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Traditional Chinese medicine composition capable of preventing and treating chronic renal failure, its preparation method and application

A technology for chronic renal failure and composition, which is applied in the field of traditional Chinese medicine composition and its preparation with the effect of preventing and treating chronic renal failure, and can solve the problems of inability to effectively remove protein-bound uremic toxin and low clearance rate of protein-bound uremic toxin, etc. To achieve the effect of reducing the generation, relieving clinical symptoms, and reducing the accumulation in the body

Active Publication Date: 2019-07-09
NANJING UNIVERSITY OF TRADITIONAL CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] At present, the removal of uremic toxins mainly uses dialysis to remove water-soluble small molecule uremic toxins in the blood. However, none of these methods can effectively remove protein-bound uremic toxins in the blood; Works well, but poor clearance for protein-bound uremic toxins

Method used

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  • Traditional Chinese medicine composition capable of preventing and treating chronic renal failure, its preparation method and application
  • Traditional Chinese medicine composition capable of preventing and treating chronic renal failure, its preparation method and application
  • Traditional Chinese medicine composition capable of preventing and treating chronic renal failure, its preparation method and application

Examples

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Effect test

Embodiment 1

[0035] 1. A traditional Chinese medicine composition having the effect of preventing and treating chronic renal failure, which is made of the following raw materials in parts by weight: 10 parts of hollyhock, 3 parts of astragalus, 5 parts of knotweed, and 2 parts of turmeric.

[0036] 2. A preparation method of a traditional Chinese medicine composition having the effect of preventing and treating chronic renal failure, comprising the following steps:

[0037]Take 10 parts of hollyhock flowers, 3 parts of astragalus, 5 parts of knotweed, and 2 parts of turmeric medicinal materials into the reflux extraction tank, add 20 times the amount of medicinal materials for soaking in water, and start heating after all the medicinal materials are fully moistened. When heated to complete boiling, keep boiling and extract After 2 hours, filter, add 15 times the volume concentration of 95% ethanol to the filter residue, and continue heating. After complete boiling, keep boiling for 2 hours,...

Embodiment 2

[0039] 1. A traditional Chinese medicine composition having the effect of preventing and treating chronic renal failure, which is made of the following raw materials in parts by weight: 10 parts of hollyhock, 10 parts of astragalus, 10 parts of knotweed, and 3 parts of turmeric.

[0040] 2. A preparation method of a traditional Chinese medicine composition having the effect of preventing and treating chronic renal failure, comprising the following steps:

[0041] Take 10 parts of hollyhock flower, 10 parts of astragalus, 10 parts of knotweed, and 3 parts of turmeric into the reflux extraction tank, add 20 times the amount of water for soaking, and start heating after all the herbs are fully wet. When heated to a complete boil, keep boiling to extract After 2 hours, filter, add 15 times the volume concentration of 95% ethanol to the filter residue, and continue heating. After complete boiling, keep boiling for 2 hours, filter, combine the filtrates, and concentrate to obtain a c...

Embodiment 3

[0043] 1. A traditional Chinese medicine composition having the effect of preventing and treating chronic renal failure, characterized in that it is made of the following raw materials in parts by weight: 10 parts of hollyhock, 3 parts of astragalus, 3 parts of Polygonum cuspidatum, and 0.3 part of turmeric.

[0044] 2. A preparation method of a traditional Chinese medicine composition having the effect of preventing and treating chronic renal failure, comprising the following steps:

[0045] Take 10 parts of hollyhock flowers, 30 parts of astragalus, 15 parts of knotweed and 3 parts of turmeric into the reflux extraction tank, add 15 times the amount of water for soaking, and start heating after all the herbs are fully wet. When heated to a complete boil, keep boiling to extract After 3 hours, filter, add 10 times the volume concentration of 95% ethanol to the filter residue, continue heating, and keep boiling for 2 hours, filter, combine the filtrates, and concentrate to obta...

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Abstract

The invention discloses a traditional Chinese medicine composition having efficacy of preventing and treating chronic renal failure. The traditional Chinese medicine composition is prepared from 10 parts of abelmoschus manihot, 3-30 parts of radix astragali, 3-15 parts of polygonum cuspidatum and 0.3-3 parts of curcuma longa. On the basis of medical formulation compatibility theories of China and a lot of experiment studies, the traditional Chinese medicine composition of abelmoschus manihot, radix astragali, polygonum cuspidatum and curcuma longa is screened out. Experiment results show that the traditional Chinese medicine composition has good effects on reducing generation of protein-bound urotoxin precursor in intestinal tract and reducing in-vivo accumulation of urotoxin, has good protecting and improving effects on chronic renal failure and can relieve clinical symptoms of chronic renal failure. The traditional Chinese medicine composition has important application prospect in clinical treatment of chronic renal failure.

Description

technical field [0001] The invention relates to a traditional Chinese medicine composition, in particular to a traditional Chinese medicine composition capable of preventing and treating chronic renal failure, a preparation method and application thereof. Background technique [0002] Chronic renal failure is the final result of the development of a variety of kidney diseases. It is a slow and irreversible pathological process caused by damage to the renal parking space, decline in renal function, accumulation of metabolites and toxins, and disturbance of water, electrolyte and acid-base balance. Group of common clinical syndromes. In patients with renal failure, due to the reduction of functional nephrons, the metabolic wastes in the body cannot be fully excreted, and the toxic substances that accumulate in the body leading to pathophysiological changes in the body and cause various symptoms and signs are called uremic toxins. [0003] At first, small molecular solutes suc...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/9066A61P13/12A61P13/00
CPCA61K36/185A61K36/481A61K36/704A61K36/9066A61K2236/331A61K2236/333A61K2236/51A61K2236/53A61K2300/00
Inventor 郭建明段金廒钱大玮郭盛
Owner NANJING UNIVERSITY OF TRADITIONAL CHINESE MEDICINE
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