26results about How to "Method stable" patented technology

The invention relates to a multi-target unmanned ship hunting method and system. The hunting method comprises the following steps: selecting a proper hunting unmanned ship for a target unmanned ship as a bid invitation person according to information of the hunting unmanned ship and the target unmanned ship; the bid invitation person captures unmanned ships around to issue information for bid invitation; the bidder bids, and calculates the distance between the bidder and the target unmanned ship and the wrap angle of the target unmanned ship; the bid invitation selects an optimal bidder combination as a distribution result according to the distance and the wrap angle; after all the target unmanned ships are distributed, the adjacent target unmanned ships carry out local exchange on the surrounding unmanned ships; performing hunting, wherein the hunting is divided into cooperative approaching and cooperative hunting; when the difference value between the distance between the hunting unmanned ship and the target unmanned ship and the surrounding radius Rs is smaller than a given threshold value epsilon and the total surrounding angle is larger than or equal to 360 degrees, hunting succeeds; and if a target unmanned ship is caught, task redistribution is carried out, and if all the target unmanned ships are caught successfully, the caught task is ended. According to the multi-target unmanned ship hunting method provided by the invention, task allocation of multiple unmanned ships is carried out through an improved contract net algorithm, the speed is increased, and the result is better; and meanwhile, the improved particle swarm optimization is combined with a staged hunting method to realize hunting control of multiple unmanned ships, the hunting success rate is improved, and the method is stable and good in adaptability.

The invention discloses a construction method and application of an HPLC (High Performance Liquid Chromatography) specific chromatogram of sunburn prevention and treatment cream, and relates to the technical field of pharmaceutical analysis. The sunshine prevention and treatment cream is composed of honeysuckle, perfoliote knotweed herb, sedum sarmentosum, dayflower, radix polygonati officinalis, lithospermum erythrorhizon, aloe, asparagus fern, lucid ganoderma, coix seed and bee pollen, and is one of representative products of Guizhou Miao medicine brands. The specific chromatogram of the sunshine prevention and treatment cream is established by adopting a high performance liquid chromatography, and the five medicinal materials including honeysuckle, lithospermum erythrorhizon, aloe, sedum sarmentosum and perfoliote knotweed herb can be identified at the same time. The HPLC characteristic chromatogram of the sunshine prevention and treatment cream established by the method can effectively characterize the quality of the sunshine prevention and treatment cream, and is beneficial to comprehensively monitoring the quality of medicinal materials. Meanwhile, the method has the advantages of being simple, convenient, stable, high in precision, good in reproducibility and the like, and the authenticity of the product can be rapidly and accurately identified.

The present invention relates to the technical field of detection of Chinese medicine formula granules, and discloses a detection method for orange and citrus aurantium formula granules. The method comprises first comparing the correspondence of characteristic peaks in the chromatograms of the test solution and the control medicinal material solution, and then further detecting the citrus aurantium formula granules according to the peak area ratio α1 of rutin naringin to naringin and the peak area ratio α2 of neohesperidin to hesperidin. The UPLC detection method has good accuracy, repeatability and separation, shortens the detection time, and is easy to operate. The present invention uses the simulated formula granule extraction solution as the evaluation benchmark, can accurately detect whether the formula granules are orange and citrus aurantium formula granules, makes up for the vacancy in the technical field of its origin identification, and the method can be used as an exclusive identification method for orange and citrus aurantium formula granules.

The invention relates to a detection method of a medicine for dispelling wind and eliminating dampness. The detection method comprises the following steps: thin-layer identification of a notopterygium root medicinal material, thin-layer identification of a radix angelicae pubescentis medicinal material, thin-layer identification of a radix saposhnikoviae medicinal material, thin-layer identification of ligusticum and ligusticum wallichii medicinal materials, and thin-layer identification of a honey-fried licorice root medicinal material. Through methodological investigation, the detection method has the effects of strong specificity, good durability, clear spots after thin layer expansion, satisfactory separation degree and the like, can effectively control the product quality condition, improves the product quality detection standard, and ensures the product quality.

