Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Treatment of ventricular arrhythmias through combination of potassium aspartate and amiodarone

A technology for ventricular arrhythmia and potassium aspartate, which can be used in drug combinations, cardiovascular system diseases, etc., and can solve problems such as not inhibiting left ventricular function.

Inactive Publication Date: 2016-06-29
LIAONING YAOLIAN PHARMA
View PDF1 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Intravenous injection has mildly negative inotropic effects, but usually does not depress LV function

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Examples

Experimental program
Comparison scheme
Effect test

Embodiment

[0005] All 65 cases met the WHO diagnostic criteria for coronary heart disease. There were 39 males and 26 females; the age ranged from 38 to 65 years, with an average of 52.1 years; the disease duration was 0.4 to 2.8 years, with an average of 1.5 years. They were randomly divided into two groups, 33 cases in the treatment group and 32 cases in the control group. There was no significant difference in gender, age, course of disease, and severity of VA between the two groups, and they were comparable.

[0006] Treatment methods: All patients were treated with nitrates and other conventional treatments, and the control group was treated with amiodarone alone; the treatment group was treated with potassium aspartate (Liaoning Yaolian Pharmaceutical Co., Ltd.) on the basis of the control group. Production, correspondingly containing K + 114 × 4 mg, Mg2 + 4.2 × 4 mg) 40 mL was added to 5% glucose solution or normal saline for intravenous drip, once a day, 3 weeks as a course of tr...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

Potassium aspartate combined with amiodarone was used to treat ventricular arrhythmia in coronary heart disease, and the curative effect was satisfactory.

Description

technical field [0001] The invention relates to a potassium supplement injection for treating ventricular arrhythmia, in particular to a method for treating ventricular arrhythmia by injecting active ingredients potassium salt and amiodarone into the body, and belongs to the field of pharmaceutical preparations . Background technique [0002] It is a class III antiarrhythmic drug. A mildly noncompetitive alpha and beta adrenergic blocker. And with mild class I and IV antiarrhythmic properties. The main electrophysiological effect is to prolong the action potential and effective refractory period of various myocardial tissues, which is beneficial to eliminate the reentrant excitation. Inhibits the rapid influx of sodium ions in the conduction fibers of the atrium and myocardium, and slows down the conduction velocity. Decreases sinoatrial node self-discipline. No effect on resting membrane potential and action potential height. The inhibition of forward conduction of th...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/343A61P9/06A61K31/198
Inventor 于航李重琦
Owner LIAONING YAOLIAN PHARMA
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com