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Application of ginseng and polygonum multiflorum compound polysaccharide in preparation of health foods with anti-aging effect

A polysaccharide and compound polysaccharide technology of Polygonum multiflorum, which is applied in the direction of polysaccharide/gum-containing food ingredients, multi-step food processing, application, etc., can solve the problems of limited action targets and insufficient active functions, and achieve anti-aging, simple and perfect preparation process, The effect of promoting in-depth application and modernization of traditional Chinese medicine

Inactive Publication Date: 2014-12-03
INFINITUS (CHINA) CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, due to the multifactorial, complex and latent nature of the occurrence and development of aging and related diseases, a single polysaccharide may have problems such as limited targets and insufficient activity and function. Therefore, expanding and enhancing the activity of polysaccharides is essential for further development and improvement Sugar products are essential

Method used

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  • Application of ginseng and polygonum multiflorum compound polysaccharide in preparation of health foods with anti-aging effect
  • Application of ginseng and polygonum multiflorum compound polysaccharide in preparation of health foods with anti-aging effect
  • Application of ginseng and polygonum multiflorum compound polysaccharide in preparation of health foods with anti-aging effect

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0036] A compound polysaccharide of ginseng and Polygonum multiflorum provided in this example is prepared by the following method: mixing ginseng and Polygonum multiflorum medicinal materials at a weight ratio of 1:1, wherein ginseng refers to the root of medicinal parts of ginseng, and Polygonum multiflorum refers to the root of Polygonum multiflorum. Root tubers of medicinal parts, the same below, after pulverization, add water according to the ratio of solid to liquid 1:10 (g / mL), heat and stir at 90°C for 4 hours for extraction. Add water to the medicinal dregs obtained by filtration according to the solid-liquid ratio of 1:5 (g / mL), and continue to extract at 90°C for 4h. Combine the two extracts, concentrate under reduced pressure and centrifuge to obtain a clear concentrated solution, add 4 times the volume of 95% (volume percentage, the same below) ethanol to the concentrated solution according to the volume ratio of 1:4, mix well and store at 4°C The precipitate was ...

Embodiment 2

[0040] A compound polysaccharide of ginseng and Polygonum multiflorum provided in this example is prepared by the following method: mixing ginseng and Polygonum multiflorum medicinal materials according to the weight ratio of 2:3, and adding water according to the ratio of solid to liquid after pulverization of 1:15 (g / mL), Heat and stir at 90°C for 6h. Concentrate under reduced pressure and centrifuge to obtain a clarified concentrated solution. Add 3 times the volume of 95% ethanol to the concentrated solution according to the volume ratio of 1:3, mix well and let it stand overnight at 4°C for precipitation, collect the precipitate by centrifugation, and vacuum freeze-dry to obtain Complex polysaccharides.

[0041] In this embodiment, as in Example 1, ginseng or Polygonum multiflorum can be used as raw materials to prepare ginseng and Polygonum multiflorum complex polysaccharides.

Embodiment 3

[0043] A compound polysaccharide of ginseng and Polygonum multiflorum provided in this example is prepared by the following method: mixing ginseng and Polygonum multiflorum medicinal materials according to the weight ratio of 3:2, after crushing, adding water according to the ratio of solid to liquid of 1:10 (g / mL), Extract by heating and stirring at 95°C for 3h. The medicinal dregs obtained by filtering are continuously extracted once according to the above-mentioned solid-liquid ratio, temperature and time. Combine the two extracts, concentrate under reduced pressure and centrifuge to obtain a clear concentrated solution, add 2 times the volume of 95% ethanol to the concentrated solution according to the volume ratio of 1:2, mix well and let it stand overnight at 4°C for precipitation, and collect the precipitate by centrifugation , the complex polysaccharide can be obtained after vacuum freeze-drying.

[0044] In this embodiment, as in Example 1, ginseng or Polygonum multi...

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Abstract

The invention discloses an application of a ginseng and polygonum multiflorum compound polysaccharide in preparation of health foods with an anti-aging effect. The compound polysaccharide is the ginseng and polygonum multiflorum compound polysaccharide which is prepared from ginseng and / or polygonum multiflorum by the processes of water extraction, concentration and alcohol precipitation. The compound polysaccharide disclosed by the invention is capable of effectively prolonging the average life of wild and oxidative stress models and protein aggregation toxic models through the verification of a caenorhabditis elegans model experiment, and the action way thereof is closely related to improvement of nematode antioxidant capacity, inhibition to toxic protein stress, enhancement of heat shock protein activity and adjustment of insulin signal pathway key nodes, thus indicating that the compound polysaccharide has good functions of delaying aging and preventing and treating the diseases related to aging.

Description

technical field [0001] The invention belongs to the technical field of health food / health food, and specifically relates to the application of a compound polysaccharide of ginseng and Polygonum multiflorum in preparing health food with anti-aging effect. technical background [0002] Modern studies have shown that aging is the result of a combination of internal and external stress factors, and these stress conditions and aging itself are also important factors in the pathological process of various diseases. For example, oxidative stress, toxic aggregated proteins are closely related to the aging of organisms and various diseases such as neurodegenerative diseases and tumors. Although aging is an inevitable natural law, it is possible to delay aging. As the problem of global population aging is becoming more and more serious, the incidence of aging-related diseases is also increasing year by year. In addition to using medical means to treat existing diseases and discomfor...

Claims

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Application Information

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IPC IPC(8): A23L1/09A61K31/715A61P39/06
CPCA23L29/30A23V2002/00A23V2250/2124A23V2250/21A23V2250/51A23V2300/38A23L33/105A61K8/9789A61K2800/92A61P39/06A61Q19/08
Inventor 胡明华梁明李海峰马方励
Owner INFINITUS (CHINA) CO LTD
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