The invention belongs to the technical field of active substance screening, and particularly relates to a method for high-throughput screening of a monoamine oxidase B inhibitor. The method comprises the following steps: incubating monoamine oxidase B and a drug-containing brain homogenate extracting solution, removing components which are not specifically bound by using an affinity ultrafiltration technology, eluting by using methanol to obtain a potential ligand, and identifying by using UPLC-Q-Exactive-MS (Ultra Performance Liquid Chromatography-Quantitative Exactive-Mass Spectrometry). Meanwhile, inactivated monoamine oxidase B is used as a control, interference of the control, false positive and non-specific binding is eliminated, the in-vitro monoamine oxidase B inhibition effect of the identification ligand is measured, and the result proves that the compound screened by using the affinity ultrafiltration-liquid chromatography-mass spectrometry technology has the monoamine oxidase B inhibition activity. The method disclosed by the invention is rapid, simple, convenient, stable, high in precision and good in reproducibility, and has a wide application prospect in the aspect of rapidly screening target compounds in natural medicines.

This invention relates to the field of alloy purification technology, specifically to a method, system, and aluminum alloy welding material for preparation of self-purifying aluminum alloy welding material. The method for preparing the self-purifying aluminum alloy welding material includes the following steps: cold pressing a mixture of aluminum alloy powder and refining agent powder to obtain a cold-pressed billet; hot pressing the cold-pressed billet to obtain a hot-pressed aluminum ingot; removing impurities from the surface of the hot-pressed aluminum ingot, followed by preheating to obtain a preheated ingot; and extruding the preheated ingot into wire. This invention uses powder metallurgy to prepare aluminum alloy welding material with self-purifying function, extending the degassing method of aluminum alloy smelting to the aluminum alloy welding process. This relaxes the strict requirements on the hydrogen content of the aluminum alloy base material, achieving a weld with lower hydrogen content. The method is more efficient, more stable, and less expensive.

The present invention discloses a flow cytometry quantitative detection reagent, a kit and a detection method for semen leukocyte population. The detection reagent and the kit include: 1) a sample treatment agent: containing Na2HPO4, KH2PO4, and NaCl; 2) a sample diluent: containing Na2HPO4, KH2PO4, NaCl and KCl; 3) a sample separation agent: containing polysucrose and diatrizoate; 4) an antibody: an IgG type monoclonal antibody of anti-human CD45 with a fluorescent marker; 5) a sample fixative: containing paraformaldehyde. The detection method of the present invention is based on the principle of flow cytometry, using a sample treatment agent to remove impurities and non-target cells in semen, and then using a leukocyte CD45 antibody to specifically bind to the surface of leukocytes in semen, and finally using a flow cytometer to detect the specific marker fluorescence, thereby obtaining the number of leukocytes. This method is detected and recorded by a machine, which is more objective and stable than the peroxidase method, and is easy to standardize and has strong specificity; the antibodies used for staining are stable in nature, have a long storage time, and are convenient to use.

The invention relates to a magnesium-based hydrogen storage material and a preparation method thereof, and belongs to the technical field of hydrogen storage alloy materials and preparation thereof. The hydrogen storage material is an Mg-5Ni alloy with Sm powder uniformly distributed on the surface layer and an amorphous / nanocrystalline structure in the interior. The Sm powder is wrapped by the surface layer of the Mg-5Ni alloy to form composite powder of a core-shell structure; the hydrogen storage material is prepared from Mg-5Ni alloy powder and Sm powder as raw materials, and the raw materials are mixed and then subjected to dry ball milling. The hydrogen absorption and desorption kinetics of the existing magnesium-based hydrogen storage material can be effectively improved, the hydrogen desorption activation energy of the magnesium-based hydrogen storage material is reduced, and the problem that a solid additive is difficult to uniformly distribute on the surface is solved.

