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Preparation and application of salicylic acid and chitosan compound composition

A technology of chitosan and compound composition, which is applied in the field of salicylic acid and chitosan compound composition and its preparation, and can solve problems such as difficulties in direct use

Active Publication Date: 2015-05-20
SHANGHAI JAHWA UNITED
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, it must be neutralized with dilute acid before it can be dissolved in water, so it is difficult to use directly

Method used

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  • Preparation and application of salicylic acid and chitosan compound composition
  • Preparation and application of salicylic acid and chitosan compound composition
  • Preparation and application of salicylic acid and chitosan compound composition

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0029] Embodiment 1: prepare the compound composition of salicylic acid and chitosan

[0030] The compound composition of salicylic acid and chitosan was prepared according to the components and contents shown in Table 1.

[0031] Table 1

[0032] substance

[0033] According to the preparation process, take 1.0g salicylic acid and 1.2g chitosan, add 15g ethanol, stir to dissolve and disperse, then add water to 100g. Dissolution was complete to obtain an acidic solution with a pH of 3.2.

Embodiment 2

[0034] Embodiment 2: prepare the compound composition of salicylic acid and chitosan

[0035] The compound composition of salicylic acid and chitosan was prepared according to the components and contents shown in Table 2.

[0036] Table 2

[0037] substance

[0038] According to the preparation process, take 1.0g salicylic acid and 1.8g chitosan, add 15g ethanol, stir to dissolve and disperse, then add water to 100g. Dissolution was complete to obtain an acidic solution with a pH of 3.4.

Embodiment 3

[0039] Embodiment 3: prepare the composite composition of salicylic acid and chitosan

[0040] The compound composition of salicylic acid and chitosan was prepared according to the components and contents shown in Table 3.

[0041] table 3

[0042] substance

[0043] According to the preparation process, take 1.0g salicylic acid and 1.2g chitosan (high molecular weight) and add 10% ethanol, stir to dissolve and disperse, then add water to 100g. Dissolution is complete to obtain an acidic solution with a pH of about 2.8.

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Abstract

The invention discloses a compound composition containing salicylic acid and chitosan, wherein the weight ratio of salicylic acid to chitosan is 1:1-1:1.8, and pH of the composition is 2.0-5.0. The invention further relates to a preparation method of the composition containing salicylic acid and chitosan, and application of the composition in cosmetics.

Description

technical field [0001] The invention relates to the fields of polymer chemistry and cosmetics, in particular to a compound composition of salicylic acid and chitosan, a preparation method and application thereof. Background technique [0002] Salicylic acid (Salicylic acid, referred to as SA), also known as o-hydroxybenzoic acid, is a white crystalline powder that exists in willow bark, white pearl leaves and sweet birch in nature. Salicylic acid can remove the accumulated thick stratum corneum and promote metabolism. In the field of medical cosmetology, SA has been recognized by everyone, especially for its special effects in lightening pigment spots, shrinking pores, removing acne, removing fine wrinkles and improving sun exposure. However, SA is a small molecular acid with strong permeability, which can stimulate deep skin and nerves. At the same time, salicylic acid has poor water solubility (0.22g / 100ml), so it is difficult to directly apply high-concentration salicyli...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/73A61K8/365A61Q19/00A61Q19/08A61Q17/04
Inventor 袁旻嘉沈珮琳董蕾蕾郭奕光郑赛华陈梅许文君
Owner SHANGHAI JAHWA UNITED
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