38 results about "Stephania epigaea" patented technology

The invention belongs to the technical field of pharmacy, and particularly discloses a stephania hainanensis total alkaloid extract extracted from stephania hainanensis tubers and a preparation method thereof. The preparation process is as follows: material (stephania hainanensis dry tubers); grinding; soaking in a moderate amount of 0.01 to 10 percent of hydrochloric acid or sulfuric acid; 1 to 4 times of ultrasonic extraction; filtration; storng-acid cation exchange resin purification; solvent recovery for drying; and stephania hainanensis total alkaloid extract. The extract mainly comprises L-tetrahydropalmatine, palmatine, fangchinoline, hanfangchin and other active ingredients, the percentage by weight of stephania hainanensis total alkaloid is greater than or equal to 70 percent, the percentage by weight of the palmatine is greater than or equal to 20 percent, and the percentage by weight of the fangchinoline is greater than or equal to 40 percent. Reports on the stephania hainanensis total alkaloid extraction process are not found in related literatures so far, the operation flow of the method is simple, the purity of the product is high, the efficacy is remarkable, and the method disclosed by the invention is applicable to industrial production and the exploitation and utilization of local stephania hainanensis resources.

The invention provides a quick antiphlogistic and analgesic Chinese herbal preparation, which is prepared from the alcohol extract of the following raw material medicaments in part by weight: honeysuckle flower 0.5-2, pseudo-ginseng 0.5-2, Stephania epigaea 0.5-2, Indian iphigenia bulb 0.5-2, Bixuelin 0.5-2, thunder god vine 0.5-2, common dysosmatis rhizome and root 0.5-2, dandelion 0.5-2, eucommia bark 0.5-2, costustoot 0.5-2, manyflower solomonseal rhizome 0.5-2, Yunnan manyleaf paris rhizome 0.5-2, tall gastrodia tuber 0.5-2, Chinese magnoliavine fruit 0.5-2, wolfberry fruit 0.5-2, plant soot 0.5-2, and one or more of Chinese alangium root 0.5-1, wild Indian buead 0.5-1, obscured homalomena rhizome 0.5-1, rhizoma corydalis 0.5-1, medicinal cyathula root 0.5-1, changium smyrnioide 0.5-1, tuber fleece flower root 0.5-1, clematis root 0.5-1, drynaria rhizome 0.5-1, cortex acanthopanacis 0.5-1, radix asparagi 0.5-1, phytolacca esculenta van houtte 0.5-1, barbed skullcap herb 0.5-1, garden balsam stem 0.5-1, chinese arborvitae twig 0.5-1, Haijinhe 0.5-1, spreading hedyotis herb 0.5-1, lalang grass rhizome 0.5-1, galium aparine L. 0.5-1 and common clubmoss herb 0.5-1. The extract is auburnish black or light black, great bitter and light spicy. The preparation has a remarkable treatment effect on tooth pain and acute gastroenteritis. After 10 milliliters of the preparation can be kept in mouth for 10 minutes and swallowed, pains are relieved. And when the preparation is taken by three times for one day, the pains are removed. Acute gastroenteritis, appendicitis and renal colic can be cured within 1 to 3 days by the preparation. The preparation has certain treatment effect on arthritis, traumatic injuries, burns and other injuries.

The invention discloses a stephania epigaea tissue culture reproduction method. The stephania epigaea tissue culture reproduction method comprises the following steps: (1) explant selection, (2) explant sterilization, (3) cluster bud induction, (4) multiplication culture, (5) rooting culture and the like. A stephania epigaea tissue culture rapid propagation system is established successfully, andstephania epigaea cluster bud induction rate, multiplication factors and the rooting rate are improved remarkably. The stephania epigaea tissue culture reproduction method has the advantages of high tissue culture efficiency and low cost, and the problems that wild stephania epigaea resources are developed excessively, medicinal material supply is less, a planting scale is limited by the number and quality of seedlings and the like are solved.

