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Medical sterilization ultrasound coupling agent and preparation method thereof

An ultrasonic couplant, medical technology, applied in echo/ultrasonic imaging agent and other directions, can solve the problems of skin irritation, ultrasonic energy loss, damage to the probe, etc., to achieve the effect of easy operation and simple method

Inactive Publication Date: 2015-09-09
长春呈实健康实业有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Poor quality couplant can cause loss of ultrasonic energy, lower resolution, blurred images, and even irritate the skin and damage the probe

Method used

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  • Medical sterilization ultrasound coupling agent and preparation method thereof
  • Medical sterilization ultrasound coupling agent and preparation method thereof
  • Medical sterilization ultrasound coupling agent and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

specific Embodiment approach 1

[0016] Specific embodiment one: the traditional Chinese medical disinfection ultrasonic coupling agent of this embodiment is made from the following raw materials:

[0017] Carbomer: 350g, glycerin: 5000g, sodium hydroxide: 100g, methyl benzoate: 100g, 95% ethanol, and purified water are added to 100L, and the mass ratio of the methyl benzoate to 95% ethanol is 10: 100; its preparation method is carried out according to the following steps:

[0018] Step 1, adding methyl benzoate into 95% ethanol and stirring until completely dissolved to obtain mixed solution A;

[0019] Step 2, then add carbomer, glycerin, and mixed solution A into 1000mL of purified water, stir until completely dissolved, and let stand for 12 hours to obtain mixed solution B;

[0020] Step 3: Add sodium hydroxide to 1000mL of purified water at a temperature of 35°C, then slowly add to the mixture B, stir for 30 minutes, then add purified water to make up to 100L, and then stir until the mixture is uniform;...

specific Embodiment approach 2

[0027] Specific embodiment two: the traditional Chinese medicine disinfection ultrasonic coupling agent of this embodiment is made of following raw materials:

[0028] Carbomer: 250g, glycerin: 3200g, sodium hydroxide: 95g, methyl benzoate: 80g, 95% ethanol, and purified water are added to 100L, and the mass ratio of the methyl benzoate to 95% ethanol is 8: 100.

[0029] The preparation method of the medical disinfection ultrasonic coupling agent in this embodiment is the same as that in the first embodiment.

[0030] The performance index of the product of this embodiment is shown in Table 2

[0031] Table 2

[0032]

[0033]

[0034] It can be seen from Table 2 that the product of this embodiment is sterile and has a disinfection effect; and it has no irritation to the skin and mucous membranes, no sensitization, and 0-level cytotoxicity.

specific Embodiment approach 3

[0035] Specific embodiment three: the present embodiment traditional Chinese medical disinfection ultrasonic coupling agent is made from the following raw materials:

[0036] Carbomer: 300g, glycerin: 3500g, sodium hydroxide: 98g, methyl benzoate: 85g, 95% ethanol, and purified water added to 100L, the mass ratio of said methyl benzoate to 95% ethanol is 10: 100.

[0037] The preparation method of the medical disinfection ultrasonic coupling agent in this embodiment is the same as that in the first embodiment.

[0038] The performance index of the product of this embodiment is shown in Table 2

[0039] table 3

[0040]

[0041]

[0042] It can be seen from Table 3 that the product of this embodiment is sterile and has a disinfection effect; and it has no irritation to the skin and mucous membranes, no sensitization, and 0-level cytotoxicity.

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Abstract

The invention discloses a medical sterilization ultrasound coupling agent and a preparation method thereof and belongs to the field of ultrasound coupling agent. The medical sterilization ultrasound coupling agent has the sterile and sterilizing functions and is prepared through carbomer, glycerine, sodium hydroxide, methyl benzoate, 95% ethanol and purified water. The method includes 1, adding methyl benzoate into 95% ethanol, stirring till dissolving completely, and obtaining a mixed solution A; 2, adding the carbomer, glycerine and mixed solution A into 1000mL purified water, stirring till dissolving completely, standing for 12 hours, and obtaining a mixed solution B; 3, adding the sodium hydroxide into the 1000mL purified water of the temperature of 30 to 40 DEG C, adding into the mixed solution B slowly, stirring for 30 minutes, adding the purified water till 100L, and stirring till being mixed evenly; obtaining the medical sterilization ultrasound coupling agent. The medical sterilization ultrasound coupling agent is applied to operations, ICU, burn and scald, external injury and other sterile environments and human body natural orifice ultrasound operations.

Description

technical field [0001] The invention belongs to the field of ultrasonic coupling agent. Background technique [0002] During ultrasound examination, the air between the probe and the patient's skin will hinder the transmission of ultrasonic waves into the human body. In order to obtain high-quality images, a liquid conductive medium is needed to connect the probe and the patient's body surface. This medium is the couplant. [0003] The purpose of using an ultrasonic coupling agent is firstly to fill the tiny gaps between the contact surfaces, so that the tiny amount of air in these gaps does not affect the penetration of ultrasound; secondly, through the "transition" effect of the coupling agent, the acoustic impedance between the probe and the skin The difference is reduced, thereby reducing the reflection loss of ultrasonic energy at this interface. In addition, it also plays the role of "lubrication", reducing the friction between the probe surface and the skin, so that ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K49/22
Inventor 佟黎明佟乐
Owner 长春呈实健康实业有限公司
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