The application discloses a kind of characteristic chromatogram detection methods of Qinggan Jieyu granules. After the solvent and microporous filter membrane treatment of Qinggan Jieyu granules, different batches of test solution are obtained, and the chromatogram of each is obtained by preparing the reference solution; the chromatogram of different batches of test solution and reference solution is combined to obtain the characteristic chromatogram and characteristic chromatographic peak of control, and then the relative retention time of the characteristic chromatographic peak and reference berberine hydrochloride peak solution is used to obtain the relative retention time of the control characteristic chromatogram as the specified value; the chromatogram is obtained by detecting the to-be-tested granules, and S peak correction is carried out, and the detection result is obtained by comparing the specified value of relative retention time. The characteristic chromatogram detection method of Qinggan Jieyu granules established by the application is simple in operation, reliable in result, high in stability and precision, and good in repeatability; the characteristic chromatogram of Qinggan Jieyu granules provided by the application can comprehensively and effectively control the quality of the preparation, and ensure the stability, reliability and safety of the preparation.

The invention provides a construction method and application of a pepper medicinal material UPLC characteristic spectrum. The construction method of the pepper medicinal material UPLC characteristic spectrum comprises the following steps: taking hyperoside, hydroxyl-alpha-sanshool and hydroxyl-beta-sanshool to prepare a mixed reference substance solution; preparing a test solution from a pepper medicinal material; and respectively carrying out ultra-high performance liquid chromatography analysis on the mixed reference substance solution and the test solution, and constructing the pepper medicinal material UPLC characteristic spectrum. The construction method of the pepper medicinal material UPLC characteristic spectrum has the advantages of being rapid, stable and high in specificity, the obtained pepper medicinal material characteristic spectrum shows 11 characteristic peaks, spectrum information is rich, the chemical component characteristics of the pepper medicinal material can be fully displayed, a comprehensive and effective rapid evaluation method is provided for quality control of the pepper medicinal material, and the method is suitable for popularization and application. The method can realize identification of different primitives and counterfeit products of Chinese prickly ash, and has a wide application prospect.

The present invention discloses the use of peripheral blood leukocyte RNA combined markers in the preparation of a kit for detecting or diagnosing early primary gallbladder cancer. The present invention is based on peripheral blood leukocyte RNA markers for detection. The marker is a liquid biopsy biomarker that is more sensitive, stable, non-invasive, and requires less sample volume, which is more acceptable to patients. Its successful development will help the diagnosis of gallbladder cancer. The etiology of primary gallbladder cancer is complex. Compared with a single molecular marker, the present invention evaluates the accuracy of the test sample from two dimensions of abnormally high expression and low expression, which can reduce the error caused by individual expression differences of a single indicator to a certain extent, making the result more accurate.

The application discloses a kind of continuous flow photocatalytic decarboxylation preparation biological hydrocarbon method, belong to the technical field of biofuel preparation.The method includes the following steps: high fatty acid compound, hydrogen atom transfer catalyst and acridine photocatalyst are dissolved in organic solvent, and mixed solution is obtained;The mixed solution is passed into circulating continuous flow light reactor, and photocatalytic decarboxylation reaction is carried out at room temperature for 12-24 hours, and reaction liquid is obtained;Reaction liquid is separated by reduced pressure distillation, and the biological hydrocarbon compound after decarboxylation is obtained.The application uses continuous flow light reactor to strengthen mass transfer and heat transfer efficiency, solves the problem that light penetration depth is limited in traditional batch photoreactor, and reaction is not uniform;Metal-free catalytic system is used, and the use of noble metal and potential residual risk is avoided.The method has mild reaction condition, higher product yield, good atom economy, and for unsaturated high fatty acid, olefin configuration can be maintained before and after decarboxylation, and has good industrial application prospect.

The invention provides a wind power tower drum transportation system and method, the wind power tower drum transportation system comprises a base assembly and a plurality of connecting seat components, the base assembly is fixedly connected to a transportation ship, each connecting seat component is arranged at one end of one wind power tower drum, the connecting seat components are detachably connected with the base assembly, and the base assembly is fixedly connected with the base assembly. The wind power towers can be vertically fixed to the transport ship in an array mode through the base assemblies and the connecting base parts. The wind power tower barrel fixing device has the advantages that the tower barrel fixing mode is simple and firm, and the wind power tower barrel loading capacity of a ship is greatly improved on the premise that transportation safety is guaranteed; the base assembly and the connecting seat component can also be used for storing the wind power tower barrel on the shore, the tower barrel can be effectively fixed, and the space needed by storage can be reduced; the system is simple in structure, convenient to install, capable of being used for tower barrels of different sizes and high in universality; and the tower drum loading and unloading efficiency is improved.

