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A pharmaceutical composition for treating arrhythmia coronary heart disease

A technology for arrhythmia and composition, applied in the directions of drug combination, drug delivery, cardiovascular system diseases, etc., can solve the problems of difficult popularization and application, high cost of interventional therapy, and high cost of treatment, and achieve the effect of high application value.

Inactive Publication Date: 2017-12-19
刘林强
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In addition, the cost of interventional treatment is high, so it limits its clinical application to a large extent.
In addition, other treatment methods, such as pacemaker, radiofrequency ablation, defibrillator and other invasive methods have certain effects, but the treatment cost is also relatively expensive, and many patients are unaffordable, so it is difficult to promote clinical application

Method used

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  • A pharmaceutical composition for treating arrhythmia coronary heart disease

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0015] The preparation of embodiment 1 Chinese medicine granules

[0016] Weigh 0.45kg of longan core, 0.25kg of glutinous rice root, 0.20kg of Houttuynia cordata, 0.25kg of upland grass, 0.11kg of cinnabar root, 0.07kg of blood residue charcoal, 0.07kg of Wujiapi, 0.07kg of magnolia officinalis, and 0.02kg of kansui , orange leaves 0.09kg, Xu Changqing 0.09kg, combined, add water to decoct twice, the volume of water added for the first time is 10 times the total mass of medicinal materials (L / kg), decocted for 2 hours; the volume of water added for the second time is the total mass of medicinal materials 8 times the amount (L / kg), decocted for 1.5h, combined the decoction, concentrated under reduced pressure at 0.08MPa and 70°C to a relative density of about 1.15 at 70°C, and added 95% (v / v) ethanol to make the alcohol-containing The amount reaches 75% (v / v), stir, stand overnight, filter, and the filtrate is concentrated under reduced pressure at 0.08MPa and 65°C to form an ...

Embodiment 2

[0017] The preparation of embodiment 2 Chinese medicine oral liquid

[0018] Weigh 0.50kg of longan core, 0.25kg of glutinous rice root, 0.25kg of Houttuynia cordata, 0.25kg of upland grass, 0.15kg of cinnabar root, 0.07kg of blood residue charcoal, 0.09kg of Wujiapi, 0.05kg of magnolia officinalis, 0.02kg of kansui , orange leaves 0.10kg, Xu Changqing 0.07kg, combined, add water to decoct twice, the volume of water added for the first time is 10 times the total mass of medicinal materials (L / kg), and decocted for 2 hours; the volume of water added for the second time is the total mass of medicinal materials 8 times the amount (L / kg), decocted for 1.5h, combined the decoction, concentrated under reduced pressure at 0.08MPa and 70°C to a relative density of about 1.15 at 70°C, and added 95% (v / v) ethanol to make the alcohol-containing The amount reaches 80% (v / v), stirred, left standing overnight, filtered, and the filtrate is concentrated under reduced pressure at 0.08MPa and ...

Embodiment 3

[0019] The preparation of embodiment 3 Chinese medicine oral liquid

[0020] Weigh 0.40kg of longan core, 0.21kg of glutinous rice root, 0.15kg of Houttuynia cordata, 0.21kg of upland grass, 0.10kg of cinnabar root, 0.08kg of blood residue charcoal, 0.06kg of Wujiapi, 0.05kg of magnolia officinalis, and 0.02kg of kansui , orange leaves 0.12kg, Xu Changqing 0.12kg, combined, add water to decoct twice, the volume of water added for the first time is 10 times the total mass of medicinal materials (L / kg), and decocted for 2 hours; the volume of water added for the second time is the total mass of medicinal materials 8 times the amount (L / kg), decocted for 1.5h, combined the decoction, concentrated under reduced pressure at 0.08MPa and 70°C to a relative density of about 1.18 at 70°C, added 95% (v / v) ethanol to make the alcohol-containing The amount reaches 78% (v / v), stirred, left standing overnight, filtered, and the filtrate is concentrated under reduced pressure at 0.08MPa and ...

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Abstract

The invention discloses a pharmaceutical composition treating arrhythmia coronary heart disease. The pharmaceutical composition is prepared from traditional Chinese medicinal materials and pharmaceutic adjuvants. The traditional Chinese medicinal materials comprises, in parts by weight, 39-56 parts of longan flower, 21-30 parts of root of glutinous rice, 15-25 parts of herba houttuyniae, 21-30 parts of lindernia ruellioides, 8-16 parts of radix ardisiae crenatae, 5-9 parts of crinis carbonisatus, 5-9 parts of cortex acanthopanacis, 5-9 parts of flos magnoliae officinalis, 1.5-3 parts of radix kansui, 7-12 parts of tangerine leaf, and 7-12 parts of radix cynanchi paniculati. The pharmaceutical composition has the effect obviously better than that of metoprolol and other western medicines after being used to treat arrhythmia coronary heart disease patients, and does not generate obvious adverse reaction or toxic and side effects during treatment, and is relatively safe.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicine, and in particular relates to a pharmaceutical composition for treating arrhythmia and coronary heart disease. Background technique [0002] Coronary heart disease is a group of clinical syndromes in which coronary artery stenosis caused by various reasons leads to ischemia and necrosis of the perfused myocardium. Coronary heart disease has a higher incidence rate in developed countries, so it is called the "number one killer". The disease is more common in middle-aged and elderly people, and the incidence rate has a gradual upward trend. According to the World Health Organization's forecast, by 2020, cardiovascular disease will become the world's leading cause of death. It can be seen that coronary heart disease has become one of the main diseases affecting the life, health and quality of life of middle-aged and elderly people. [0003] Coronary heart disease is a common c...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/899A61P9/10A61P9/06A61K35/36
CPCA61K9/0053A61K9/08A61K9/1652A61K35/36A61K36/185A61K36/254A61K36/27A61K36/47A61K36/575A61K36/752A61K36/77A61K36/78A61K36/80A61K36/899A61K2300/00
Inventor 刘林强王玲侯磊赵文霞刘茂月
Owner 刘林强
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