Pre-Column Derivatization Instruments for Ion Chromatography

Abstract

The invention discloses a precolumn derivatization instrument of ion chromatography. The instrument comprises a liquid phase solution, a pump, a reaction device, a sample injector, an incubator chromatography column and a detector which are sequentially connected. The reaction device comprises a shell, a reaction chamber and a temperature control unit. The reaction chamber is arranged in the shell. One end of the reaction chamber is communicated with the pump, and the other end of the reaction chamber is communicated with the sample injector. A heat preservation layer is arranged on the outer wall of the reaction chamber. The temperature control unit comprises a temperature control panel and a temperature control circuit board. A groove for containing the temperature control panel is formed in the bottom end face of the reaction chamber. The temperature control panel is fixed into the groove and controls the temperature of the reaction chamber. The control over the temperature and reaction time is strong, and derivatization efficiency is high.

Description

technical field [0001] The invention relates to the technical field of chemical derivatization, in particular to a pre-column derivatization instrument of ion chromatography. Background technique [0002] Derivatization is the use of chemical transformations to convert compounds into similar chemical structures. In general, a specific functional compound participates in the derivatization reaction, and the solubility, boiling point, melting point, aggregation state or chemical composition will be deviated. The resulting new chemical properties can be used for quantification or isolation. The role of sample derivatization is mainly to convert difficult-to-analyze substances into substances with similar chemical structures but easy to analyze, which is convenient for quantification and separation. When the detection substance is not easy to be detected, such as no ultraviolet absorption, etc., it can be processed, such as adding a chromophore, etc., to generate a detectable ...

AI Technical Summary

Problems solved by technology

The disadvantages are: the formed by-products may cause great difficulty in chromatographic separation; during the derivatization process, it is easy to introduce impurities or interference peaks, or cause sample loss

The disadvantages are: additional equipment is required, and the requirements for the instrument are relatively high; the reactor can cause peak broadening and reduce resolution; excessive reagents will cause interference

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