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Preparing method and application of medicine composition of gamithromycin

A technology of gamycin and composition, applied in the field of pharmaceutical compositions containing gamycin, can solve the problem of high cost of raw materials, and achieve the effects of long retention time and low cost

Inactive Publication Date: 2017-07-07
LUOYANG HUIZHONG ANIMAL MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] Merial’s trade name is “Zactran Zhong”, which is a gamimycin injection, but the glycerin formal, succinic acid, and thioglycerol used in it have high raw material costs, and gamithromycin is a time-dependent antibiotic. , so how to reduce the cost of Gamithromycin preparations and improve its blood concentration retention time is a technical problem that those skilled in the art need to solve

Method used

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  • Preparing method and application of medicine composition of gamithromycin
  • Preparing method and application of medicine composition of gamithromycin
  • Preparing method and application of medicine composition of gamithromycin

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Embodiment Construction

[0020] The present invention will be further described below in conjunction with specific embodiments, and the advantages and characteristics of the present invention will become clearer along with the description. However, these embodiments are only exemplary and do not constitute any limitation to the scope of the present invention. Those skilled in the art should understand that the details and forms of the technical solutions of the present invention can be modified or replaced without departing from the spirit and scope of the present invention, but these modifications and replacements all fall within the protection scope of the present invention.

[0021] One, the preparation of gamimycin new drug injection

[0022] Embodiment 1-6 is the preparation of gamimycin new composition injection, and table 1 has provided the mass percentage (W / V) percentage composition of each component in the gaminomycin injection in the present invention, according to The content of each comp...

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PUM

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Abstract

The invention provides a composition. The composition is composed of gamithromycin, polyvinylpyrrolidone and a pharmaceutically acceptable carrier. The composition has the advantages of being long in plasma concentration retention time and low in composition cost.

Description

technical field [0001] The invention relates to a pharmaceutical composition containing gamithycin and belongs to the field of veterinary medicine. Background technique [0002] Gamimycin is a new generation of semi-synthetic macrolide antibiotics for livestock and poultry, and it is the main active ingredient of the veterinary antibiotic ZACTRAN developed by Merial, France. The raw material drug is insoluble in water, has a broad antibacterial spectrum, strong antibacterial activity, and low drug resistance. It has inhibitory effects on all Gram-positive bacteria, some Gram-negative bacteria, spirochetes, mycoplasma, and mycoplasma. In 2007, 2010, and 2011, the European Medicines Agency, the Canadian Health Products and Food Administration, and the U.S. Food and Drug Administration approved it for the prevention and treatment of cattle caused by Mannella hemolyticus, Pasteurella multocida, and Histobacter somnus. Respiratory diseases. [0003] The target tissue of gaminom...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/7052A61K47/32A61P31/04
CPCA61K9/0019A61K9/08A61K31/7052A61K47/32
Inventor 张许科刘兴金张晓东
Owner LUOYANG HUIZHONG ANIMAL MEDICINE
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