The present invention provides a quality control method for a Ruren medicinal material and a Ruren formula granule, the quality control method comprising the following steps: extracting the Ruren medicinal material or the Ruren formula granule to prepare a test solution; mixing protocatechuic acid and an ethanol aqueous solution to prepare a reference solution; respectively detecting the test solution and the reference solution by high performance liquid chromatography to obtain the content of protocatechuic acid in the Ruren medicinal material or the Ruren formula granule and the characteristic spectrum of the Ruren medicinal material or the Ruren formula granule. The present invention constructs an HPLC characteristic spectrum of the Ruren medicinal material and the Ruren formula granule, fully demonstrating the chemical composition characteristics of the Ruren medicinal material and the Ruren formula granule; at the same time, the present invention establishes an HPLC content determination method for protocatechuic acid in the Ruren medicinal material and the Ruren formula granule, which is simple to operate, high in accuracy and good in stability.

The invention provides a rolapitant fat emulsion injection as well as a preparation method and application thereof, and belongs to the technical field of biological medicines. The rolapitant fat emulsion injection provided by the invention comprises an oil phase component and a water phase component, the oil phase component comprises 0.1-1% of rolapitant, 0.1-5% of a cosolvent, 5-10% of vegetable oil and 1-2% of an emulsifier; the water phase component comprises 1-2.25% of an osmotic pressure regulator, 0.01-1% of an auxiliary emulsifier and the balance of water; the water is used, so that the total mass percentage of the oil phase component and the water phase component is 100%. According to the rolapitant fat emulsion injection disclosed by the invention, the use of high-concentration HS-15 with a hemolysis risk is avoided, and auxiliary materials with good safety are adopted, so that the potential toxic and side effect risk is reduced, the vomiting of a patient can be quickly relieved, and the clinical medication risk is remarkably reduced.

The invention relates to the field of coal liquefaction, in particular to a preparation method and system of coal-based heat-conducting oil, coal-oil slurry is prepared by mixing pulverized coal and a hydrogen-donating solvent, and the coal-based heat-conducting oil is finally prepared by the steps of direct coal liquefaction, hydrotreating, two-time oil-gas separation, light and heavy component separation, steam stripping rectification, reduced pressure distillation and the like in sequence. The invention also provides a corresponding preparation system which integrates core equipment such as a mixing tank, a coal liquefaction reactor, a hydrogenation reactor, a fractionating tower, an oil-gas separator, a light-heavy separator, a stripping tower and a vacuum tower. A new process route for preparing the heat conduction oil is developed, a traditional preparation method for generating the heat conduction oil by extracting aromatic hydrocarbon from petroleum-based light oil through catalytic cracking is broken through, and the obtained heat conduction oil has high initial boiling point and flash point and stable heat conduction capability at high temperature.

The application belongs to the technical field of biomedicine, and specifically discloses a squamous cell carcinoma antigen determination kit and application, which comprises anti-reagent A, anti-reagent B and magnetic micro-particle reagent, wherein the anti-reagent A is a biotin-labeled squamous cell carcinoma antigen antibody; the anti-reagent B is an alkaline phosphatase-labeled squamous cell carcinoma antigen antibody; the squamous cell carcinoma antigen determination kit can effectively detect the concentration of squamous cell carcinoma antigen (SCC) in serum and plasma samples, and is mainly used for the treatment monitoring of cervical cancer, non-small cell carcinoma and the like, and has a wide application prospect.

