Traditional Chinese medicine composition for regulating chronic hepatitis B, decoction and application thereof
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A chronic hepatitis B, composition technology, applied in the field of medicine, can solve the problem of lack of specific immunotherapy for hepatitis B, and achieve the effect of effectively regulating Treg cells
Active Publication Date: 2015-08-19
JIANGSU PROVINCIAL HOSPITAL OF TCM
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[0008] In 2010, China's "Guidelines for the Prevention and Treatment of Chronic Hepatitis B" pointed out that immunomodulatory therapy is expected to become an important means of treating chronic hepatitis B, but there is still a lack of specific immunotherapy for hepatitis B with definite curative effect
The efficacy of immunomodulatory drugs still needs to be verified by large-sample randomized controlled clinical studies
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Embodiment 1
[0035] Example 1 Preparation of Chinese medicinal water decoction.
[0036] Traditional Chinese medicine formula: 15g of raw astragalus, 10g of flavescens, 15g of fried yam, 10g of Ligustrum lucidum, 10g of dodder, 10g of Smilax smilax, 10g of turmeric, 15g of Polygonum cuspidatum, 15g of phylloxera, and 10g of salvia miltiorrhiza.
[0037] Add appropriate amount of water to the above Chinese medicine formula, decoct twice, combine the filtrates twice to make 400ml water decoction.
Embodiment 2
[0038] The preparation of embodiment 2 Chinese medicinal water decoction.
[0039] The preparation method is the same as in Example 1, except that the traditional Chinese medicine formula is as follows: 12g of raw astragalus, 12g of flavescens, 12g of fried yam, 12g of Ligustrum lucidum, 8g of dodder, 12g of Smilax cocos, 8g of turmeric, 18g of Polygonum cuspidatum, and 12g and Danshen 12g.
Embodiment 3
[0040] The preparation of embodiment 3 Chinese medicinal water decoction.
[0041] The preparation method is the same as in Example 1, except that the traditional Chinese medicine formula is as follows: 18g of raw astragalus, 8g of flavescens, 16g of fried yam, 8g of privet lucidum, 12g of dodder, 8g of smilax, 12g of turmeric, 12g of Polygonum cuspidatum, and 18g and Danshen 8g.
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Abstract
The invention discloses a traditional Chinese medicine composition for regulating chronic hepatitis B. The traditional Chinese medicine composition comprises the following components in parts by weight: 10-20 parts of raw astragalus, 5-15 parts of radix sophorae flavescentis, 10-20 parts of fried Chinese yams, 5-15 parts of glossy privet fruits, 5-15 parts of semen cuscutae, 5-15 parts of rhizoma smilacis glabrae, 5-15 parts of radix curcumae, 10-20 parts of polygonum cuspidatum, 10-20 parts of underleaf pearls and 5-15 parts of salvia miltiorrhiza. The invention also provides application of the composition to preparation of a drug for treating chronic hepatitis B and regulating peripheral blood Treg cells. Concretely, the invention provides a decoction prepared according to the traditional Chinese medicine formula and application of the decoction to preparation of a drug for treating chronic hepatitis B by matching with a western drug. As a whole, the traditional Chinese medicine composition prepared according to the whole formula has the effects of tonifying the spleen and benefiting the kidneys as well as removing heat from the liver and dispersing blood stasis; and when being united with the western drug for treating chronic hepatitis B, the traditional Chinese medicine composition can be used for effectively regulating the peripheral blood Treg cells and is beneficial to the treatment of chronic hepatitis B.
Description
technical field [0001] The invention belongs to the field of medicine, and in particular relates to a traditional Chinese medicine composition for regulating chronic hepatitis B, a water decoction and an application thereof. Background technique [0002] World Health Organization statistics: about 350 million people in the world are chronically infected with hepatitis B virus (HBV), and about 1 million people die every year from liver failure, liver cirrhosis and liver cancer caused by HBV infection. The national epidemiological survey of hepatitis B shows that the positive rate of hepatitis B surface antigen (HBsAg) in the general population in my country is 7.18%. There are about 93 million people with chronic HBV infection in my country, including about 20 million chronic hepatitis B patients. Chronic hepatitis B has become a disease seriously affecting national health. [0003] The treatment of chronic hepatitis B mainly includes anti-virus, immune regulation, anti-infl...
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