The invention relates to a decoction for treating nausea and vomiting caused by anesthesia, which is prepared from the materials in part by weight as follows: 5-10 parts of cowherb seed, 5-15 parts of wikstroemia indica, 1-5 parts of subprostrate sophora, 3-8 parts of herba kalimeridis, 1-10 parts of exocarpium, 1-10 parts of rhizoma typhonii, 5-10 parts of stephania epigaea, 3-8 parts of crotalaria sessiliflora, 5-10 parts of daphne genkwa, 10-20 parts of short-pedicel aconite root, 20-30 parts of herba orostachyos, 10-20 parts of Chinese redbud skin, 10-20 parts of Amomum kravanh, 10-20 parts of Polygonum cuspidatum, 20-30 parts of chinese osbeckia herb and 200-700 parts of water. The decoction for treating nausea and vomiting caused by anesthesia has the characteristics of low cost, easy preparation, small side or toxic effects and remarkable curative effect, and is very suitable for clinical application.

The invention provides a production method of cepharanthin, which comprises the following steps: S1, taking 1kg by weight of stephania epigaea root powder, adding 0.6L 5% sodium carbonate for holding time of 2-3h; S2, adding 1.5L of benzene and soaking for 70-72 hours, filtering, then adding 1.5 L of benzene and soaking for 46-48 hours; S3, collecting benzene solution, adding 10% hydrochloric acid for extraction, adding sodium carbonate solution for alkalinization, and adding chloroform into the alkalinized solution for extraction; S4, adding anhydrous sodium sulfate and drying, recovering chloroform to obtain alkaloid; S5, adding 35ml of acetone for holding time of 2 hours, and adding 10ml of acetone and cleaning; S6, adding 2.5mL of benzene into acetone solution, standing for 10-12 hours, and adding 10mL of acetone and cleaning; and S7, adding chloroform, and eluting and concentrating through an aluminum chloride chromatographic column, to obtain cepharanthin. The recovery rate of the cepharanthin is high and is improved by improvement of the technology, and the technological parameters can be optimized.

The invention provides a medicament for treating gastric diseases. The medicament consists of the following components in part by weight: 1 to 4.5 parts of curcuma longa, 1 to 4.5 parts of zedoary, 1 to 4.5 parts of yellow ginger, 2 to 5 parts of A. maximum roxb., 1 to 5 parts of sassafras pith, 3 to 7 parts of Chinese fever vine, 1 to 3 parts of rhubarb, and 0.5 to 1.5 parts of stephania epigaea. The medicament can be used for treating gastric diseases, such as pain of the gastral cavity caused by acute and chronic gastritis, enteritis, antrum gastrititis, gastric ulcer, dyspepsia, cholecystitis, calculi and the like; and the clinical observation on curing effects and the researches on acute toxicity tests prove that the medicament does not generate toxic and side reactions, is safe and reliable and has obvious curing effect.

The invention relates to a long-acting plant deodorant. The long-acting plant deodorant is prepared from the following raw materials in parts by weight: 70-80 parts of probiotic liquid loaded on shell powder, 1-5 parts of ginger, 15-25 parts of lemon, 10-15 parts of sweet wormwood, 15-20 parts of rhizoma atractylodis, 5-10 parts of teasel root, 5-10 parts of wild gastrodia elata and 5-10 parts of stephania epigaea. The long-acting plant deodorant provided by the invention can rapidly and effectively eliminate environmental odor and inhibit reproduction of harmful original bacteria; decomposition of organic pollutants is promoted, BOD and COD are reduced, and water quality is purified; purification capability of a sewage treatment system is improved, aeration time is shortened, and output of sludge is reduced; decomposition of harmful substances in soil is accelerated, and a micro-ecological environment of the soil is thoroughly improved; and organic waste is subjected to composting treatment, and harmless cyclic utilization of resource is realized.

The invention discloses a traditional Chinese medicine composition for treating tympanites caused by qi stagnation and damp obstruction. The composition is composed of the following traditional Chinese herbals in parts by weight: 20 to 30 parts of embelia longifolia, 30 to 40 parts of lysimachia hemsleyana, 6 to 8 parts of thyme, 10 to 15 parts of dracocephalum heterophyllum, 8 to 12 parts of abutilon peniculatum, 10 to 15 parts of lathyrus davidii, 30 to 35 parts of fruit of common pratia, 8 to 10 parts of stephania excentrica, 8 to 12 parts of fruticulos moghania, 18 to 25 parts of trema cannabina, 18 to 25 parts of dayflower, 6 to 10 parts of peliosanthes minor, 18 to 25 parts of day lily, 25 to 30 parts of parnassia wightiana, and 18 to 25 parts of fragrant ainsliaea. The provided traditional Chinese medicine composition can effectively treat tympanites caused by qi stagnation and damp obstruction. The results of applications on patients in many years show that the effective rate can reach 100%, the curative effect is good, and no relapse happens after the curing.

