A traditional Chinese medicine composition for treating acute alcoholic liver injury and its preparation method

A technology of alcoholic liver injury and composition, which is applied in the field of traditional Chinese medicine composition and its preparation with the effect of treating acute alcoholic liver injury, and can solve many problems such as homology of medicine and food, achieve obvious effects, and improve the effect of pathological manifestations

Active Publication Date: 2020-04-03
CHINA ACAD OF SCI NORTHWEST HIGHLAND BIOLOGY INST
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

For drinkers, the fundamental measure to improve their physical condition is to quit alcohol, but alcohol addiction makes it difficult for most drinkers to completely quit alcohol, so while drinking in moderation, there is an urgent need for traditional Chinese medicine with liver protection function Composition to prevent liver damage from alcohol
At present, dozens of traditional Chinese medicines have been reported to have anti-liver damage, such as rhubarb, cordyceps, astragalus, salvia miltiorrhiza, medlar, schisandra, etc. Among them, there are many Chinese and Tibetan medicinal materials with the same origin

Method used

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  • A traditional Chinese medicine composition for treating acute alcoholic liver injury and its preparation method

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Experimental program
Comparison scheme
Effect test

Embodiment 1

[0023] Take 12g of Qinglan heterophylla, 5g of saxifrage tangut, 5g of Kangding sage, 10g of Gentiana japonica, and 10g of chanterelle, add water to decoct 3 times for 20 minutes each time, and combine the decoctions to obtain a decoction.

Embodiment 2

[0025] Chrysanthemum heterophyllum 16g, saxifrage tangutate 8g, sage sage Kangding 3g, Gentiana twig 8g, chanterelle 12g, reflux extraction with 60-80% v / v ethanol for 3 times, each time for 30 minutes, and the alcohol extraction solution for later use; dregs Add water and decoct twice, each time for 20 minutes, combine the decoction, recover ethanol from the alcohol extract, combine with the decoction, concentrate, add appropriate amount of auxiliary materials to prepare granules.

Embodiment 3

[0027] 15g of Qinglan different leaves, 6g of saxifrage tangut, 4g of Kangding sage, 9g of Gentiana japonica, 11g of chanterelles, add water and soak 3 times at 80 degrees Celsius for 2 hours each time, combine the extracts, after concentration, add appropriate amount of ethanol After the precipitation is complete, take the precipitate and dry it for later use. After the supernatant is concentrated, add an appropriate amount of microcrystalline cellulose to spray dry, and then mix the dried product with the precipitate and pack it into a capsule to obtain a capsule.

[0028] Beneficial effects of the present invention are specifically illustrated below by test examples

[0029] 1. Experimental materials

[0030] 1.1 Experimental drugs were set in different dose ratio groups, which were respectively ratio group 1 (Chrysanthemum heterophyllum: Saxifraga tangutica: Sage kangding: Gentiana japonica: Yellow mushroom = 2.4:1:1:2:2, namely different Ye Qinglan 12g, Tangut saxifrage ...

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Abstract

The invention discloses a traditional Chinese medicine composition for treating acute alcoholic liver damage.The traditional Chinese medicine composition is prepared from herba dracocephali heterophylli, saxifraga tangutica Engl., salvia prattii Hemsl., radix gentianae macrophyllae and sporocarp of pulveroboletus ravenelii (Berk.et Curt.) Murr..The invention further discloses a preparation method of the traditional Chinese medicine composition.According to the traditional Chinese medicine composition, five traditional Chinese medicines of herba dracocephali heterophylli and the like are combined for use, the synergetic effects are achieved, the effect on treating the acute alcoholic liver damage is obvious, pathological manifestations of liver damage, specially the acute alcoholic liver damage can be significantly improved, and a new choice is provided for clinical medication.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicine, and in particular relates to a traditional Chinese medicine composition capable of treating acute alcoholic liver injury and a preparation method thereof. Background technique [0002] In recent years, with the improvement of our living standard and the change of diet structure, the consumption of alcohol is increasing day by day, and the incidence of alcoholic liver injury in our country is increasing year by year. Alcoholic liver injury has become the second major liver disease after viral hepatitis. Alcoholic liver injury is a progressive disease that can cause liver dysfunction such as hepatic cell necrosis, hepatic steatosis, and cirrhosis to varying degrees. In the later stage, it will seriously endanger the health of the body and may eventually lead to the occurrence of liver cancer. Alcoholic liver injury has the characteristics of general susceptibility and short in...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/537A61P1/16A23L33/10
CPCA23V2002/00A61K9/0095A61K9/4866A61K36/06A61K36/185A61K36/51A61K36/53A61K36/537A61K2236/33A61K2236/331A61K2300/00A23V2200/30A23V2200/334
Inventor 王启兰党军陶燕铎张莉王蒲
Owner CHINA ACAD OF SCI NORTHWEST HIGHLAND BIOLOGY INST
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