Faeces sample stabilizing solution, preparation method and application

Abstract

The invention relates to the field of molecular biology, and discloses a faeces sample stabilizing solution. The stabilizing solution comprises the following components: 0.02M-4M Guanidine thiocyanate, Tris-HCI of which the pH is 5-10 and the concentration is 2-20 M, 0.05-0.1 mM NaCl and 1-15 mM EDTA. According to the invention, the stability of the detected components in the faeces sample can be effectively kept, self-help fetch by a patient at home can be possible, the faeces stabilizing solution cannot be a hindrance to downstream detection (nucleic acid extraction and detection), the mixture of the faeces and the stabilizing solution can directly enter a detection process, greatly facilitates the flexibility of the follow-up treatment process of the faeces sample, and is beneficial to the detection and the treatment of digestive system diseases.

Description

technical field [0001] The invention relates to the field of molecular biology, in particular to a stool sample stabilization solution. Background technique [0002] At present, for stool tests in hospitals or physical examination centers, the samples cannot be preserved due to instability, and must be sent for examination immediately. This has caused certain inconvenience to patients, increased the workload of medical staff, and also increased the difficulty of operating and providing results in a timely manner for testing laboratories. Therefore, the proportion of patients who cooperate in providing samples decreases, which affects the effectiveness of subsequent related medical methods. Contents of the invention [0003] The purpose of the present invention is to provide a stool sample stabilization solution that can effectively maintain the stability of the detected components in the stool sample, is non-toxic or corrosive, does not hinder downstream detection, and is...

AI Technical Summary

Problems solved by technology

[0002] At present, for stool tests in hospitals or physical examination centers, samples cannot be preserved due to instability, and must be sent for testing immediately

This has caused some inconvenience to patients, increased workload for medical staff, and at the same time, also increased the difficulty for testing laboratories to operate and provide timely results.

Therefore, the proportion of patients who cooperate in providing samples decreases, which affects the effectiveness of follow-up related medical methods.

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