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Probiotics capable of improving microecological balance of upper respiratory tracts and preparation method thereof

A technology of probiotic preparations and ecological balance, which is applied to respiratory diseases, medical preparations containing active ingredients, and pharmaceutical formulas to achieve the effects of stabilizing microbial populations, preventing upper respiratory tract infections, and being easy to use

Inactive Publication Date: 2016-12-07
CHENGDU KAISHENG BIOLOGICAL SCI & TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

But so far, there is no further detailed introduction of Streptococcus A and other probiotics in adjusting the microecological balance of the upper respiratory tract

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0033] A probiotic preparation for improving the micro-ecological balance of the upper respiratory tract, which is composed of Streptococcus Group A bacteria powder, Tricinococcus bacteria powder, Bifidobacterium infantis and Lactobacillus acidophilus. The percentage by weight is 30%; The number of viable bacteria in the probiotic preparation is 10 10 .

Embodiment 2

[0035] A probiotic preparation for improving the micro-ecological balance of the upper respiratory tract, consisting of Group A Streptococcus bacteria powder, Quercinia bacteria powder, Bifidobacterium longum, Bifidobacterium infantis and Lactobacillus acidophilus, the Group A Streptococcus bacteria Powder accounts for 60% by weight of the probiotic preparation; the number of viable bacteria in the probiotic preparation is 10 15 .

Embodiment 3

[0037] A probiotic preparation for improving the micro-ecological balance of the upper respiratory tract, which is composed of Streptococcus Group A bacteria powder, Tricinococcus bacteria powder, Bifidobacterium breve and Lactobacillus acidophilus. The percentage by weight is 50%; The number of viable bacteria in the probiotic preparation is 10 12 .

[0038] The preparation method of the probiotic preparation in the present embodiment is as follows:

[0039] A. Preparation of Streptococcus A bacteria powder

[0040] After adding whey protein and fructooligosaccharides to the liquid medium, autoclave at 121°C for 20 minutes, cool to 37°C, inoculate group A Streptococcus, and culture continuously at 37°C until the bacterial content reaches 1×10 5 After / ml, centrifuge with a low-temperature high-speed centrifuge to obtain wet thalline;

[0041] Suspend the wet bacteria in skimmed milk powder with a pH of 4.8 and a mass concentration of 20%, mix well and then freeze-dry to ob...

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PUM

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Abstract

The invention discloses probiotics capable of improving microecological balance of upper respiratory tracts and a preparation method thereof, belonging to the technical field of biology. The probiotics comprise alpha streptococcus powder, micrococcus tetragenus powder, bifidobacterium powder and lactobacillus acidophilus powder, wherein the alpha streptococcus powder accounts for 30-60% of the probiotics by weight; the viable count of the probiotics is 10<10>-10<15>. The probiotics not only are beneficial to stabilization of microfloras of respiratory tracts and can effectively prevent upper respiratory tract infections and avoid upper respiratory tract diseases but also can still play a role of probiotics, regulate microflora balance of gastrointestinal tracts and enhance the resistance of human bodies to foreign pathogenic bacteria after the probiotics powder enter the gastrointestinal tracts with saliva swallowing.

Description

technical field [0001] The invention relates to a probiotic preparation, in particular to a probiotic preparation for improving the micro-ecological balance of the upper respiratory tract and a preparation method thereof, belonging to the field of biotechnology. Background technique [0002] The lower respiratory tract of a healthy human body, especially the part below the small bronchi, the lungs and the chest cavity are completely sterile. The nasopharynx, as the beginning part of the respiratory tract, is the passage connecting the lower respiratory tract with the outside world. Any pathogenic bacteria entering the human body must first Colonization of the nasopharynx can then further cause corresponding pathological reactions in the body. The nasopharynx is sterile when the baby is born. Through the close contact with the air environment and the surrounding people, general aerobic bacteria such as Streptococcus A and Staphylococcus albus appear in the nasopharynx and thr...

Claims

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Application Information

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IPC IPC(8): A61K35/747A61K9/12A61P11/00A61P1/00
CPCA61K35/744A61K9/0073A61K35/741A61K35/745A61K35/747A61K47/36A61K2300/00
Inventor 林洋刘健章太永
Owner CHENGDU KAISHENG BIOLOGICAL SCI & TECH
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