The invention relates to a preparation method of a traditional Chinese medicine composition capable of promoting blood circulation to remove blood stasis, and stopping bleeding and relieving pain. The traditional Chinese medicine composition is prepared from following traditional Chinese medicine bulk drugs: rhizoma paridis, prepared kusnezoff monkshood root, sedum henryi diels, radix psammosilenes, veratrum taliensis Loes.f., Chinese yam, epigeal srephaia root, polygonum runcinatum Buch.-Harn. ex D.Don, rhizoma polygoni paleacei, semen strychni, and datura metel L. seed. The invention also relates to the preparation method and applications of the traditional Chinese medicine composition in clinic. The traditional Chinese medicine composition is reasonable and unique in formula, processing technology, and application; the preparation method is simple; clinical application is wide; and market value is high.

The invention discloses a special slow-release fertilizer for stephania epigaea and a preparation method thereof. The slow-release fertilizer comprises the following raw materials in parts by weight: 50 to 80 parts of urea, 40 to 50 parts of potassium phosphate, 30 to 45 parts of potassium dihydrogen phosphate, 5 to 15 parts of magnesium sulfate, 2 to 3 parts of zinc sulfate, 4 to 6 parts of sodium selenite, 3 to 5 parts of borax, 1 to 2 parts of ammonium molybdate, 4 to 7 parts of calcium superphosphate, 10 to 15 parts of tea bran, 20 to 30 parts of bagasse, 10 to 20 parts of expanded vermiculite, 15 to 20 parts of a coating agent and 0.1 to 0.5 part of a plant growth regulator, wherein the coating agent is montmorillonite and starch; the plant growth regulator is one or freely proportional mixture of two of sodium nitrophenolate and diethyl aminoethyl hexanoate. The slow-release fertilizer for the stephania epigaea has the advantages of complete nutrition, good slow-release effect, high utilization rate, low cost, simple preparation, no environmental pollution and the like, as well as good economic benefits; the yield of the stephania epigaea can be remarkably improved, the alkaloid content can be increased, and the large-scale production of the stephania epigaea can be well promoted.

The invention relates to a traditional Chinese medicine for treating pityriasis rubra pilaris. The traditional Chinese medicine is prepared from the following medicine materials in parts by weight: 15 parts of nothapodytes pittosporoides, 9 parts of patrinia heterophylla, 6 parts of heraeleum apaense, 12 parts of tripterospermum, 9 parts of membrane of hen egg, 9 parts of stephania hainanensis, 12 parts of scutellaria indica, 10 parts of phyllagathis elattandra diels, 12 parts of quassic root, 9 parts of teucrium pilosum, 15 parts of narrow leaf radix bupleuri herb and 9 parts of pogostemen nigrescens. Clinical trials prove that the traditional Chinese medicine is capable of treating the pityriasis rubra pilaris safely and effectively.

The invention provides a tissue culture breeding method of stephania epigaea high in cycleanine and cepharanthine content. The method includes the following steps that after being selected and sterilized, stephania epigaea explants are inoculated to an axillary bud induction culture medium, and obtained axillary buds are cut off and transferred to a culture medium for bud callus induction; then, bud calluses are transferred to an adventitious bud culture medium to induce differentiation of adventitious buds, and the number of the adventitious buds reaches 10-20 within 40 days; ancymidol is added to inhibit elongation of the buds and induce rooting, and after seedling hardening, transplanting is carried out, wherein the survival rate reaches 90% or above. The method is suitable for industrial production and has the advantages of being high in breeding speed and large in amplification factor, maintaining excellent characters of original varieties and the like.

The invention discloses a medicine for treating stomachache and a preparation method thereof. The medicine is primarily prepared from citronella, piper cubeba, rhizoma cyperi, ivy glorybind herb roots, fructus amomi, fructus piperis longi, Mangnolia officinalis, herb of moldavica dragonhead, herba millefolii, medicated leaven, girald daphne bark, wilson citrus seeds, fringed iris rhizome, acmellaoleracea, picrasma quassioides, Chinese sweet gum roots, trifoliate acanthopanax root root-bark, Baeckea frutescens roots, fructus evodiae, fermented soya beans ginger, waxberry roots, cotton tree barks, falcate dolichos root leaf, raw ratten, cactus, stephania epigaea, stephania epigaea and Sichuan Pepper in a certain weight ratio. The medicine disclosed by the invention has the functions of warming spleen and kidneys, promoting the circulation of qi and regulating the middle warmer, harmonizing stomach and refreshing spleen and regulating qi to alleviate pain and is quick to take effect andgood in curative effect for treating stomachache.

