2 results about "Mallotus" patented technology

This invention belongs to the field of pharmaceutical technology and relates to eight glycoside compounds extracted and isolated from the dried leaves of *Picrasma quassioides* Benn, a plant belonging to the genus *Picrasma* in the family Simaroubaceae. The compounds were obtained using chromatographic methods including silica gel chromatography, HP20 column chromatography, ODS column chromatography, and HPLC. This invention also relates to the acetylcholinesterase inhibitory activity of compounds 1-8 and their pharmaceutical uses. The preparation method of this invention is simple, reproducible, and of high purity.

The invention provides an anti-atherosclerosis lipidosome carrier drug and a preparation method thereof, and belongs to the technical field of biological pharmacy, the lipidosome carrier drug is prepared by taking tussah peptide, premna microphylla leaf flavonoid glycoside, clausena lansium leaf polysaccharide and troxerutin as active ingredients. The antheraea pernyi peptide is a product between 1kDa and 5kDa obtained by extracting protein from antheraea pernyi and sequentially carrying out enzymolysis by bacillus subtilis protease and pepsin. The premna microphylla leaf flavonoid glycoside is prepared by performing enzymolysis and water extraction on premna microphylla leaves and then purifying the premna microphylla leaves through an HPD-600 macroporous adsorption resin column. The clausena lansium leaf polysaccharide is prepared by the following steps: extracting clausena lansium leaves with water, precipitating with ethanol, redissolving, and purifying through a DEAE-52 cellulose column and a Sephadex G-100 gel column in sequence. All the components aim at key pathological links of atherosclerosis respectively, and the core advantages of high efficiency, safety and stability are achieved through multi-component synergistic compatibility and closed-loop optimization of a fine preparation process.