Vilazodone hydrochloride composition and preparation method thereof
A technology of vilazodone hydrochloride and a composition is applied in the directions of pharmaceutical combinations, pharmaceutical formulations, medical preparations of inactive ingredients, etc. Effectiveness in Solving Dissolution Problems
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Embodiment 1
[0031] Table 1 Vilazodone hydrochloride tablet / capsule preparation
[0032]
[0033] Preparation process: vilazodone hydrochloride is crushed to a particle size of 5 μm, mixed evenly with other excipients in the prescription, directly compressed into tablets or powdered and directly filled into capsules.
Embodiment 2
[0035] Table 2 Vilazodone hydrochloride tablet / capsule preparation
[0036]
[0037] Preparation process: Vilazodone hydrochloride is crushed to a particle size of 5 μm, mixed evenly with other excipients in the prescription except silicon dioxide and magnesium stearate, added with an aqueous solution of polysorbate 80 to granulate, dried and granulated, and then added with two Silicon oxide and magnesium stearate are mixed and compressed into tablets.
Embodiment 3
[0039] Table 3 Vilazodone hydrochloride tablet / capsule preparation
[0040]
[0041] Preparation process: vilazodone hydrochloride is mixed with lactose and beta-cyclodextrin, crushed to a particle size of 20 μm, mixed evenly with other excipients in the prescription, directly compressed into tablets or powdered into capsules.
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