44 results about "Medicinal charcoal" patented technology

The invention discloses a pharmaceutical composition of fasudil hydrochloride for injection. The fasudil hydrochloride injection is composed of fasudil hydrochloride, cysteine ​​hydrochloride and sodium chloride, each containing hydrochloric acid method Sudil 15-60mg, cysteine ​​hydrochloride mg, sodium chloride mg. The preparation method is as follows: take 90% of the prescribed amount of water for injection, at a temperature of 55-65°C, add the prescribed amount of cysteine ​​hydrochloride, stir to dissolve; add the prescribed amount of fasudil hydrochloride, stir until dissolved, and pour into Then add the sodium chloride of recipe quantity in the solution, stir until dissolving completely; Measure initial pH value, according to initial pH value, adjust pH value range with 4% sodium hydroxide solution and 10% cysteine ​​hydrochloride solution in 5.5- 6.5; add medicinal charcoal to the mixture, stir; suction filter, add water for injection to the full amount, mix evenly; fine filter; fill; sterilize; The pharmaceutical composition of fasudil hydrochloride has good light stability, no crystallization and clarity, and good stability. The invention has the advantages of improving product yield, reducing cost, realizing industrialization, and better clinical application. more obvious advantages.

The invention provides a coenzyme A for injection and a production process thereof. The coenzyme A for injection consists of a coenzyme A, mannitol, dextran-40, calcium gluconate, sodium bisulfite, medicinal charcoal and fresh water for injection. The production process comprises the following steps of: adding the dextran-40, mannitol and calcium gluconate into the water for injection for dissolving, adding the medicinal charcoal, and cooking to boiling state; filtering and decarburizing the solution with a titanium stick, and filtering; mixing a sodium bisulfite aqueous solution with the filtered and decarburized solution, regulating the pH value with hydrochloric acid, replenishing the water for injection for preparing, and filtering with a microporous filtering film to obtain a coenzyme A solution for injection; and pre-freezing the coenzyme A solution for injection, subliming and drying to obtain a coenzyme A freeze-dried powder injection. In a preparation method, a freeze drying process is improved, the freeze drying time is shortened, and the production efficiency is increased greatly. The obtained freeze-dried powder injection has plump appearance, a clarified solution and high product content stability, and is quickly dissolved in water.

The invention discloses a pregnant sow feed for control of diarrhea and a producing method thereof, and the pregnant sow feed comprises the following raw materials by weight: 150-180 parts of barley protein powder, 140-160 parts of corn flour, 120-160 parts of wheat bran, 8-12 parts of herseconvolvuli linnaeus chrysalis powder, 10-15 parts of herse convolvuli chrysalis powder, 2-3 parts of radix puerariae, 1-2 parts of scutellaria baicalensis, 1-2 parts of coptis chinensis, 1-2 parts of radix paeoniae alba, 1-2 parts of prepared rhizome of rehmannia, 0.5-1 part of garlic, 0.5-1 part of raw ginger, 8-15 parts of chicken liver, 0.5-1 part of fish meat, 7-9 parts of green pepper, 1-2 parts of coriander, 2-3 parts of soy sauce, 0.5-1 part of vinegar, 10-14 parts of yellow rice, 8-13 parts of sago, 2-4 parts of mango dices, 1-2 parts of grape flesh, 1-3 parts of coptis chinensis leaf, 1-3 parts of emulsified fat, 4-8 parts of diatomite, 5-10 parts of talcum powder, 4-8 parts of medicinal charcoal, 1-2 parts of calcined oyster powder, 1-2 parts of calcined dragon bone powder, 10-15 parts of a food attractant, and proper amount of water. The pregnant sow feed effectively reduces economic loss of farmers.

The invention provides a production process of a zoledronic acid injection. The production process comprises the following steps of (1) preparing an osmotic pressure regulating agent solution: dissolving a prescription amount of an osmotic pressure regulating agent by water for injection, adding medicinal charcoal, and performing decarbonization to obtain the osmotic pressure regulating agent solution; (2) preparing a zoledronic acid and pH regulating agent solution: dissolving a prescription amount of zoledronic acid and a pH regulating agent by the water for injection to obtain the zoledronic acid and pH regulating agent solution; (3) preparing a prescription solution: uniformly mixing the obtained osmotic pressure regulating agent solution and the zoledronic acid and pH regulating agentsolution, dissolving the solution to a constant volume of a prescription volume by using the water for injection, and performing filtration to obtain the zoledronic acid prescription solution with apH value being 6.2 to 6.8; and (4) performing sterilization and packaging: taking the zoledronic acid prescription solution obtained in the step (3), and performing sterilization and packaging to obtain the zoledronic acid injection. The production process of the zoledronic acid injection provided by the invention has the advantages that the stability is high; work procedures are simple; the production efficiency is high; the quality is controllable; and the industrialization can be easily realized.

