A method for determining the content of multi-index components in Xingnaojing injection or its intermediate

A technology for Xingnaojing injection and a determination method, which is applied in the directions of measuring devices, material separation, and analysis of materials, can solve the problems of low detection cost, high detection sensitivity, and inability to accurately determine the content of various index components, and achieve detection cost The effect of low, good sensitivity, good application prospect and use value
CN107091893BActive Publication Date: 2019-06-11ZHEJIANG CHINESE MEDICAL UNIVERSITY
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
ZHEJIANG CHINESE MEDICAL UNIVERSITY
Publication Date
2019-06-11

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Abstract

The invention discloses a measuring method of the contents of multiple index components in a Xingnaojing injection or an intermediate thereof. The method adopts a liquid chromatography analytic technique, and by the aid of a method of quantitative analysis of multi-components by a single marker, the contents of 9 index components in the Xingnaojing injection or the intermediate thereof can be simultaneously measured by using a curdione single reference substance. The method has high detection sensitivity and good accuracy, can evaluate the quality of the Xingnaojing injection or the intermediate thereof at lower cost, can solve the problem that the contents cannot be measured due to lack of the reference substances of the components to be measured, and is helpful to carry out quality control on the Xingnaojing injection more comprehensively.
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Description

technical field

[0001] The invention belongs to the field of content determination of traditional Chinese medicine components, and in particular relates to a method for determining the content of multi-index components in Xingnaojing injection or its intermediate. Background technique

[0002] Xingnaojing Injection is an injection made of four traditional Chinese medicines: musk, turmeric, gardenia, and borneol. Impairment of consciousness, acute alcoholism and other diseases. The current quality standard of Xingnaojing Injection is the National Drug Standard in 2003 (WS 3 -B-3353-98-2003), this standard only identifies the muscone in the injection, carries out the content determination to the borneol, but does not carry out quality control for the composition in gardenia, turmeric.

[0003] A number of documents have reported the content determination methods of muscone and borneol in Xingnaojing injection. There are literature reports on the content determination method...

Claims

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