Chemical medical adhesive composition and preparation method thereof

A technology of adhesives and compositions, applied in surgical adhesives, applications, medical science and other directions, can solve the problems of insufficient bonding strength and difficulty in defects, etc.

Inactive Publication Date: 2015-10-07
SHAANXI BOYU REGENERATIVE MEDICINE CO LTD
View PDF4 Cites 27 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0007] In view of the deficiencies in the prior art, the purpose of the present invention is to overcome the disadvantages caused by quality control during the preparation of existing medical adhesives; and the shortcomings of limited in vi...

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Chemical medical adhesive composition and preparation method thereof
  • Chemical medical adhesive composition and preparation method thereof
  • Chemical medical adhesive composition and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment

[0026] The following examples will further illustrate the present invention, but are not intended to limit the scope of the present invention. Any modifications and changes made by those skilled in the art without departing from the spirit of the present invention are within the scope of the present invention.

[0027] Prepare composition (1) according to the chemical medical adhesive preparation method of the present invention, concrete steps are as follows: in dry box (water content≤1ppm, oxygen content≤1ppm, inert gas), with α-cyanoacrylic Butyl is 100 parts by weight. First, 20 parts of n-butyl α-cyanoacrylate, 2.5 parts of tackifier poly-a-n-butyl cyanoacrylate, and 1.5 parts of plasticizer tri-n-butyl citrate are added. Soak in 0.5M dilute sulfuric acid and wash, then stir and mix for 45 minutes in the glass container after high temperature sterilization at 40°C and 120r / min, then add 0.01 part of p-methoxyphenol and 0.05 part of p-toluenesulfonic acid as stabilizers, Pe...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

PUM

No PUM Login to view more

Abstract

The invention relates to a chemical medical adhesive composition and a preparation method thereof. The composition is composed of cyanoacrylate, plasticizer, tackifier, stabilizer and other aids. The chemical medical adhesive composition can be quickly polymerized under the initiation of negative ions and produce the adhesive capacity, has high adhesive strength, releases low heat during adhering and has good environment-friendly performance, and adhesive membranes can be degraded and completely excreted out of the body. Therefore, the biodegradable medical adhesive can be used for various wound adhesion, large-area wound hemostasis, closure of internal organ and soft tissue wounds, and is convenient to use.

Description

technical field [0001] The invention relates to the field of medical polymer materials, in particular to a biodegradable chemical medical adhesive composition and a preparation method thereof. Background technique [0002] Medical adhesive is a branch of medical polymer. It takes biological tissue as the bonding object. Most of the tissues and organs of the human body can be replaced by adhesive technology during the treatment process, without anesthesia; wound healing After that, it will fall off automatically. The medical adhesive itself is sterile and has antibacterial effect, so infection rarely occurs. Because of its remarkable curative effect on certain diseases, its unique characteristics and convenient operation, it is welcomed by clinicians. [0003] At present, medical adhesives play a very important role in clinical practice. They have been widely used in human tissues as adhesives, hemostatic agents, sealants, and embolic agents. A large number of basic experime...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

Application Information

Patent Timeline
no application Login to view more
IPC IPC(8): A61L24/04A61L24/06
Inventor 仇智丽
Owner SHAANXI BOYU REGENERATIVE MEDICINE CO LTD
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Try Eureka
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap