53 results about "Dracocephalum heterophyllum" patented technology

The invention provides a lipid-lowering and pressure-releasing folium ginkgo health-care product. The health-care product comprises the following raw materials in part by weight: 50-100 parts of folium ginkgo, 10-20 parts of fructus rubi, 10-20 parts of rehmannia glutinosa, 10-20 parts of Chinese angelica, 10-20 parts of dogwood, 10-20 parts of radix salviae miltiorrhizae, 10-20 parts of poria cocos, 10-20 parts of dracocephalum heterophyllum benth, 10-20 parts of codonopsis pilosula, 10-20 parts of herba eupatorii, 10-20 parts of gynostemma pentaphylla, 10-20 parts of astragalus mongholicus, 10-20 parts of rhizoma alismatis, 10-20 parts of safflower carthamus, 10-20 parts of scutellaria baicalensis, 10-20 parts of radix paeoniae alba, 10-20 parts of gardenia, 10-20 parts of white atractylodes rhizome, 10-20 parts of glossy privet fruit, 10-20 parts of tartary buckwheat and 10-20 parts of propolis. According to the invention, as the folium ginkgo is extracted, the active ingredients of the folium ginkgo are retained, and the toxicity is reduced; and as the traditional Chinese medicinal materials, which can activate blood and remove stasis and can obviously reduce the blood sugar and fat serum triglyceride, are added, the microcirculation can be improved, the immunity is enhanced, and people can accept easily, as a result, the lipid-lowering and pressure-releasing efficacy can be better achieved. According to the invention, the health-care product cannot be taken by pregnant women and young children.

The invention relates herba dracocephalum heterophylli volatile oil possessing the bacteriostatic and germicidal action and its application. The method adopts steam distillation to extract the herba dracocephalum heterophylli volatile oil and adopts gas-chromatography/mass spectra to analysis the volatile oil, identifying the 83 components and 89.83% total content. The volatile oil can kill and suppress the staphylococcus, streptococcus, gonococcus, enterobacter, Escherichia, salmonella, shigella, pseudomonas, bacillus, oidiomycin, cryptococcus, aspergillus, penicillium, mucor, epidermophytin, micromonospora, trichophyton and other bacteriums. The herba dracocephalum heterophylli volatile oil is used for foodstuffs, drugs, health products, cosmetic products and other industries.

The invention relates to a preparation method and an application of dracocephalum heterophyllum benth fractionated extracts. Compared with the existing anti-virus synthetic medicines, the dracocephalum heterophyllum benth fractionated extracts have low toxicity, are safe and reliable and have strong pharmaceutical effect; and the dracocephalum heterophyllum benth raw materials are abundant and cheap, the extraction process is simple and the preparation cost is low, so the dracocephalum heterophyllum benth fractionated extracts can be prepared into various dosage forms.

The invention relates to a preparation method and an application of an effective part of dracocephalum heterophyllum benth. The method comprises the steps that an aboveground part of the dracocephalum heterophyllum benth is smashed, extracted by an organic solvent, namely alcohol, and subjected to macroporous resin separation and purification to form the effective part of the dracocephalum heterophyllum benth. A preliminary activity screening test proves that the effective part of the dracocephalum heterophyllum benth obtained by the method has functions of lowering renal hypertension and rat blood pressure, and enhancing diastole and systole, and can also effectively prevent and treat hypertension complications including myocardial hypertrophy, renal injuries and vascular endothelial injuries. The method is simple in technology, low in production cost, and easy to control, and does not require high temperature or high pressure equipment, and the quality of the effective component is stable.

This invention relates essential oil constituents citronellol and rose oxides and other constituents from a cold desert plant i.e. Dracocephalum heterophyllum benth, the present invention also provides a process for the extraction of the essential oil.

The invention relates to a method for separating and preparing ursolic acid methyl ester from dracocephalum heterophyllum benth. The method comprises steps as follows: (1), dracocephalum heterophyllum benth is cut into sections and subjected to reflux extraction by ethyl alcohol to obtain an extracting solution; and the extracting solution is concentrated under reduced pressure to obtain extracts; (2), the extracts are extracted by ethyl acetate under the ambient temperature condition to obtain an extract liquid, and the extract liquid is concentrated under reduced pressure to obtain crude extracts of ursolic acid methyl ester; (3), the crude extracts of ursolic acid methyl ester are dissolved in ethyl acetate, silica gel is added, the mixture is stirred and mixed, silica gel columns are fed with a dry method twice after the solvent of ethyl acetate volatilizes, and purer ursolic acid methyl ester is obtained after concentration under reduced pressure; and (4), the purer ursolic acid methyl ester is dissolved and crystallized for impurity removal and then filtered to obtain ursolic acid methyl ester crystals. The method is simple, simple and convenient to operate and high in separation efficiency and separation purity; and meanwhile, the ursolic acid methyl ester crystals obtained with the method can be applied to treatment of tumor and acute liver injury diseases.

