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A traditional Chinese medicine preparation for treating peptic ulcer, gastritis and reflux esophagitis, its preparation method and application

A technology for reflux esophagitis and peptic ulcer, applied in the field of traditional Chinese medicine, can solve the problems of digestive system flora imbalance, easy recurrence and relapse, unsatisfactory curative effect, etc. The effect of liver and kidney function

Active Publication Date: 2020-09-08
HUBEI UNIV OF TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Although the symptoms can be improved and relieved, it is difficult to cure completely, the curative effect is not satisfactory, and it is easy to relapse and relapse
Need to take western medicine for a long time, which brings many side effects, such as liver and kidney damage, long-term suppression of gastric acid, leading to indigestion, long-term use of antibiotics can also lead to imbalance of digestive system flora, etc.
[0004] Although there are many traditional Chinese medicine preparations on the market to treat stomach problems, one is to treat a certain kind of stomach disease alone, and the other is to cooperate with western medicine as an auxiliary drug for the treatment of ulcer disease, stomach disease, and esophagitis. Traditional Chinese medicine preparation for ulcer and reflux esophagitis
[0005] In conclusion, although Western medicine is partially effective in treating peptic ulcer, reflux esophagitis, and various types of gastritis, it can improve the symptoms, but it cannot completely cure the ulcers.
Traditional Chinese medicines currently on the market are not effective in treating peptic ulcer, gastritis, and reflux esophagitis, and most of them are adjuvant drugs
Therefore, it has brought troubles to the treatment of patients with peptic ulcer, various types of gastritis, and reflux esophagitis, and made such patients with peptic ulcer, various types of gastritis, and chronic esophagitis lose confidence in their treatment.

Method used

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  • A traditional Chinese medicine preparation for treating peptic ulcer, gastritis and reflux esophagitis, its preparation method and application
  • A traditional Chinese medicine preparation for treating peptic ulcer, gastritis and reflux esophagitis, its preparation method and application

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preparation example Construction

[0044] The preparation method of the traditional Chinese medicine preparation in the above embodiment is as follows:

[0045] 1) Wash the raw materials, wash and dry the original Chinese medicinal materials of rhubarb, coptis, panax notoginseng and Bletilla striata for use;

[0046] 2) Weigh each API according to the components shown in each embodiment in Table 1;

[0047] 3) Drying and baking: first wash rhubarb, coptis, panax notoginseng, and Bletilla striata, and bake them in an oven at 50°-60° for 6 hours, take them out and let cool, and then crush the above-mentioned roasted Chinese medicine materials one by one. The medicinal powder was sieved with 80 mesh, and the required amount of each medicine was weighed, mixed and mixed with the quantitative Yunnan Baiyao powder, added with the dosage of auxiliary materials, and prepared into capsules according to the conventional preparation method.

[0048] The above dosage forms can also be granules or tablets or pills.

[0049] The Chin...

Embodiment 8、9、10

[0089] Taking the case of peptic ulcer as the observation object, using its main prescription 1: Rhubarb, Coptis, Panax notoginseng, Bletilla striata and Yunnan Baiyao and formula 2: Rhubarb, Panax notoginseng, Bletilla striata and Yunnan Baiyao; and formula 3: Coptis, Panax notoginseng, Bletilla, Yunnan Baiyao. The above three groups of formulas are used for clinical comparative efficacy evaluation, and the proportions and effects are shown in Table 5 and Table 6 respectively:

[0090] Table 5

[0091]

[0092] Table 6: Comparison of the main formula (Example 8), formula 2 (Example 9), and formula 3 (Example 10)

[0093] Chinese medicine prescription Number of Examples cure Markedly effective effective invalid Main party 1 50 cases 95% 3% 2% 1% Recipe 2 50 cases 72% 10% 12% 6% Recipe 3 50 cases 82% 8% 6% 4%

[0094] The effect evaluation is the same, and the symptoms and gastroscopy results are used as the evaluation criteria.

[0095] The main formula 1 and formula 2 and fo...

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Abstract

The invention provides a traditional Chinese medicine preparation for treating peptic ulcer, gastritis and reflux esophagitis as well as a preparation method and an application thereof. The traditional Chinese medicine preparation provided by the invention is prepared by the steps of: roasting and crushing coptis chinensis, rheum officinale, pseudo-ginseng and bletilla; mixing the optis chinensis, rheum officinale, pseudo-ginseng and bletilla with Yunnan Baiyao in a weight ratio; and adding medicinal auxiliary materials in a medicinal amount. Through scientific proportioning and clinic observation, the formula provided by the invention can effectively and safely treat peptic ulcer, gastritis and esophagitis of all kinds and reflux esophagitis, and is remarkable in curative effect, low in recurrence rate and free of toxic and side effects; the action and curative effect of the preparation can be comparable to those of an anti-ulcer agent, a gastric motor drug, a gastric mucosa protective agent and an anti-helicobacter pylori western medicine. The traditional Chinese medicine preparation provided by the invention has various functions of western medicine in clinical treatment and is the most effective traditional Chinese medicine formula for treating peptic ulcer, gastritis and esophagitis, improving the clinical symptoms and radically treating ulcer and preventing relapse in traditional Chinese medicine treatment at present. A purpose of treating both causes and symptoms is achieved.

Description

Technical field [0001] The invention relates to the field of traditional Chinese medicine, in particular to a traditional Chinese medicine preparation for treating peptic ulcer, gastritis and reflux esophagitis, and a preparation method and application thereof. Background technique [0002] Peptic ulcer, various types of gastritis and reflux esophagitis are common and frequently-occurring diseases. Peptic ulcers include gastric ulcer, bulb ulcer, compound ulcer and so on. Gastritis has chronic gastritis, acute gastritis (acute gastric mucosal disease), and esophagitis has acute and chronic. It can also be divided into reflux esophagitis, gastroesophageal reflux disease, Barrett esophagitis and so on. The main clinical manifestations are: upper abdominal pain, starvation abdominal pain, acid reflux, burning pain behind the breastbone, melena and gastrointestinal bleeding. [0003] At present, Western medicine is mostly used for peptic ulcer, various types of gastritis, and reflux...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/898A61P1/04
CPCA61K36/00A61K36/258A61K36/708A61K36/718A61K36/898A61K2300/00
Inventor 李家新
Owner HUBEI UNIV OF TECH
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