5results about How to "Substance reduction" patented technology

The invention discloses an application of a Piezo1 inhibitor in preparation of a medicine for treating necrotizing enterocolitis. The Piezo1 inhibitor can be applied in preparation of the medicine for treating the necrotizing enterocolitis. The Piezo1 inhibitor can also be applied to preparation of drugs for relieving NEC intestinal epithelial barrier injury. The Piezo1 inhibitor can also be applied to preparation of drugs for reducing calcium influx in intestinal epithelial cells and calcium / calmodulin dependent protein kinase activity. The application has the beneficial effects that the effect and mechanism of the Piezo1 for regulating and controlling the calcium ion influx and promoting the NEC severity degree by the calcium / calmodulin dependent protein kinase activity level are discussed for the first time from multiple aspects of animals, tissues, cells, molecules and the like, and the effect and mechanism of the activated intestinal epithelial cell Piezo1 in NEC inflammatory injury and barrier repair are clarified for the first time; the knockout of the gene can improve the NEC severity of mice, and a new intervention target is provided for clinical treatment.

This utility model discloses a secondary battery and an electrical device, belonging to the field of battery technology. The secondary battery includes a wound cell, which includes a flat region and a corner region. The wound cell includes a positive electrode, a negative electrode, and a separator between the positive and negative electrode. The positive electrode includes a positive current collector and a flame-retardant layer and a positive active material layer sequentially disposed on at least one surface of the positive current collector. This utility model controls the thickness relationship between the flame-retardant layer and the positive active material layer in the flat region and the corner region, thereby significantly improving the lithium plating phenomenon at the corner.

The invention belongs to the technical field of mixing plant main machine cleaning methods, and particularly relates to a cleaning method for a mixing plant discharge hopper. The method is characterized by comprising the steps of 1, storing air in an air storage tank, starting an air compressor to inflate the air storage tank, 2, injecting water into an air pressure water tank, closing an air pressure water tank air supply pneumatic ball valve during water injection, closing an air pressure water tank drainage pneumatic ball valve, opening an air pressure water tank exhaust pneumatic ball valve, and exhausting air pressure in the air pressure water tank. 3, cleaning is conducted, specifically, an air pressure water tank drainage pneumatic ball valve and a cleaning airflow supply pneumatic ball valve are opened at the same time when cleaning is conducted, mixed airflow of airflow and clean water passes through an air pipe and a cleaning spray head, and the air pressure in the air pressure water tank is discharged; the cement is sprayed to the position, where the cement remains, of the inner side of the discharging hopper, the cement is cleaned away, and the discharging hopper does not cake after being cleaned up every time. The impact force of gas and the cleaning force of water are mixed together, and the effect that concrete residues in the discharge hopper at the bottom of the main machine of the mixing plant can be automatically cleaned without much water can be achieved.

The utility model discloses a filter bag cleaning and recycling device, including high pressure cleaning module, reagent infiltration module, flexible cleaning module, drying module and filter material decomposition module, high pressure cleaning module is used for washing the dirt on filter bag, reagent infiltration module is used for infiltrating filter bag, flexible cleaning module is used for cleaning the filter bag after infiltration, drying module is used for drying filter bag, and filter material decomposition module is used for crushing the filter bag after drying. Therefore, the utility model can clean and recycle filter bag, improve the utilization of materials, reduce the cost, and is more environmental protection.

The utility model belongs to the technical field of quantitative filling equipment, and particularly relates to enzyme stock solution sterile quantitative filling equipment which comprises a liquid storage tank. One side of the liquid storage tank is communicated with a quantitative cylinder through a liquid conveying pipe; a quantifying plate is slidably connected into the quantifying cylinder; a screw rod is rotationally connected to the center of the quantifying plate, and the other end of the screw rod penetrates through the quantifying cylinder in a threaded manner; the bottom end of the quantifying cylinder is communicated with a first liquid discharge pipe; when the filling amount needs to be changed, the screw rod only needs to be rotated forwards and backwards, the quantitative plate can be driven to ascend and descend in the quantitative cylinder, filling quantitative adjustment is carried out, the effect of rapidly changing the filling amount is achieved, flexibility is improved, after adjustment is completed, the solenoid valve of the liquid conveying pipe is opened, and the solenoid valve of the first liquid discharging pipe is closed and started till the quantitative cylinder is filled with the enzyme stock solution. According to the method, fewer devices are adopted, so that the quantitative cost is reduced, and the method is suitable for being put into use by initially created enterprises or enterprises with limited budget.