The invention discloses a method for preparing Sparfloxacin. The method comprises the steps of sequentially adding cis-2,6-dimethylpiperazine, 5-amino-1-cyclopropyl-6,7,8-trifluoro-1,4-dihydro-4-oxo-3-quinoline carboxylic acid and an aprotic polar solvent into a reaction tank according to a feeding ratio, performing a condensation reaction so as to obtain a wet crude product of Sparfloxacin, carrying out baking on the wet crude product of Sparfloxacin so as to control the water content of the wet crude product of Sparfloxacin, adding the dried Sparfloxacin crude product, an alkaline aqueous solution, water, hydrochloric acid, EDTA and medicinal charcoal into a reaction tank according to a feeding ratio, carrying out heating and stirring, carrying out cooling after dissolving is completed, carrying out discharging, centrifuging and spin-drying so as to obtain a wet Sparfloxacin product, subjecting the wet Sparfloxacin product to drying and performing crushing, thereby obtaining a finished product. As a whole, the method has the advantages that the product is good in stability and easy to treat in medicine processing, and the preparation process is simple.

The invention relates to a traditional Chinese preparation for treating acute haemorrhagia apoplexy, the process for preparation and use thereof, wherein the preparation comprises astragalus root, dried rehmannia root, achyranthes root, F68, medicinal charcoal, 95% ethanol, and water for injection.

The invention discloses an ibuprofen medicine composition for injection, which consists of ibuprofen and arginine glutamate, and is characterized in that the weight ratio of the ibuprofen to the arginine glutamate is 1:1.44. A preparation method of the medicine composition comprises the following steps of: taking injection water with weight being 70 percent of prescribed dosage, adding the arginine glutamate with prescribed dosage at 70-80DEG C, and agitating the mixture for dissolution; adding the ibuprofen with prescribed dosage and agitating the mixture till the ibuprofen is fully dissolved; adding medicinal charcoal into the solution, evenly agitating the mixture and standing the mixture; conducting suction filtration, replenishing the injection water to full dosage and evenly mixing the solution; determining the initial PH (potential of hydrogen) value, and regulating the pH value to 7.7 plus or minus 0.2 by using 4% sodium hydroxide solution and 10% hydrochloric acid solution according to the initial pH value; conducting refined filtration and filling; conducting sterilization; conducting lamp inspection; and warehousing the product to obtain the finished product. The ibuprofen medicine composition has high light stability, is reliable in quality and has more obvious advantages for product yield improvement, cost reduction, industrialization realization and better clinical application.

The medicine for preventing and controlling diarrhea of livestock and poultry is prepared with medicinal charcoal, fried kaoliang, sodium humate and talc in certain weight proportion, and through crushing, grinding and mixing. Before application, the medicine in 1-2 wt% is mixed into feed for animal to take. At the same time, water with sugar and salt is added for replenishing body fluid and raising curative effect. The medicine has high curative rate, no adverse reaction, no medicine residue, no drug resistance and other advantages, and is suitable for various kinds of livestock and poultry.

A preparation method for high-purity pomalidomide comprises the following steps: (1) adding 3-nitro-N-(2,6-dioxo-3-piperidyl)phthalimide, palladium carbon and N-methyl pyrrolidone to a reaction kettle, vacuumizing, then introducing hydrogen gas, carrying out suction filtration after a reaction is complete, adding medicinal charcoal to the filtrate, stirring, heating, and carrying out suction filtration; and (2) adding an alkaline aqueous solution to the filtrate finally obtained in the step (1), stirring, then adding purified water, cooling and crystallizing, carrying out suction filtration, adding purified water to the obtained filter cake, stirring, carrying out suction filtration, washing, and drying to obtain the high-purity pomalidomide product. The preparation method provided by the invention has the advantages of simple operation and mature and stable technology, and can significantly improve the quality of pomalidomide; the purity of the obtained product is greater than 99.5%, the contents of single impurities are all less than 0.1%, and the medicinal requirements are met.