A Method for Fornix White Matter Segmentation Based on Fusion of fMRI and DTI

A white matter and dome technology, applied in the field of image processing, can solve the problem of less involvement

Active Publication Date: 2019-05-07
XI AN JIAOTONG UNIV
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Problems solved by technology

However, the current research and understanding of the sub-branches of the fornix white matter is rarely involved. The segmentation of the fornix white matter sub-branches is of great significance for the prevention and targeted treatment of memory-related mental diseases.

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  • A Method for Fornix White Matter Segmentation Based on Fusion of fMRI and DTI
  • A Method for Fornix White Matter Segmentation Based on Fusion of fMRI and DTI
  • A Method for Fornix White Matter Segmentation Based on Fusion of fMRI and DTI

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Embodiment Construction

[0019] The present invention is described in detail below in conjunction with accompanying drawing.

[0020] The present invention is a method for segmenting fornix white matter based on fMRI and DTI fusion, and the specific steps are as follows:

[0021] (1) Preprocessing fMRI and DTI magnetic resonance imaging data. Preprocessing includes functional magnetic resonance imaging and diffusion tensor imaging. fMRI preprocessing includes head segmentation, time correction, head movement correction, spatial smoothing, time domain bandpass filtering, linear drift removal and redundancy removal. DTI preprocessing includes steps such as eddy current deformation correction, scalping operation, calculation of diffusion tensor of each voxel and calculation of FA, MD and other diffusion parameters.

[0022] The fMRI data preprocessing was completed by writing Batch files (data batch processing) based on AFNI and FSL software under the Linux system Ubuntu14.04. For preprocessing see fi...

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Abstract

A method for fornix white matter segmentation based on fusion of fMRI and DTI, including preprocessing of fMRI and DTI magnetic resonance image data, regional segmentation of hippocampal brain regions based on resting-state functional connectivity, ROI selection, based on hippocampal subregions and thalamus The four steps of fornix white matter segmentation of interwhite matter fiber tract tracing technology, the innovation of the present invention is that it proposes to segment the hippocampus brain region through fMRI functional connection and use the segmented sub-region as the seed point, and use the thalamus as the target brain region to carry out A new method for segmenting the white matter of the fornix by tracing white matter fibers; the invention combines the information of the function and structure of the human brain to segment the white matter of the fornix. The idea is novel, the process is simple, and it has important scientific research and clinical value.

Description

technical field [0001] The invention belongs to the technical field of image processing, and specifically relates to a method for segmenting fornix white matter based on the fusion of fMRI and DTI, in particular to segmenting the hippocampal brain region through fMRI functional connection, using the segmented sub-region as the seed point, and using the thalamus as the target brain region. The method of segmenting the white matter of the fornix by tracing white matter fibers in the region. Background technique [0002] fMRI is one of the main non-invasive methods to study brain activity and brain function, with millimeter-level spatial resolution. The development of fMRI method has made a breakthrough in the study of brain cognitive function, and it has become an important tool for neuroscience to explore the neural mechanism of the human brain. DTI takes advantage of the anisotropic characteristics of water molecule diffusion in heterogeneous tissues. By applying multi-dire...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): G06T7/11G06T3/40
CPCG06T3/4038G06T2207/10088G06T2207/20221G06T2207/30016
Inventor 林盘窦顺阳王雪丽
Owner XI AN JIAOTONG UNIV
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