Use of 3-carboxy-n-ethyl-n,n-dimethylpropan-1-ammonium or a pharmaceutically acceptable salt thereof in the prevention and treatment of diabetes

A technology for dimethylpropane and diabetes, applied to the use of 3-carboxy-N-ethyl-N,N-dimethylpropane-1-ammonium or its pharmaceutically acceptable salt in the prevention and treatment of diabetes areas that can address issues such as inadequate insulin control
CN105530929BActive Publication Date: 2018-03-02GRINDEKS
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
GRINDEKS
Publication Date
2018-03-02

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Abstract

The present invention relates to the use of 3-carboxy-N-ethyl-N,N-dimethylpropan-1-ammonium and pharmaceutically acceptable salts thereof for reducing plasma insulin and glucose levels.
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Description

technical field

[0001] The present invention relates to 3-carboxy-N-ethyl-N,N-dimethylpropan-1-ammonium or a pharmaceutically acceptable salt thereof for preventing and treating diabetes. Examples of pharmaceutically acceptable salts of 3-carboxy-N-ethyl-N,N-dimethylprop-1-ammonium are: 3-carboxy-N-ethyl-N,N-dimethylpropane- 1-Ammonium hydrogen fumarate and 3-carboxy-N-ethyl-N,N-dimethylprop-1-ammonium dihydrogen phosphate. Background technique

[0002] It is known that 3-carboxy-N,N,N-trimethylpropan-1-ammonium (GBB) is mainly a biological precursor of carnitine, a key molecule regulating myocardial energy metabolism. It was initially characterized as a toxic substance that accelerates respiration, causes salivation and lacrimation, mydriasis, vasoconstriction and diastolic cardiac arrest (LINNEWEH W. Gamma-Butyrobetain, Crotonbetain und Carnitin im tierischen Stoffwechsel. Hoppe-Seylers Zeitschrift fur physiologische Chemie. 1929, vol. 181, p. 42-53). In subsequent publ...

Claims

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