Quality detection method for traditional Chinese medicine formula

Abstract

A quality detection method for a traditional Chinese medicine formula which is named compound detoxication decoction. In the quality detection method, ultra performance liquid chromatography (UPLC) is employed for simultaneously detecting the contents of astilbin, forsythiaside A and forsythin in the compound detoxication decoction at 275 nm. According to the method, the various active components in the compound detoxication decoction are detected through the UPLC. The method is ultrahigh in separation rate, speed and sensitivity on the astilbin, the forsythiaside A and the forsythin. The method can achieve excellent chromatographic peak separation rate just through one injection without complex pre-treatment processes to a sample, so that the method is greatly increased in chromatographic separation rate and analysis speed, effectively saves analysis time, achieves quick and high-resolution quality detection for the compound detoxication decoction, and has excellent effects on clinical quality control.

Description

Technical field [0001] The invention relates to a traditional Chinese medicine prescription, in particular to a quality detection and analysis method of the traditional Chinese medicine prescription. Background technique [0002] The prescription of the Chinese medicine involved in the present invention is a prescription agreed by the 302nd Hospital of the People’s Liberation Army. The current name is Fufang Baidu Decoction, which is made up of 50~70g of roasted Astragalus; 45~65g of Smilax glabra; 55~75g of Radix eargrass; 40~60g of Forsythia Rhodiola 5~20g, of which Astragalus is the dried root of Astragalus mongolicus or Astragalus membranaceus, a perennial leguminous herb; Smilax glabra is the dried rhizome of Liliaceae perennial climbing vine Smilax glabra; Ground eargrass is Hypericum The dry whole plant of the annual herb Auranthus chinensis; Forsythia is the dry fruit of the Oleaceae deciduous shrub Forsythia; Rhodiola is the dry rhizome of the perennial herb of the Crass...

AI Technical Summary

Problems solved by technology

[0003] However, for Compound Baidu Decoction, if the commonly used HPLC technology is used, it is found that the chromatographic peaks of the complex components in the compound cannot be separated at all. Satisfactory chromatographic peak resolution cannot be obtained, so it is necessary to find other suitable analytical methods to achieve the technical purpose of simultaneously determining the main medicinal components in Compound Baidu Decoction, and to achieve rapid, high-speed, and high-sensitivity determination And the technical effect of the determination method is simple and easy

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