The invention provides a preparation method of a
potassium aspartate
crude drug. The preparation method specifically comprises the following steps: (a), adding proper amount of
purified water into a liquor preparation tank, adding a
potassium salt under stirring, adding
aspartic acid in a fractional manner while stirring after all
potassium salt is dissolved, and reacting under stirring; (b), detecting that a pH value is between 5.8-8.2, and regulating by using proper amount of the potassium salt or
aspartic acid if the detected value deviates from 5.8-8.2; (c), adding
medicinal charcoal and stirring for 20 minutes-30 minutes; (d), enabling medical liquor to pass through a
decarburization filter, filtering by a 0.45-mu m filter, monitoring and recording that pressure of the 0.45-mu m filter is between a range of 0.15 MPa-0.2 MPa, adding the
purified water into the liquor preparation tank after the medical liquor is filtered out, feeding filtrate into a
buffer tank by once to twice, and clarifying the filtrate; (e), spray-
drying, discharging and sub-packaging.