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Traditional Chinese medicinal composition for treating dental ulcer and preparation method of traditional Chinese medicinal composition

A technology for oral ulcers and compositions, which is applied in the field of traditional Chinese medicine compositions for the treatment of oral ulcers and its preparation, which can solve the problems of short action time, unclear curative effect, and great physical damage, and achieve the effect of long-lasting action time and avoiding oral diseases

Inactive Publication Date: 2017-08-11
吉林修正药业新药开发有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Different products and dosage forms have their advantages and disadvantages. Sprays are easy to be swallowed with saliva, and have a short action time in the mouth and a long healing period. Toothpaste containing pharmaceutical ingredients is not a drug, and its curative effect is not clear. The patch effectively solves this problem
At present, most of the patches for the treatment of oral ulcers on the market are chemical drugs. Although they act quickly, they have many side effects and are relatively harmful to the body; some other products rely on anesthesia of the mucosal tissue cells around the ulcer to reduce pain. and play a role

Method used

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  • Traditional Chinese medicinal composition for treating dental ulcer and preparation method of traditional Chinese medicinal composition
  • Traditional Chinese medicinal composition for treating dental ulcer and preparation method of traditional Chinese medicinal composition
  • Traditional Chinese medicinal composition for treating dental ulcer and preparation method of traditional Chinese medicinal composition

Examples

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Effect test

Embodiment 1

[0025] Example 1: Dandelion 100g, Viola chinensis 300g, Lobelia 300g, Radix Radix 300g, crushed into coarse powder, add 8 times the amount of water, decoct and extract twice, each time for 60min, filter, combine the two filtrates, concentrate the filtrate, and dry , crushed; take suitable auxiliary materials (CP934P, HPMC 1:1 mixed as binder; dextrin as filler; micronized silica gel as flow aid) crushed and sieved (100 mesh); the sieved auxiliary materials and extract powder Mixed according to the proportion, added into a die and pressed into tablets, wherein: the content of the extract powder is 75%, the filler accounts for 15%, the binder accounts for 5%, and the glidant accounts for 5%.

Embodiment 2

[0026] Example 2: 200g dandelion, 300g viola, 200g lobelia, 300g isatidis, pulverize into coarse powder, add 8 times the amount of water, decoct and extract twice, each time for 60min, filter, combine the filtrate twice, concentrate the filtrate, and dry , crushed; take suitable auxiliary materials (CP934P, HPMC 1:1 mixed as binder; dextrin as filler; micronized silica gel as flow aid) crushed and sieved (100 mesh); the sieved auxiliary materials and extract powder Mixed according to the proportion, added into a die and pressed into tablets, wherein: the content of the extract powder is 50%, the filler is 25%, the binder is 20%, and the glidant is 5%.

Embodiment 3

[0027] Example 3: 300g dandelion, 200g viola, 300g lobelia, 200g isatidis, crushed into coarse powder, add 8 times the amount of water, decoct and extract twice, each time for 60min, filter, combine the filtrate twice, concentrate the filtrate, and dry , crushed; take suitable auxiliary materials (CP934P, HPMC 1:1 mixed as binder; dextrin as filler; micronized silica gel as flow aid) crushed and sieved (100 mesh); the sieved auxiliary materials and extract powder Mixed according to the proportion, added into a die and pressed into tablets, wherein: the content of the extract powder is 60%, the filler is 15%, the binder is 20%, and the glidant is 5%.

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Abstract

The invention discloses a traditional Chinese medicinal composition for treating dental ulcer and a preparation method of the traditional Chinese medicinal composition. The traditional Chinese medicinal composition consists of water extract powder of 10-30% of herba taraxaci, 10-30% of herba violae, 10-30% of radix isatidis and 10-30% of herba lobeliae chinensis in percentage by weight as well as proper amounts of adjuvants, wherein dosages of the extract powder and the adjuvants are as follows in percentage by weight: 50-75% of the extract powder, 5-25% of a filler, 15-25% of an adhesive and 1-5% of a flow aid. The preparation method comprises the following steps: crushing the herba taraxaci, the herba violae, the herba lobeliae chinensis and the radix isatidis into coarse powder, decocting the coarse powder with water and conducting extracting, so that the water extract powder is prepared; and mixing and tabletting the extract powder and the adjuvants. The traditional Chinese medicinal composition provided by the invention has the advantages that (1) the traditional Chinese medicinal composition can rapidly take effects of relieving swelling and alleviating pain, and the traditional Chinese medicinal composition is long in action duration; (2) the traditional Chinese medicinal composition, which is made from natural medicines, is low in irritation and side effects; and (3) the traditional Chinese medicinal composition not only can be used for treating ulcer surfaces but also can take an effect of protecting surrounding tissues of the ulcer, so that the occurrence of other dental diseases is effectively prevented.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicines, and in particular relates to a traditional Chinese medicine composition for treating oral ulcers and a preparation method thereof. Background technique [0002] Oral ulcer is a common ulcerative injury disease that occurs in the oral mucosa. When it occurs, the pain is severe and the local burning pain is obvious. In severe cases, it will also affect eating and speaking, causing great inconvenience to daily life; it may be accompanied by bad breath and chronic pharyngitis. , Constipation, headache, dizziness, nausea, fatigue, irritability, fever, swollen lymph nodes and other systemic symptoms. [0003] There are many types of products for the treatment of oral ulcers on the market, such as patches, sprays, and toothpaste containing pharmaceutical ingredients. Different products and dosage forms have their advantages and disadvantages. Sprays are easy to be swallowed with s...

Claims

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Application Information

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IPC IPC(8): A61K36/86A61K9/70A61K47/38A61K47/32A61P1/02
CPCA61K9/006A61K9/7046A61K9/7053A61K36/195A61K36/288A61K36/315A61K36/34A61K36/86A61K47/32A61K47/38A61K2236/331A61K2236/39A61K2236/51A61K2300/00
Inventor 徐云赵俞于艳辉许艳茹白冰徐建田淋淋
Owner 吉林修正药业新药开发有限公司
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