The invention belongs to the technical field of daily chemical washing products, and particularly relates to a bacteriostatic agent composition, a preparation method thereof and an application of thebacteriostatic agent composition in antibacterial laundry detergents. The bacteriostatic agent comprises long-chain alkyl betaine@graphene quantum dots and a natural plant extract, wherein the mass ratio of the long-chain alkyl betaine@graphene quantum dots to the natural plant extract is 1:8-1:1, wherein the natural plant essential oil is a mixture of two or more selected from ammi visnaga essential oil, tree peony root bark essential oil and dracocephalum heterophyllum essential oil. After the plurality of kinds of natural antibacterial plant essential oil are effectively compounded, the compounded natural antibacterial plant essential oil is compounded with a small amount of graphene quantum dot (GQDs) nano antibacterial material to prepare the green, efficient and environment-friendlybacteriostatic agent composition, and the bacteriostatic agent composition is applied to antibacterial laundry detergents.

The invention discloses a traditional Chinese medicine composition for treating tympanites caused by qi stagnation and damp obstruction. The composition is composed of the following traditional Chinese herbals in parts by weight: 20 to 30 parts of embelia longifolia, 30 to 40 parts of lysimachia hemsleyana, 6 to 8 parts of thyme, 10 to 15 parts of dracocephalum heterophyllum, 8 to 12 parts of abutilon peniculatum, 10 to 15 parts of lathyrus davidii, 30 to 35 parts of fruit of common pratia, 8 to 10 parts of stephania excentrica, 8 to 12 parts of fruticulos moghania, 18 to 25 parts of trema cannabina, 18 to 25 parts of dayflower, 6 to 10 parts of peliosanthes minor, 18 to 25 parts of day lily, 25 to 30 parts of parnassia wightiana, and 18 to 25 parts of fragrant ainsliaea. The provided traditional Chinese medicine composition can effectively treat tympanites caused by qi stagnation and damp obstruction. The results of applications on patients in many years show that the effective rate can reach 100%, the curative effect is good, and no relapse happens after the curing.

The invention discloses a traditional Chinese medicine preparation for treating hyperthyroidism. The traditional Chinese medicine preparation disclosed by the invention is prepared from the following medicinal materials in weight: 10 g of felwort, 10 g of cortex phellodendri, 10 g of raw arisaema consanguineum schott, 25 g of selfheal, 25 g of air potato, 25 g of yellow myrobalan peel, 5 g of semen sojae germinatum, 15 g of Lobaria retigera, 15 g of oriental blechnum frond, 15 g of rhizoma anemarrhenae, 8 g of radix bupleuri, 20 g of halogen alkaline, 8 g of dracocephalum heterophyllum, and 5 g of pig's thyroid gland. Found from clinical experiments, the obvious effect of effectively treating hyperthyroidism is achieved by selecting proper medicinal materials and a mixture ratio thereof; and furthermore, the traditional Chinese medicine preparation disclosed by the invention is safe and free from toxic and side effect.

The invention relates to a preparation method and application of dracocephalum heterophyllum benth volatile oil. Compared with existing antiviral synthetic drugs, the dracocephalum heterophyllum benth volatile oil has low toxicity and strong drug action and is safe and reliable. Moreover, the dracocephalum heterophyllum benth raw material is rich and cheap, is simple in extraction process and low in preparation cost and can be prepared into various dosage forms.

The invention relates to a method for preparing total polyphenol of dracocephalum heterophyllum benth. The method comprises the following steps: (1) extracting, namely performing alcohol extraction and decompression concentration on dracocephalum heterophyllum benth herbal powder to obtain a dracocephalum heterophyllum benth alcohol extract; (2) removing pigment, namely dissolving the dracocephalum heterophyllum benth alcohol extract, and extracting the dracocephalum heterophyllum benth alcohol extract to obtain a water extract; (3) crudely preparing, namely performing extraction and decompression concentration on the water extract to obtain a dracocephalum heterophyllum benth crude product; and (4) finely preparing, namely dissolving the dracocephalum heterophyllum benth crude product into a suspension, regulating the pH value of the suspension to be 3-4 with a HCl solution of 0.5mol/L, eluting the solution with a processed macroporous resin chromatography column by adopting a wet method, and collecting 50-70% alcohol water eluent; and performing decompression concentration on the 50-70% alcohol water eluent to obtain a finished product of the total polyphenol of dracocephalum heterophyllum benth.

