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Glycine derivative having melanin production inhibition and whitening composition using same

A technology for inhibiting melanin and glycine, applied in cosmetic preparations, cosmetic preparations, preparations for skin care, etc., can solve problems such as manufacturing difficulties, discoloration, and pungent smell of products, and achieve the effect of improving stability

Active Publication Date: 2017-05-03
CORUM
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

(refer to the embodiment of U.S. Patent No. 6,801,050) yet, use sulfide as stabilizer and cause the product to have the problem of pungent smell easily (referring to the narration of US 6,020,367), so this method does not solve whitening formulation simultaneously for color and smell requirements and questions
[0007] Although arbutin has a whitening effect, because its structure is a glycosylated hydroquinone (Glycosylatedhydroquinone), it is still easy to change color due to the oxidation of aromatic phenol groups in the formula, which causes difficulties in formula manufacturing
In addition, the low solubility of arbutin in water leads to a low concentration in the formulation, and actually produces a low whitening effect (refer to Japanese Patent Application Laid-Open No. 2009-67691), proposed in Japanese Patent Laid-Open No. 2009-67691 Arbutin nano-dispersed particles are used, but it is difficult to manufacture, and the product is inconvenient to use, and there is still a problem that it is not easy to be absorbed by the skin

Method used

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  • Glycine derivative having melanin production inhibition and whitening composition using same
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  • Glycine derivative having melanin production inhibition and whitening composition using same

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Embodiment Construction

[0026] The aforementioned and other technical contents, features and effects of the present invention will be clearly presented in the following detailed description of a preferred embodiment with reference to the drawings. In order to provide a thorough understanding of the present invention, detailed steps and components thereof will be set forth in the following description. Obviously, the practice of the invention is not limited to specific details familiar to those skilled in the art. On the other hand, well-known components or steps have not been described in detail so as not to unnecessarily limit the invention. The preferred embodiments of the present invention will be described in detail as follows, but in addition to these detailed descriptions, the present invention can also be widely implemented in other embodiments, and the scope of the present invention is not limited, which is subject to the scope of the patents that follow .

[0027] The present invention rel...

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Abstract

The invention discloses a glycine derivate having a function of inhibiting melanogenesis. The glycine derivate has the following structure shown in a general formula (I) in the specification, wherein R1 represents C1 to C4 alkyl, R2 represents hydrogen atoms or methyl, and n represents an integer from 1 to 6. The glycine derivate can be used as an effective component for whitening skins and can be applied to various whitening formula compositions; moreover, the glycine derivate is high in stability and is particularly applied to water-based cosmetic care product formulas with transparent appearances.

Description

[0001] The present invention is a divisional application of the application number 201080002871.7, the title of the invention is "Glycine Derivatives with Inhibiting Melanin Production and Whitening Composition Using It", and the filing date of the original parent application is October 22, 2010 . technical field [0002] The present invention relates to a glycine derivative, in particular to a glycine derivative capable of inhibiting melanin production and a whitening composition using the same. Background technique [0003] Generally, the production mechanism of melanin is considered to be related to tyrosinase. In epidermal cells, tyrosine, the precursor of melanin, naturally exists in the melanin production reaction process through tyrosine → Dopa → Dopaquinone → Dopachrome → melanin , tyrosinase is an important enzyme that converts tyrosine into dopa through its hydroxylase activity, and converts dopa into dopaquinone through its oxidase activity. Therefore, as long a...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K8/42A61Q19/02
Inventor 徐乃璇徐巧宜王思晴陈婷菀庞菊宜
Owner CORUM
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