The invention belongs to the field of medicines and in particular relates to a cepharanthine-containing anti-inflammation medicine composition and a preparation method thereof. The anti-inflammation medicine composition provided by the invention comprises the following components in percentage by weight: 1-2% of a herba rabdosiae extract, 1-2% of a common andrographis herb extract, 2-3% of cepharanthine, 0.2-0.4% of essence oil, 0.1-0.3% of an emulsifier and 92.3-95.7% of purified water. Since an isoquinoline alkaloid compound, namely the cepharanthine extracted from delavay stephania roots, is added into the anti-inflammation medicine composition provided by the invention, the anti-inflammation performance of a medicine can be improved, no stimulation reaction can be caused for human bodies, and probability is provided for developing a type of novel anti-inflammation medicines.

The invention belongs to the field of Chinese patent medicine preparations and in particular relates to a medicine composition for treating rheumatoid arthritis. The medicine composition is prepared from the following raw materials in parts by weight: 10-50 parts of stephania epigaea, 10-50 parts of spatholobus suberctu; 5-40 parts of mistletoe, 5-40 parts of radix angelicae pubescentis, 5-40 parts of dipsacus asperoids, 5-20 parts of jasminum lanceolarium, 5-20 parts of caulis lonicerae and 3-10 parts of liquorice. Clinical experiments prove that the medicine composition can be taken for a long time without toxic or side effect or generation of tolerance and has quite good curative effect on the rheumatoid arthritis. The invention also discloses a preparation method and application of the medicine composition.

The invention discloses a traditional Chinese medicinal external lotion for treating flat wart. According to traditional Chinese medicine, the flat wart belongs to verruca plana, which is generally caused by dampness heat accumulated in skin as well as invasion of pathogenic toxin or lingering endogenous toxin, pathogenic heat due to stagnation, and stagnation of qi and blood, or the flat wart is caused by liver fire stirring frenetically, disharmony of qi and blood and stagnation in skin and tissue. The external lotion disclosed by the invention is prepared from the following traditional Chinese medicines: gynura segetum, szechwan indigo herb, pinnateleaf lilac root or branchlet, pericarpium canavaliae, manchurian tubergourd fruit, mapleleaf excoecaria seedling, hamilton clubmoss herb, beautiful phyllodium root, stephania epigaea, partedleaf violet herb and divaricate serpentroot herb and root. Upon clinical tests, the cure rate is 100%; and the external lotion is significant in curative effect.

The invention provides a seed breeding method of stephania epigaea high in cycleanine and cepharanthine content. The method includes the steps of collection and screening of high-content female and male stephania epigaea plants, hybridization, seed collection, seeding matrix preparation, seed treatment, sowing, strong seedling formation, disease and pest prevention, transplanting and the like. Bymeans of seed breeding, industrial production of the stephania epigaea high in medicinal component content can be effectively achieved, and the conflict between increasing market demands and gradual exhaustion of wild resources is relieved. The method has the advantages of being simple, easy to implement, low in cost, high in breeding speed and the like.

The invention relates to the field of pharmaceutical formulation, in particular to a traditional Chinese medicine for drug rehabilitation. The traditional Chinese medicine is characterized by being prepared from the following raw materials in percentage by weight: 7-11 percent of radix aucklandiae, 6-9 percent of smilax bockii warb, 5-7 percent of henbane, 5-8 percent of hibiscus sabdariffa, 6-9 percent of cirald daphne bark, 10-13 percent of rhodiola rosea, 5-8 percent of paederia scandens, 4-7 percent of corydalis decumbens, 4-7 percent of pteris multifida poir, 4-8 percent of carpesium abrolanoides linne, 3-6 percent of euphorbia kansui, 5-9 percent of cortex albiziae, 2-6 percent of ligusticum sinense, 3-6 percent of stephania epigaea, 3-6 percent of fructus alpiniae oxyphyllae and 1-3 percent of rhododendron molle. The bulk drug is soaked with water, decocted and then subjected to residue-removing to obtain filtrate. According to the traditional Chinese medicine disclosed by the invention, the cost is low; after a drug addict takes the traditional Chinese medicine for a short term, the effect of thoroughly removing the drug addiction without relapsing again can be achieved.