The invention relates to dracocephalum heterophyllum granules and a preparation method thereof. The dracocephalum heterophyllum granules are prepared from the following raw materials in parts by weight: 5-25 parts of dracocephalum heterophyllum, 10-30 parts of inulin, 15-45 parts of dextrin, 1-10 parts of carboxymethyl cellulose and 5-35 parts of sucrose. The dracocephalum heterophyllum granules have the effects of clearing liver heat and protecting liver.

The invention discloses a Chinese medicinal composition for treating lymphnoditis, which is mainly prepared from the following raw material medicines in parts by mass: 9 to 13 parts of phellodendron, 10 to 14 parts of portulaca oleracea, 11 to 14 pars of andrographis paniculata, 10 to 15 parts of gentian, 6 to 10 parts of oyster, 8 to 14 parts of ampelopsis japonica, 11 to 16 parts of houttuynia cordata, 9 to 14 parts of myrrh, 12 to 16 parts of iris confuse, 6 to 10 parts of Indian stringbush root, 12 to 17 parts of platycodon grandiflorus, 8 to 15 parts of thesium chinense turcz, 13 to 16 parts of dracocephalum heterophyllum and 7 to 14 parts of pterolobium punctatum. The Chinese medicinal composition is prepared by years of clinical practice summary, has effects of clearing heat and removing toxicity and relieving swelling and pain and has an outstanding curative effect.

The invention discloses a traditional Chinese medicine preparation for treating hepatobiliary lithiasis and a preparation method thereof. The traditional Chinese medicine preparation is prepared from the following medicinal materials in parts by weight: 30-48 parts of capillary wormwood herb, 22-37 parts of longhairy antenoron herb, 13-26 parts of szechuan lovage rhizome, 9-18 parts of Chinese angelica, 5-12 parts of Indian iphigenia bulb, 3-11 parts of liquoric root, 5-16 parts of rhizoma corydalis, 3-9 parts of cape jasmine fruit, 1-7 parts of baical skullcap root, 2-8 parts of Chinese thorowax root, 3-8 parts of dracocephalum heterophyllum, 1-7 parts of nakedflower beautyberry branchlet and leaf and 3-6 parts of dried lily bulb. The traditional Chinese medicine preparation disclosed by the invention is reasonable in formula and convenient and safe to take, does not have toxic or side effects, and is accurate and significant in clinically-verified curative effect. Years of clinical observation shows that the traditional Chinese medicine preparation has the functions of nourishing yin and softening the liver, nourishing yin and removing fire, and diminishing inflammation, tonifying gallbladder and removing stones, and has the effective rate of more than 90% in treating liver-yin deficiency and gallstones and intrahepatic duct stones caused by interior damp-heat.

The invention relates to a method for isolating and preparing rosmarinic acid from Dracocephalum heterophyllum, comprising the steps of (1) extracting, to be specific, soaking powder of Dracocephalum heterophyllum herb, and performing reflux extraction and vacuum concentration to obtain Dracocephalum heterophyllum extract; (2) cleaning by microporous resin, to be specific, dissolving the Dracocephalum heterophyllum extract, filtering, feeding to MCI microporous resin columns, eluting, collecting 50% ethanol solution eluent, and subjecting the 50% ethanol solution eluent to vacuum concentration to obtain rosmarinic acid crude extract; (3) isolating and purifying by hydrophilic liquid chromatography, to be specific, dissolving the rosmarinic acid crude extract, filtering with a microporous filter membrane, and isolating and purifying by using hydrophilic liquid chromatography to obtain rosmarinic acid having purity of higher than 98%. In addition, the invention also discloses application of the rosmarinic acid. The method is simple and is easy for large-scale production.

