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Colored medicinal charcoal film coated tablet preparation method

A technology of film-coated tablets and medicinal charcoal, which is applied in the direction of anti-toxic agents, sugar-coated pills, pill delivery, etc. It can solve the problems of medicinal charcoal tablets’ appearance and taste, which are difficult for patients to accept, and there are no film-coated tablets.

Active Publication Date: 2008-01-16
河北长天药业有限公司
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AI Technical Summary

Problems solved by technology

[0004] However, the medicinal charcoal tablets issued by the Ministry of Health do not have colored film-coated tablets. In the use of clinical patients, the black appearance and taste of medicinal charcoal tablets are still unacceptable to patients.

Method used

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Examples

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Effect test

example 1

[0008] 1. Example one: medical charcoal and pharmaceutical adjuvant weight percentage are combined to make colored film-coated tablet.

[0009] Medicinal Charcoal 67%

[0010] Starch 10%

[0011] Sucrose 5%

[0012] Hypromellose 3%

[0013] Tablet binder 10%

[0014] Magnesium Stearate 2%

[0015] Colored coating powder 2.5%

[0016] 80% ethanol 20ml

[0017] Makes 100 pieces

[0018] 2. Preparation steps:

[0019] ①. Take medicinal charcoal, mix with starch, white sugar, and hydroxypropyl cellulose, add tablet binder and mix evenly, pass through a 14-mesh sieve to make wet granules, and dry the granules at 50-60°C until they contain 25% water. Sieve through a 16-mesh sieve, mix with magnesium stearate, press into a tablet machine, and dry at 80°C to obtain medicinal charcoal tablets.

[0020] ②Dissolve the coating powder in ethanol and stir to dissolve.

[0021] ③. In the coating pan, the tablet prepared in ① is coated with the solution prepared in ② to obtain the c...

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Abstract

The invention discloses a preparation method of painted medicinal carbon film-coating tablet produced by the raw material of medicinal carbon and medicinal excipients. The invention is characterized in that painted medicinal carbon film coating tablets are produced in the preparation method, thus the visual defect of black medicinal carbon is overcome and the painted tablets are easy to be accepted by patients. The smooth and round form of the painted medicinal carbon film coating tablet can help effectively guarantee the tablet quality and improve the clinical compliance of patients.

Description

technical field [0001] The invention relates to a method for preparing colored film-coated tablets of Chinese medicinal charcoal tablets in "Drug Standards of the Ministry of Health of the People's Republic of China" (the first volume of chemical medicine), especially to completely cover the black appearance of medicinal charcoal tablets, so that patients can easily accept them Preparation of colored film-coated tablets for improved clinical compliance. technical background [0002] "Drug Standards of the Ministry of Health of the People's Republic of China" (the first volume of chemical medicine) has clinically applied medicinal charcoal tablets for adsorbing drugs. [0003] Medicinal charcoal is a porous carbon-containing substance made of organic substances after high-temperature carbonization, activation, pickling, and water washing to remove impurities, and drying and crushing. Its developed pore structure and huge specific surface area (1000-1400m 2 / g), has a strong...

Claims

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Application Information

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IPC IPC(8): A61K33/44A61K9/28A61P39/02A61P1/12A61P1/00
Inventor 施金锋张瑞范建立闫亮
Owner 河北长天药业有限公司
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