The invention belongs to the field of biological activity detection, and particularly relates to a detection method for insulin analogue stimulated cell glycogen synthesis as well as a product and application thereof. The cells are 3T3L1 precursor cells subjected to induced differentiation, and the induced differentiation comprises the steps of inducing for 9 days by using a cell differentiation culture medium (d), and continuing to differentiate for 3 days by using an adipose cell maintenance culture medium. The insulin analogue is diluted through a diluent, the diluent is a GM culture medium added with dexamethasone, and the final concentration of the dexamethasone is 0.5-2 [mu] M. The method provided by the invention can quantify the insulin analogue, and is simple and safe to operate, good in stability and reproducibility and high in sensitivity.

The application provides a kind of method and system for dissimilar metal molten pool flow visualization based on synchrotron radiation.The method comprises preparing dissimilar metal sample;Clamping dissimilar metal sample in sample clamping table, adjusting the X-ray incident direction of synchrotron imaging device to penetrate dissimilar metal sample;Irradiate dissimilar metal sample with laser;Transmitting imaging of mixed molten pool is carried out using synchrotron radiation source, and a sequence of transmission imaging is obtained;The transmission imaging sequence is analyzed to obtain the dynamic migration and flow pattern image information and data of the metal in the mixed molten pool.The method does not need to introduce tracer particles or bubbles, and does not change the intrinsic flow of the molten pool;The imaging contrast is high, the space-time resolution is high, the real and repeatable molten pool internal flow field information can be obtained, and it is suitable for the molten pool dynamics research and mechanism analysis in the process of laser welding and additive manufacturing, to provide reliable data support for molten pool flow model verification and process optimization.

The invention discloses a construction method of a specific chromatogram of a standard decoction or formula granule of flos magnoliae officinalis, which comprises the following steps: preparing a reference substance solution which comprises a reference substance solution of a reference medicinal material and a reference substance solution of a reference substance, the reference substance solution comprises a magnolin B reference substance, a magnolol reference substance and a honokiol reference substance; preparing the officinal magnolia flower standard decoction or formula granules into a test solution; a preset amount of the reference substance solution and the test solution are taken and injected into a liquid chromatograph, the liquid chromatograph takes octadecylsilane chemically bonded silica as a filler, acetonitrile as a mobile phase A and a phosphoric acid solution as a mobile phase B for gradient elution, and the characteristic chromatogram is established. The method can provide a data basis for quality control of standard decoction or formula granules and medicinal materials of flos magnoliae officinalis, and ensures the stability and controllability of product quality.

The present invention belongs to the field of unmanned driving technology, and specifically discloses a synchronous positioning and mapping method based on heterogeneous multimodal data fusion. The present invention solves the problems existing in traditional positioning and mapping methods when applied to complex environments such as tunnels by means of data fusion of millimeter-wave radar and lidar, filtering of dynamic objects, enhancement of loop detection, and global consistency optimization, and provides a more accurate, stable, and adaptable positioning and mapping method. The method of the present invention can be applied to the positioning and mapping of autonomous mobile devices such as drones and robots in dynamic environments such as tunnels, and can provide stable positioning and map building capabilities in the presence of dynamic obstacles (such as construction equipment, vehicles, etc.) and low light conditions, significantly improving the positioning accuracy, map building capabilities, and system stability of drones or robots in complex dynamic environments.

The invention belongs to the field of preparation and application of inorganic functional composite materials, and relates to a multi-shell composite catalytic material as well as a preparation method and application thereof. The Zn2MnO4 / CdS composite material is a Zn2MnO4 / CdS composite material, the Zn2MnO4 is of a nano multi-shell hollow sphere structure, the CdS is nanoparticles, and the surface of the Zn2MnO4 is coated with a plurality of CdS nanoparticles. The catalytic material not only has a higher specific surface area and provides more surface active sites, but also can enhance refraction and reflection of light, so that the utilization efficiency of the light is improved. Meanwhile, a heterojunction with an inner electric field is constructed between the Zn2MnO4 / CdS composite materials, so that efficient separation of photon-generated carriers can be promoted, spatial separation holes and electrons with high oxidation-reduction capacity are generated, and efficient photocatalytic hydrogen production performance is achieved. Compared with single Zn2MnO4, the multi-shell composite catalytic material provided by the invention has more excellent performance of photocatalytic decomposition of water to produce hydrogen.