The invention provides a medicine composition for treating pig yellow fat disease and a preparation method of the medicine composition. The medicine composition comprises the following raw material herbs: arisaema lobatum, silkworm larva, dried orange peel, s sorghum, amomum tsaoko, rhizoma atractylodis, rhizoma nardostachyos, fructus viticis, pine nodular branches, clam powder, trichosanthes palmate, epigeal srephaia roots, zornia diphylla pers, rhopilema esculentum, ground seeweed, Chinese holly leaves, olgae, exucate of mussel, semen raphani, peruvian groundcherry herb, scentedros wood, grape roots, hyacinth bean flower, caesalpinia millettii, husked sorghum, cynanchum glaucescens, buddleia, lespedeza cuneata, centella, blumea, dandelion and peperomia blanda. The medicine composition is used for treating the pig yellow fat disease and has functions for eliminating the dampness and phlegm, strengthening the spleen and stomach, removing food retention, clearing away the internal heat and detoxifying; meanwhile, the resistance can be enhanced. The medicine composition has advantages of remarkable effect, appropriate herb selection, high quality, low price, safety, applicability, no medicine residue and the like.

The invention relates to a traditional Chinese medicine composition for treating repeated attack of gastric ulcer. The traditional Chinese medicine composition for treating repeated attack of gastric ulcer is prepared from the following raw materials: ceratostigma willmottianum stapf, cuttlebone, badger fat, trachycarpus nana, curculigo capitulate, grass mass goat stomach, ainsliaea lancifolia, fragrant sarcococca herb, swertia pseudochinensis, stephania epigaea, ikufuji and talc. Clinical trials prove that the traditional Chinese medicine composition can be used for safely and effectively curing gastric ulcer and is free of side effect.

The invention discloses a quality detection method of a stephania epigaea medicinal material. The method consists of: a. establishing a stephania epigaea standard fingerprint spectrum; b. determining the fingerprint spectrum of a to-be-tested stephania epigaea sample; c. comparing the fingerprint spectrum of the to-be-tested stephania epigaea sample with the stephania epigaea standard fingerprint spectrum, and screening Emilia sonchifolia medicinal material according with the Emilia sonchifolia standard fingerprint spectrum. The invention aims to provide important judgment basis for overall and comprehensive evaluation of medicinal materials through multi-component quality detection of stephania epigaea medicinal material, and ensures reliable quality and safe and reliable clinical efficacy. The method provided by the invention can be used for multi-component quality detection and control of stephania epigaea medicinal material, and provides important judgment basis for overall and comprehensive evaluation of the medicinal material.

The invention discloses an insecticide composition. The insecticide composition is prepared from the following raw materials in parts by weight: 10-20 parts of sage, 10-20 parts of pipewort, 5-15 parts of stephania epigaea, 15-25 parts of illicium anisatum, 15-25 parts of chilli sauce, 10-20 parts of matrine, 20-30 parts of ailanthus altissima juice, 2-6 parts of fenvalerate, 2-6 parts of ammonium phosphate, 1-3 parts of ferrous sulfate and 1-3 parts of trimethyl phosphite. The insecticide composition disclosed by the invention is low in cost and good in insecticidal effect, is mainly prepared from traditional Chinese medicinal materials and is combined with a certain amount of chemical agents and chemicals, so that the insecticide composition can play a greater insecticidal effect. The insecticide composition disclosed by the invention not only is harmless to plants but also produces no toxic or side effect to a human body, and various kinds of harms caused by the traditional pesticide to the human body can be completely avoided.

The invention discloses a Chinese herbal medicine for treating welling-abscess swelling. The Chinese herbal medicine is prepared from oroxylum indicum, calamint, Chinese lobelia, nervate twayblade herb, chloranthus holostegius, stephania epigaea, Desmodium oxyphyllum, corn silk, crotalaria sessiliflora, polygala amflra, swertia mileensis, polygonum cuspidatum, stachys geobombycis and water which are decocted according to a certain proportion. The Chinese herbal medicine provided by the invention has the efficacies of clearing away heat and toxic materials, diminishing inflammation and removing stasis and dredging the meridians and relieving pain through adopting a pure Chinese medicinal herb formula, can effectively treat the welling-abscess swelling and has no toxic or side effects.