Application of GFP-30 protein and lipidosome in preparation protein medicine used for treating sound sensing nerve deafness and inherited deafness
Patent Information
- Authority / Receiving Office
- CN · China
- Current Assignee / Owner
- EYE & ENT HOSPITAL SHANGHAI MEDICAL SCHOOL FUDAN UNIV
- Publication Date
- 2015-01-21
- Estimated Expiration
- Not applicable · inactive patent
Smart Images
Figure 1 
Figure 2
Abstract
Description
technical field
[0001] The invention belongs to the technical field of biomedicine and relates to the application of GFP-30 protein and liposome in the preparation of protein medicine for treating sensorineural deafness or hereditary deafness Background technique
[0002] According to the data released by the World Health Organization, there are 250 million patients with moderate and severe deafness in the world. According to the second sample survey of disabled people in my country in 2006, the number of hearing disabled people in my country has reached 27.8 million, and it is still increasing. %. Due to the lack of damage repair and self-regeneration ability of inner ear hair cells and spiral nerves, the research on hair cell regeneration is very important. Recently, it has been reported that inner ear support cells express Atoh1 gene, which can make support cells transdifferentiate into hair cells, but this gene The expression of adenovirus is carried by adenovirus, and ...