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External-use composition for treating vulva lichen sclerosus

A composition for external use, sclerosing technology, applied in drug combinations, medical preparations containing active ingredients, diseases, etc., can solve problems such as no therapeutic drugs found and unclear pathogenesis

Inactive Publication Date: 2015-07-01
SHANDONG UNIV QILU HOSPITAL
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

So far, its pathogenesis is still unclear, and no definite and effective treatment drug has been found.

Method used

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  • External-use composition for treating vulva lichen sclerosus
  • External-use composition for treating vulva lichen sclerosus
  • External-use composition for treating vulva lichen sclerosus

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0014] Take Fructus Cnidii 25g, Sophora flavescens 20g, Scutellaria baicalensis 20g, Fresh white skin 15g, Psoraleae 17g, Gardenia 15g, Angelica dahurica 15g, Raw licorice 10g, Raspberry 15g, Zihua Diding 20g, Chishao 17g, Comfrey 15g, Add 8 times and 8 times the amount of water to extract twice, each time for 2 hours, combine the filtrates, and concentrate to 1.05-1.10.

[0015] clinical information

[0016] The cases came from patients who attended the outpatient clinic of Traditional Chinese and Western Medicine and Gynecology of Qilu Hospital of Shandong University from June 2006 to June 2014. All patients excluded other vulvar and cervical diseases and systemic lesions, such as tumors, diabetes, autoimmune diseases, etc., and each case was finally confirmed by biopsy and confirmed by pathology before entering the group. Patients meeting the criteria were randomly divided into 2 groups, one group was the invention group, and one group was the western medicine group, 60 ca...

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PUM

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Abstract

The invention provides an external-use composition for treating vulva lichen sclerosus. The external-use composition for treating the vulva lichen sclerosus is prepared from the following raw materials by weight: 25g of common cnidium fruit, 20g of light yellow sophora root, 20g of baikal skullcap root, 15g of densefruit pittany root-bark, 17g of malaytea scurfpea fruit, 15g of cape jasmine fruit, 15g of dahurian angelica root, 10g of raw liquorice root, 15g of palmleaf raspberry fruit, 20g of herba violae, 17g of red paeony root and 15g of root of sinkiang arnebia. The external-use composition can release pruritus vulvae symptom of patients, causes the color of vulva to recover the normal color, and shortens a pathological change range.

Description

technical field [0001] The invention relates to a medicine for treating lichen sclerosus of vulva, in particular to an external composition prepared from Chinese herbal medicine for treating lichen sclerosus of vulva. Background technique [0002] Lichen sclerosus of the vulva, as a common and refractory disease in gynecology and dermatology clinics, is a group of chronic inflammatory diseases, manifested as degeneration of vulvar skin and mucous membranes, and local pigment changes. The most common symptom of this disease is intractable genital itching, which is obvious when falling asleep, and often affects sleep because of the unbearable itching. As the disease progresses in some patients, atrophy of the clitoris and the vaginal opening and then adhesions occur, causing poor urination, dyspareunia, scratching due to severe itching, chapped and ulcers on the local skin, which seriously affect the quality of life of the patients. The main lesion characteristics of this...

Claims

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Application Information

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IPC IPC(8): A61K36/86A61P15/00
Inventor 武志红武志华巩克波李淑玲刘凯周靖巩丽王玖玲张潇丹
Owner SHANDONG UNIV QILU HOSPITAL
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