Vitamin D binding peptide and application thereof

Abstract

The invention discloses a vitamin D binding peptide and application thereof. Sequence motif of the vitamin D binding peptide is LFLLLF. The vitamin D binding peptide and the application have the advantages that the vitamin D binding peptide can be used as an antigen for effectively inducing antibodies for vitamin D binding proteins, accordingly, the vitamin D binding proteins can be accurately quantified, and the in-vivo vitamin D contents can be quantitatively detected.

Description

technical field [0001] The present invention relates to a polypeptide, in particular to a vitamin D binding peptide and its application. Background technique [0002] Vitamin D is a fat-soluble vitamin composed of long hydrocarbon chains or fused rings, and is a steroid derivative. It promotes normal bone formation, enhances the absorption of calcium, phosphorus, iron and zinc ions in the small intestine and kidneys, and regulates the health of all muscles, including the bones and heart, immune response, blood sugar and insulin levels in the body. For humans, the two most important forms of vitamin D that are closely related to physical health are vitamin D2 and vitamin D3, also known as ergocalciferol and cholecalciferol, respectively [1] . Ergocalciferol and cholecalciferol can be obtained from diet and supplements [1][2][3] , but few foods contain natural sources of calciferol and cholecalciferol. In fact, no matter how well-nourished adults are, they are unlikely to ...

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Problems solved by technology

However, long-term or high-dose use of vitamin D can increase the concentration of serum 25(OH)VD and hypercalcemia, and clinically show symptoms of poisoning

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