The present invention belongs to the technical field of quality detection of traditional Chinese medicine, and specifically relates to the establishment and detection method of the characteristic spectrum of Dan'e Fukang decoction. The method for establishing the characteristic spectrum is as follows: a. Accurately weigh chlorogenic acid, ferulic acid, and salvianolic acid B reference substances, mix them, and then add methanol solution to dissolve them to obtain a reference solution; b. Accurately weigh Dan'e Fukang decoction, add water for ultrasonic extraction, centrifuge, take the supernatant and pass it through a macroporous adsorption resin, elute with water and then with ethanol solution, collect the eluate, evaporate to dryness, add water, filter, and take the subsequent filtrate to obtain a test solution; c. Use ultra-high performance liquid chromatography to measure the test solution and the reference solution, and obtain a characteristic spectrum consisting of 11 common characteristic peaks. This method constructs the characteristic spectrum of Dan'e Fukang decoction, which provides a scientific experimental basis for the study of the quality evaluation system of Dan'e Fukang decoction; and also establishes a method for rapid and comprehensive detection of the effective ingredients of Dan'e Fukang decoction.

The invention discloses a method for constructing a characteristic spectrum of Poria cocos, red Poria cocos and Poria cocos peel, comprising the following steps: preparing a reference solution, wherein the reference solution includes a uridine reference, an adenosine reference and a guanosine reference; taking Poria cocos medicinal materials, red Poria cocos medicinal materials or Poria cocos peel medicinal materials to prepare a test solution; taking a preset amount of the test solution and the reference solution respectively, injecting them into a liquid chromatograph for determination, wherein the liquid chromatograph uses octadecylsilane bonded silica gel as a filler, methanol as a mobile phase A, and potassium dihydrogen phosphate solution as a mobile phase B for gradient elution to obtain a characteristic spectrum. The invention has good reproducibility, is accurate and reliable, and can quickly and accurately identify medicinal materials from different parts of Poria cocos based on water-soluble components.

The invention discloses a structure-oriented dispersing agent, a flaky magnesium hydroxide nano-material and preparation and application of the flaky magnesium hydroxide nano-material. A preparation method of the structure-oriented dispersing agent comprises the steps that S1, sodium alkyl benzene sulfonate is placed in a reaction container, and methyl alcohol is added to serve as a solvent; s2, slowly dropwise adding formaldehyde at a certain reflux temperature and a certain rotating speed for reaction; and S3, after the reaction is finished, removing the solvent through reduced pressure distillation and vacuum drying. The structure-oriented dispersing agent can assist the formation of a two-dimensional sheet structure of a nano material in the process of preparing nano magnesium salt by a coprecipitation method, and meanwhile, the structure-oriented dispersing agent and the sheet magnesium salt nano material can form a synergistic effect, so that the oil-water interfacial tension is effectively reduced, and the structure-oriented dispersing agent can be used as an oil displacement system to be applied to oil reservoir development. The preparation process is simple, the raw material source is wide, the production cost is low, the prepared flaky magnesium hydroxide nano material is good in oil-water interfacial activity, the oil-water interfacial tension can be effectively reduced, and the crude oil recovery rate is improved.

The invention belongs to the technical field of traditional Chinese medicine quality detection, particularly relates to a new technology of combining an ultra-high performance liquid chromatograph-diode array detector with multi-time wavelength sectional switching, and develops a specific chromatogram construction method and a detection method of pain tincture. The method specifically comprises the following steps: a, preparation of a reference substance solution: taking a proper amount of bergenin, brachypekinin A, rutin, cinnamaldehyde, paeonol and aconitine reference substances, and adding a solvent for dissolving to obtain the reference substance solution; b, preparation of a test solution: taking the pain tincture, and adding an ethanol solution to prepare the test solution; c, detection: injecting the reference solution and the test solution into an ultra-high performance liquid chromatograph for detection, taking the specific chromatogram of the reference solution as a reference chromatogram, selecting common peaks from the specific chromatogram of the test solution, constructing the specific chromatogram of the pain-relieving tincture, and determining 13 common peaks; meanwhile, the invention also provides a rapid and comprehensive detection method of the pain tincture.