Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

A kind of sterile oral liquid preparation for children and its preparation method

An oral liquid, children's technology, applied in the field of pharmaceutical preparations, can solve the problems of affecting the curative effect of the drug, unable to effectively remove the pyrogen, destroying the active ingredients of the drug, etc., and achieve the effects of adapting to the characteristics of children, significant curative effect, and small side effects.

Active Publication Date: 2020-07-31
黑龙江童医生儿童生物制药有限公司
View PDF1 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The sterilization link in the production process of oral liquid can only kill germs and cannot effectively remove pyrogens, and the active ingredients of the drug may be destroyed during this process, affecting the efficacy of the drug

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • A kind of sterile oral liquid preparation for children and its preparation method
  • A kind of sterile oral liquid preparation for children and its preparation method

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0028] A sterile oral liquid preparation for children, prepared from the following raw materials in parts by weight: crape myrtle 4, duckweed 3, sternum 3, cassia twig 3, dried ginger 5, asarum 2, schisandra 1, peony 4, half Summer 5, Zhigancao 5, Xylitol 0.7.

Embodiment 2

[0030] A sterile oral liquid preparation for children, prepared from the following raw materials in parts by weight: Lagerstroemia 5, Duckweed 3, Stemone 3, Guizhi 3, Dry ginger 5, Asarum 2, Schisandra 1, Paeonia lactiflora 4, half Summer 4, Roasted Licorice 5, Xylitol 0.35;

[0031] Preparation:

[0032] 1) The oral liquid bottle and bottle cap are cleaned and sterilized in the C-level clean area, and then set aside;

[0033] 2) Take the prescription amount of crape myrtle, duckweed, cassia twig, dried ginger, asarum, schisandra, peony, pinellia, licorice raw materials and mix, add 5 times the total weight of the raw materials in purified water, soak for 0.5 hours, decoct Boil for 100 minutes, filter and separate the decoction and medicine residue;

[0034] 3) Take out the medicine dregs, repeat step 1) twice with the same parameters, combine the decoction, and concentrate the decoction to 0.077 times the total weight of the decoction to obtain a crude product;

[0035] 4) Take the c...

Embodiment 3

[0039] A sterile oral liquid preparation for children, prepared from the following raw materials in parts by weight: Lagerstroemia 3, Duckweed 3, Stemone 1, Guizhi 3, Dried Ginger 3, Asarum 1, Schisandra 1, Peony 3, Half Summer 3, Roasted Licorice 3, Xylitol 1.65;

[0040] Preparation:

[0041] 1) The oral liquid bottle and bottle cap are cleaned and sterilized in the C-level clean area, and then set aside;

[0042] 2) Mix the prescribed amount of crape myrtle, duckweed, cassia twig, dried ginger, asarum, schisandra, schisandra, peony, pinellia, and roasted licorice, add 9 times the total weight of the raw materials in purified water, soak for 1 hour, decoct Boil for 80 minutes, filter and separate the decoction and medicine residue;

[0043] 3) Take out the medicinal residue, repeat step 1) twice with the same parameters, combine the decoction, and concentrate the decoction to 0.4 times the total weight of the decoction to obtain a crude product;

[0044] 4) Take the crude product ob...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention relates to a children sterile oral liquid preparation and a preparation method thereof. The children sterile oral liquid preparation is prepared from a traditional Chinese medicine composition and auxiliary materials according to a weight part ratio of 1: (0.01-0.05), wherein the traditional Chinese medicine composition is mainly prepared from the following raw materials in parts by weight: 3-5 parts of flos lagerstroemiae indicae, 3-5 parts of herba spirodelae, 1-3 parts of radix stemonae, 3-5 parts of cassia twig, 3-5 parts of rhizoma zingiberis, 1-2 parts of herba asari, 1-2 parts of fructus schisandrae, 3-5 parts of herba peony, 3-5 parts of rhizoma pinelliae and 3-5 parts of prepared liquorice root. The children sterile oral liquid preparation provided by the invention is filled in a sterile environment, and is free from any preservative; after being filled, the product does not need to be sterilized, so that the effective components of the product are enabled not to be damaged, and the safety and reliability of the medicine used for children are guaranteed. The children sterile oral liquid preparation is prepared by improving Xiaoqinglong decoction in treatise on febrile diseases, so that the effects of relieving cough and asthma, tonifying qi and regulating the middle warmer as well as dispelling cold and relieving exterior are more greatly improved, and the side effects are reduced; therefore, the children sterile oral liquid preparation can adapt to the conditions that the visceral organs such as liver and kidney of a child are not well developed, and functions of detoxification and excretion are weak.

Description

Technical field [0001] The invention belongs to the field of pharmaceutical preparations, and particularly relates to a sterile oral liquid preparation for children and a preparation method thereof, as well as a traditional Chinese medicine composition for treating children's cough and asthma and a preparation method thereof. Background technique [0002] Coughing is a protective respiratory reflex action for the human body to remove secretions or foreign bodies in the respiratory tract. Although it has its advantages, long-term, frequent, and severe coughing affects work and rest, and even causes sore throat, dumbness, respiratory muscle pain, and even Symptoms such as respiratory tract bleeding. After a child catches a cold, it is easy to cause a cough that does not heal for a long time, and it is easy to cause other children's diseases. Because the internal organs of children are not fully developed, it is advisable to choose a traditional Chinese medicine formula with small s...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/9068A61K9/08A61K47/10A61P11/14A61P11/06
CPCA61K9/0095A61K36/185A61K36/268A61K36/484A61K36/54A61K36/57A61K36/65A61K36/71A61K36/79A61K36/88A61K36/8888A61K36/904A61K36/9068A61K47/10A61K2236/331A61K2236/39A61K2236/51A61K2236/53A61K2300/00
Inventor 徐霜王世岭姜波刘晓磊王娜
Owner 黑龙江童医生儿童生物制药有限公司
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com