagina is an elastic tube-shaped organ located between the bladder, urethra, and rectum. It has a variety of physiological functions in the process of human reproduction. It is the channel connecting the uterus and vulva, the only way to discharge menstrual blood and deliver babies, and it is also an important sexual organ. [0003] Physiological functions of the vagina: ①The channel that transports menstrual blood from the uterus to the outside of the body; ②An important place for women to have sex, the anterior wall of the lower vagina is particularly sensitive to sexual behavior; ③Under normal circumstances, the vagina is the channel through which the fetus is delivered from the mother ; ④ The vagina is a window...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K9/20A61K47/26A61P15/02A61P31/02A61P31/04A61P17/04A61P15/00A61L31/02A61L31/04A61L31/16
Inventor 沈奕吕再萍廖晓勇郭淑莲
Owner 江西鼎中科技有限公司
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