A kind of pharmaceutical composition for treating ulcerative colitis and application thereof
A kind of ulcerative colitis and composition technology, applied in the field of traditional Chinese medicine
- Summary
- Abstract
- Description
- Claims
- Application Information
AI Technical Summary
Problems solved by technology
Method used
Image
Examples
Embodiment 1
[0015] Example 1 Preparation of Dragon's Leaf Extract
[0016] Remove impurity, clean, pulverize and grind about 32 meshes. Weigh 10kg of the leaves powder and place it in a reflux extraction device. Add 85L of purified water to soak for 1 hour, then heat to reflux for 1 hour, and extract 2 times. The extracts were combined, concentrated under reduced pressure to 1.5 times (v / w) of the weight of the raw material of scorpion leaf, added with equal volume of ethyl acetate and extracted 3 times, combined the extracts, recovered the ethyl acetate and lyophilized with a freeze dryer, crushed, Delongia leaf extract.
Embodiment 2
[0017] Example 2 Preparation of Dragon's Leaf Extract
[0018] Remove impurity, clean, pulverize the leaves of dragon worms to a particle size of about 32 meshes, weigh 10 kg of powder of dragon worms leaves, place them in the extraction device, add 100L of purified water and soak for 1 hour, then heat and reflux for 1.5 hours, and extract 2 times. The extracts were combined, concentrated under reduced pressure to 1 time (v / w) of the weight of the raw material of scorpion leaf, added with an equal volume of ethyl acetate for extraction twice, combined the extracts, recovered the ethyl acetate and lyophilized with a freeze dryer, crushed, Delongia leaf extract.
Embodiment 3
[0019] Example 3 Therapeutic test study of the extract of serrata leaves on mice with ulcerative colitis
[0020] Forty healthy adult Kunming mice, male, weighing 20-24g, were randomly divided into the following 4 groups: blank control group, model control group, low-dose drug group, and high-dose drug group. The blank control group drank distilled water freely, and the other groups drank 5% dextran sodium sulfate aqueous solution freely for 6 days to create a mouse colitis model. During the modeling period, the blank control group and the model control group were intragastrically administered with normal saline every day; the low and high-dose drug groups were intragastrically administered with 50, 150 mg / kg Glycine max leaf extract daily (prepared in Example 1 of the present invention).
PUM
Abstract
Description
Claims
Application Information
- R&D Engineer
- R&D Manager
- IP Professional
- Industry Leading Data Capabilities
- Powerful AI technology
- Patent DNA Extraction
Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.
© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com