The invention discloses a traditional Chinese medicine composition for treating liver-yang hyperactivity hypertension and a preparation method for the traditional Chinese medicine composition. The traditional Chinese medicine composition is characterized by being prepared from the following medicinal materials in parts by weight: 6-9 parts of dracocephalum heterophyllum benth, 10-15 parts of harlequin glorybower leaves, 20-25 parts of salsola ruthenica, 6-9 parts of uncaria lancifolia, 25-30 parts of desmodium laxiflorum, 6-9 parts of earthworms, 12-15 parts of froggrass, 20-25 parts of themeda triandra seedlings, 6-9 parts of piptanthus concolor, 12-15 parts of eastern bracken fern rhizome, 6-10 parts of apocynum venetum, 40-50 parts of armillaria ostoyae, 12-15 parts of seeds of feather cockscomb, 9-12 parts of cladonia alpestris, 6-9 parts of alpine swertia and 6-9 parts of rhizome of whorledleaf solomonseal. The traditional Chinese medicine composition can effectively treat the liver-yang hyperactivity hypertension, and has an effective rate up to 96.6% according to the multi-year use of a plurality of patients.

The invention discloses an external application patch for treating lymphnoditis. The external application patch is mainly prepared from the following raw materials in parts by weight: 12-17 parts of fructus forsythiae, 9-12 parts of carpesium divaricatum, 6-9 parts of Indian stringbush roots, 10-15 parts of thesium chinense, 7-15 parts of heritiera parvifolia, 10-16 parts of rust-brown crotalaria, 11-17 parts of iris confuse, 9-18 parts of houttuynia cordata, 12-16 parts of erigeron annuus, 13-18 parts of dracocephalum heterophyllum benth, 10-17 parts of trichosanthes kirilowii maxim, 9-14 parts of radix gentianae and 11-16 parts of golden cypress. Being prepared according to the traditional Chinese medicine principles, the external application patch has the effects of clearing away heat, relieving pain, subsiding swelling and removing stasis, can be used for effectively treating acute and chronic lymphnoditis and is more secure in treatment; through clinical verification, the prepared product is rapid in effect and effective in treatment.

The invention discloses a medicine for treating liver meridian damp-heat type infantile enuresis and a preparation method thereof, wherein, the medicine is prepared from the following raw herbal materials: rauwolfia, sheepear inula herb, rubia cordifolia, fortune firethorn fruit, campsis grandiflora, calamitas urinae hominis, dracocephalum heterophyllum, creeping oxalis, malvastrum coromandelianum, narrow-leaved lindernia, goat-ear elecampane root, aralis root, climbing fig, herb of wight parnassia, mallotus apelta, physalis angulata, blumea, angled bittersweet root, trifoliate acanthopanax root or root-bark, prepared rehmannia root, fructus lycii, chrysanthemum, herba ecliptae, ganoderma lucidum, lotus seed, pimpinella thellungiana, eastern bracken fern rhizome, fructus aurantii, cynanchum wilfordii and seedling of mapleleaf excoecaria. The medicine for treating the liver meridian damp-heat type infantile enuresis has the beneficial effects of purging the liver of pathogenic fire and clearing damp, clearing away heat and toxic materials, nourishing kidney yin, and benefiting qi for tranquillization; according to the medicine provided by the invention, the theory of traditional Chinese medicine is utilized; treatment based on syndrome differentiation is performed; the pertinence is higher; the curative effect is significant; each herbal material contains a variety of pharmacological ingredients, and has a wide range of indication; the toxic and side effects are low, and the curative effect is significant.

The invention provides a traditional Chinese medicine for treating viral hepatitis B. The traditional Chinese medicine is prepared from the following raw materials: aconitum tanguticum, lagotis brevituba maxim, dracocephalum heterophyllum benth, polygonum cuspidatum, dandelion, radix sophorae flavescentis, herba epimedii, radix curcumae, peach kernels, dried ginger, turtle shells, dendrobe, salviae miltiorrhizae, hairyvein agrimony, rhizoma polygonati, fructus amomi, Chinese herbaceous peony, liquorice, herba lycopi, bupleuri radix, carthami flos, bletilla striata, lignum aquilariae resinatum,radix et rhizoma rhei, cortex phellodendri and cortex moutan. According to the traditional Chinese medicine, through reasonable compatibility of the raw materials, the special performance and effectsof the raw materials are brought into full play, meanwhile, the complementary effect of the raw materials is considered, the medicine effects supplement one another, and the hepatitis B treatment effect is remarkable.

The invention discloses a traditional Chinese medicine composition for treating proctitis. The traditional Chinese medicine composition is prepared from the following main raw materials in parts by weight: 8 to 11 parts of radix paeoniae alba, 3 to 8 parts of ephedra (added later), 9 to 21 parts of poria cocos, 8 to 14 parts of selfheal, 13 to 15 parts of divaricate saposhnikovia root, 11 to 15 parts of szechwan chinaberry fruit, 9 to 16 parts of auricled hedyotis herb, 4 to 10 parts of myrobalan, 12 to 20 parts of hypericum japonicum, 10 to 16 parts of angelica sinensis, 14 to 19 parts of pseudo-ginseng, 6 to 14 parts of dracocephalum heterophyllum benth, 4 to 8 parts of concha haliotidis, 5 to 8 parts of streptocaulon griffithii hook, and 9 to 17 parts of schisandra chinensis. The traditional Chinese medicine composition is a pure traditional Chinese medicine preparation and free of obvious toxic and side effects; the composition achieves selection of treatment based on the differential diagnosis according to the principle of traditional Chinese medicine; the traditional Chinese medicine composition has a plurality of functions such as clearing away heat and relieving exterior syndrome, relieving swelling and pain, and clearing dampness and promoting diuresis; and the clinic application shows that the product is obvious in treatment effect, safe and reliable.

The invention discloses an endothelium corneum gigeriae galli membrane spraying agent for treating dental ulcer. In order to eliminate the deficiencies of a dental ulcer membrane in the prior art, theendothelium corneum gigeriae galli membrane spraying agent is subjected to compatibility with endothelium corneum gigeriae galli, Plantago erosa Wall herb, oyster rhoeo flower, serrate holly leaf, dracocephalum heterophyllum benth, hawthorn branchlet leaf, carallia brachiate fruit, semen hygrophilae, dunn antiotrema root, cortex berberis heteropodae, herba chenopodii ambrosioides, cuttlebone, champion dutchmanspipe root, chitosan oligosaccharide and polyvinylpyrrolidone to perform an effects on obviously inhibiting bacteria, diminishing inflammation and alleviating pain. The spared medicine liquid can quickly form a membrane so as to be favorable for effective ingredients to be dipped into an affected part to generate physical reaction, the effective ingredients are unlikely to lose, a better treatment effect is generated, meanwhile, no hormone medicines are added, and the endothelium corneum gigeriae galli membrane spraying agent has the advantage of high safety.

The invention provides application of dracocephalum heterophyllum benth in medicines for prevention and treatment of joint damage/rheumatoid arthritis. The dracocephalum heterophyllum benth dracocephalum heterophyllum benth is used as a medicine for prevention and treatment of rheumatoid arthritis. The dracocephalum heterophyllum benth significantly down-regulates the levels of proinflammatory cytokines TNF-alpha, IL-6 and IL-1beta in important inflammatory sites such as spleen and paw by inhibiting joint damage and swelling; at the same time, the dracocephalum heterophyllum benth lowers the serum levels of cytokines TNF-Alpha or / and IL-6 to relieve arthritis/joint injury in mice and prevent and treat rheumatoid arthritis. The dracocephalum heterophyllum benth has significant therapeuticeffects on joint damage/rheumatoid arthritis caused by autoimmune immune response of the body and has small side effects and remarkable therapeutic effects, the material distribution is wide, resources are abundant, and preparation in batches is easy.

The invention provides a traditional Chinese medicine preparation for treating neurasthenia and belongs to the technical field of traditional Chinese medicines. Raw active components are prepared mainly by using bitter tea leaf, Dracocephalum heterophyllum, Mimosa pudica, Crepis turczaninowii, Cratoneuron filicinum, lotus seed, jasminum grandiflorum, Ficus esquiroliana, Grifola frondosa, Berchemia floribunda, mulberry fruit, Polytrichum commune, Cyperus Michelianus and Artocarpus hypargyreus root through extraction in water and extraction in ethanol with volume concentration of 70 to 80 percent, then pharmaceutically acceptable carriers are added, and finally the traditional Chinese medicine preparation is prepared according to a conventional method for preparing traditional Chinese medicine preparations. The traditional Chinese medicine preparation provided by the invention is prepared by carefully selecting raw medicinal materials and proportions according to the pathogenesis of neurasthenia, effective components interact with one another, have a synergetic effect and jointly achieve the efficacies of clearing liver, purging fire, nourishing heart, smoothing nerves, soothing liver, relieving depression, nourishing spleen and kidney, nourishing yin, clearing heat, reinforcing qi, nourishing blood, promoting blood circulation, dredging collaterals, benefiting intelligence and strengthening brain, the traditional Chinese medicine preparation has a remarkable curative effect of treating neurasthenia, the effect is achieved quickly, the treatment course is short, the cure rate is high and the treatment is thorough; and the medicine properties are gentle, the safety and reliability are high, no dependence is caused and no toxic and side effects exist.